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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-8-53-63</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3121</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Роль омега ПНЖК в комплексной профилактике и лечении некоторых заболеваний кожи</article-title><trans-title-group xml:lang="en"><trans-title>The role of omega PUFAs in the complex prevention and treatment of certain skin diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3811-9459</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прокопенко</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokopenko</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прокопенко Елена Валерьевна, врач-эндокринолог, диетолог, ведущий менеджер проектов медицинского департамента</p><p>Москва</p></bio><bio xml:lang="en"><p>Prokopenko Elena V., endocrinologist, dietitian, Project Manager of Medical Department</p><p>Moscow</p></bio><email xlink:type="simple">elvprokopenko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4689-3591</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орлова Светлана Владимировна, д. м. н., проф., зав. кафедрой диетологии и клинической нутрициологии, главный научный сотрудник</p><p>Москва</p></bio><bio xml:lang="en"><p>Orlova Svetlana V., DM Sci (habil.), professor, head of Dept of Dietetics and Clinical Nutritiology, Chief Researcher</p><p>Moscow</p></bio><email xlink:type="simple">orlova-sv@rudn.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3220-0333</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитина Елена Александровна, к. м. н., доцент кафедры диетологии и клинической нутрициологии, научный сотрудник</p><p>Москва</p></bio><bio xml:lang="en"><p>Nikitina Elena A., PhD Med, assistant professor of Dept of Dietetics and Clinical Nutritiology, Researcher</p><p>Moscow</p></bio><email xlink:type="simple">nikitina-ea1@rudn.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5203-1082</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Водолазкая</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Vodolazkaya</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Водолазкая Ангелина Николаевна, врач-диетолог</p><p>Москва</p></bio><bio xml:lang="en"><p>Vodolazkaya Angelina N., dietitian</p><p>Moscow</p></bio><email xlink:type="simple">drvodolazkaya@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0548-3414</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балашова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Balashova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Балашова Наталья Валерьевна, к. б. н., ассистент доцент кафедры диетологии и клинической нутрициологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Balashova Natalya V., PhD Bio Sci, assistant of Dept of Dietetics and Clinical Nutritiology</p><p>Moscow</p></bio><email xlink:type="simple">balashovaN77@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4749-731X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пигарева</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pigareva</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пигарева Юлия Анатольевна, к. м. н., зав. отделением клинической диетологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Pigareva Yulia A., PhD Med, head of Dept of Clinical Dietetics</p><p>Moscow</p></bio><email xlink:type="simple">yupigareva@yandex.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ООО «ИНВИТРО»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Health Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов» (РУДН); ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения г. Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia; Scientific and Practical Center for Child Psychoneurology, Moscow Department of Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Австрийская клиника микронутриентной терапии Biogena</institution><country>Россия</country></aff><aff xml:lang="en"><institution>”INVITRO” Limited Liability Company</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов» (РУДН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>ГБУЗ «Городская клиническая больница имени В. В. Виноградова Департамента здравоохранения Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital n. a. V. V. Vinogradov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>14</day><month>06</month><year>2023</year></pub-date><volume>0</volume><issue>8</issue><issue-title>«Диетология и нутрициология» (1)</issue-title><fpage>53</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Прокопенко Е.В., Орлова С.В., Никитина Е.А., Водолазкая А.Н., Балашова Н.В., Пигарева Ю.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Прокопенко Е.В., Орлова С.В., Никитина Е.А., Водолазкая А.Н., Балашова Н.В., Пигарева Ю.А.</copyright-holder><copyright-holder xml:lang="en">Prokopenko E.V., Orlova S.V., Nikitina E.A., Vodolazkaya A.N., Balashova N.V., Pigareva Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3121">https://www.med-alphabet.com/jour/article/view/3121</self-uri><abstract><p>Растущее количество данных о питании показывает, что мы действительно «то, что мы едим», и содержание жирных кислот в нашем рационе имеет далеко идущие физиологические последствия, многие из которых мы только начинаем понимать. Разнообразие жирных кислот присутствует в рационе человека, в кровотоке человека, а также в клетках и тканях человека. Жирные кислоты являются источниками энергии и составляющими мембран. Они обладают биологической активностью, которая влияет на клеточный и тканевой метаболизм, функцию и реакцию, на гормональные и другие сигналы. Благодаря этим эффектам жирные кислоты влияют на здоровье, самочувствие и риски заболеваний. Хотя традиционно наибольший интерес к влиянию жирных кислот на здоровье связан с сердечнососудистыми заболеваниями, метаболическими заболеваниями, такими как диабет 2 типа, воспалительными заболеваниями, нарушениями репродуктивной и нейрокогнитивной функций человека, теперь очевидно, что жирные кислоты влияют и на ряд других заболеваний, в том числе заболеваний кожи, включая атопический дерматит, псориаз, розацеа, акне.</p></abstract><trans-abstract xml:lang="en"><p>A growing body of nutritional evidence shows that we are indeed «what we eat» and the fatty acid content of our diet has far-reaching physiological implications, many of which we are only just beginning to understand. A variety of fatty acids are present in the human diet, in the human bloodstream, and in human cells and tissues. Fatty acids are energy sources and components of membranes. They have biological activities that affect cellular and tissue metabolism, function and response, hormonal and other signals. Through these effects, fatty acids affect health, well-being, and disease risk. While the health effects of fatty acids have traditionally been of greatest interest in cardiovascular disease, metabolic diseases such as diabetes, inflammatory diseases, and reproductive and neurocognitive disorders, it is now clear that fatty acids are also involved in a number of other diseases, including skin diseases, atopic dermatitis, psoriasis, rosacea, acne.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>полиненасыщенные жирные кислоты</kwd><kwd>эйкозапентаеновая кислота</kwd><kwd>докозагексаеновая кислота</kwd><kwd>гамма-линоленовая кислота</kwd><kwd>заболевания кожи</kwd><kwd>атопический дерматит</kwd><kwd>псориаз</kwd><kwd>розацеа</kwd><kwd>акне</kwd></kwd-group><kwd-group xml:lang="en"><kwd>polyunsaturated fatty acids</kwd><kwd>eicosapentaenoic acid</kwd><kwd>docosahexaenoic acid</kwd><kwd>gamma-linolenic acid</kwd><kwd>skin diseases</kwd><kwd>atopic dermatitis</kwd><kwd>psoriasis</kwd><kwd>rosacea</kwd><kwd>acne</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bazinet RP, Layé S. 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