medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2023-8-48-52medalphabet-3120Research ArticleСтатьиПроблема дефицита магния и метаболический синдромThe problem of magnesium deficiency and metabolic syndromehttps://orcid.org/0000-0003-3220-0333НикитинаЕ. А.NikitinaE. A.

Никитина Елена Александровна, к. м. н., ассистент доцент кафедры диетологии и клинической нутрициологии, научный сотрудник

Москва

Nikitina Elena A., PhD Med, assistant professor of Dept of Dietetics and Clinical Nutritiology, Researcher

Moscow

nikitina-ea1@rudn.ruhttps://orcid.org/0000-0002-4689-3591ОрловаС. В.OrlovaS. V.

Орлова Светлана Владимировна, д. м. н., проф., зав. кафедрой диетологии и клинической нутрициологии, главный научный сотрудник

Москва

Orlova Svetlana V., DM Sci (habil.), professor, head of Dept of Dietetics and Clinical Nutritiology, Chief Researcher

Moscow

orlova-sv@rudn.ruhttps://orcid.org/0000-0002-0548-3414БалашоваН. В.BalashovaN. V.

Балашова Наталья Валерьевна, к. б. н., доцент кафедры диетологии и клинической нутрициологии

Москва

Balashova Natalya V., PhD Bio Sci, assistant of Dept of Dietetics and Clinical Nutritiology

Moscow

balashovaN77@mail.ruhttps://orcid.org/0000-0003-4749-731XПигареваЮ. А.PigarevaYu.  A.

Пигарева Юлия Анатольевна, к. м. н., зав. отделением клинической диетологии

Москва

Pigareva Yulia A., PhD Med, head of Dept of Clinical Dietetics

Moscow

yupigareva@yandex.ruФГАОУ ВО «Российский университет дружбы народов» (РУДН); ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения Москвы»РоссияPeoples’ Friendship University of Russia; Scientific and Practical Center for Child Psychoneurology, Moscow Department of HealthRussian FederationФГАОУ ВО «Российский университет дружбы народов» (РУДН)РоссияPeoples’ Friendship University of RussiaRussian FederationГБУЗ «Городская клиническая больница имени В. В. Виноградова Департамента здравоохранения Москвы»РоссияCity Clinical Hospital n. a. V. V. VinogradovRussian Federation20231406202308«Диетология и нутрициология» (1)4852Copyright © Никитина Е.А., Орлова С.В., Балашова Н.В., Пигарева Ю.А., 20232023Никитина Е.А., Орлова С.В., Балашова Н.В., Пигарева Ю.А.Nikitina E.A., Orlova S.V., Balashova N.V., Pigareva Y.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/3120

Наблюдающаяся в настоящее время в развитых странах эпидемия ожирения, инсулинорезистентности и сахарного диабета 2 типа требует поиска новых подходов к профилактике и терапии данных заболеваний. Наряду с несбалансированным по калорийности питанием в развитии метаболических нарушений принимает участие дефицит микронутриентов. Изменение рациона питания современного человека вследствие аграрной и пищевой технологической революций привело к появлению новых микронутриентных дефицитов, в первую очередь магния. Если его гипотоническое действие хорошо изучено, то положительное влияние магния на метаболизм, противовоспалительное и антиоксидантное действие находится в настоящее время в центре пристального внимания исследователей. Применение магния уменьшает инсулинорезистентность, улучшает антропометрические и лабораторные маркеры метаболического синдрома. Выявление дефицита магния, в том числе субклинического, и коррекция магниевого статуса являются важными задачами для профилактики и комплексной терапии метаболического синдрома. Учитывая более высокую биодоступность и меньшую частоту развития побочных эффектов предпочтение целесообразно отдавать органическим солям магния.

The epidemic of obesity, insulin resistance and diabetes mellitus currently observed in developed countries requires new approaches to the prevention and treatment. Besides the hypercaloric diet micronutrient deficiency is involved in the development of metabolic disorders. Recent diet changes due to the agrarian and food technological revolutions has led to the emergence of new micronutrient deficiencies, primarily magnesium. While its hypotonic action is well studied, magnesium’s positive effects on metabolism, anti-inflammatory and antioxidant effects are currently the focus of researchers’ attention. The magnesium preparations reduce insulin resistance, improves anthropometric and laboratory markers of the metabolic syndrome. Detection of magnesium deficiency, including subclinical one, and correction of magnesium status are important tasks for the prevention and complex therapy of the metabolic syndrome. Given the higher bioavailability and lower incidence of side effects, organic magnesium salts are preferable.

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The authors declare that there are no conflicts of interest present.