<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-8-36-47</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3119</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Роль отдельных нейронутриентов в оптимизации алиментарной терапии неврологических пациентов</article-title><trans-title-group xml:lang="en"><trans-title>The role of individual neuronutrients in optimizing nutritional therapy for neurological patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4689-3591</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орлова Светлана Владимировна, д. м. н., проф., зав. кафедрой диетологии и клинической нутрициологии, главный научный сотрудник</p><p>Москва</p></bio><bio xml:lang="en"><p>Orlova Svetlana V., DM Sci (habil.), professor, head of Dept of Dietetics and Clinical Nutritiology, Chief Researcher</p><p>Moscow</p></bio><email xlink:type="simple">orlova-sv@rudn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3220-0333</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитина Елена Александровна, к. м. н., доцент кафедры диетологии и клинической нутрициологии научный сотрудник</p><p>Москва</p></bio><bio xml:lang="en"><p>Nikitina Elena A., PhD Med, assistant professor of Dept of Dietetics and Clinical Nutritiology, Researcher</p><p>Moscow</p></bio><email xlink:type="simple">nikitina-ea1@rudn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0548-3414</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балашова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Balashova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Балашова Наталья Валерьевна, к. б. н., доцент кафедры диетологии и клинической нутрициологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Balashova Natalya V., PhD Bio Sci, assistant professor of Dept of Dietetics and Clinical Nutritiology</p><p>Moscow</p></bio><email xlink:type="simple">balashovaN77@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3738-3792</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грибакин</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Gribakin</surname><given-names>S. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Грибакин Сергей Германович, д. м. н., профессор кафедры диетологии и нутрициологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Gribakin Sergey G., DM Sci (habil.), professor of the Dept of Dietology and Nutrition</p><p>Moscow</p></bio><email xlink:type="simple">serg.gribakin2016@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3811-9459</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прокопенко</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokopenko</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прокопенко Елена Валерьевна, врач-эндокринолог, диетолог, ведущий менеджер проектов медицинского департамента</p><p>Москва</p></bio><bio xml:lang="en"><p>Prokopenko Elena V., endocrinologist, dietitian, Project Manager of Medical Department</p><p>Moscow</p></bio><email xlink:type="simple">elvprokopenko@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5203-1082</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Водолазкая</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Vodolazkaya</surname><given-names>A.  N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Водолазкая Ангелина Николаевна, врач-диетолог</p><p>Москва</p></bio><bio xml:lang="en"><p>Vodolazkaya Angelina N., dietitian</p><p>Moscow</p></bio><email xlink:type="simple">drvodolazkaya@gmail.com</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4749-731X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пигарева</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pigareva</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пигарева Юлия Анатольевна, к. м. н., зав. отделением клинической диетологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Pigareva Yulia A., PhD Med, head of Dept of Clinical Dietetics</p><p>Moscow</p></bio><email xlink:type="simple">yupigareva@yandex.ru</email><xref ref-type="aff" rid="aff-6"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов» (РУДН); ГБУЗ «Научно-практический центр детской психоневрологии Департамента здравоохранения Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia; Scientific and Practical Center for Child Psychoneurology, Moscow Department of Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов» (РУДН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continious Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ООО «ИНВИТРО»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>INVITRO” Limited Liability Company</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Австрийская клиника микронутриентной терапии Biogena</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Austrian clinic for micronutrient therapy Biogena</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ГБУЗ «Городская клиническая больница имени В. В. Виноградова Департамента здравоохранения Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital n. a. V. V. Vinogradov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>14</day><month>06</month><year>2023</year></pub-date><volume>0</volume><issue>8</issue><issue-title>«Диетология и нутрициология» (1)</issue-title><fpage>36</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Орлова С.В., Никитина Е.А., Балашова Н.В., Грибакин С.Г., Прокопенко Е.В., Водолазкая А.Н., Пигарева Ю.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Орлова С.В., Никитина Е.А., Балашова Н.В., Грибакин С.Г., Прокопенко Е.В., Водолазкая А.Н., Пигарева Ю.А.</copyright-holder><copyright-holder xml:lang="en">Orlova S.V., Nikitina E.A., Balashova N.V., Gribakin S.G., Prokopenko E.V., Vodolazkaya A.N., Pigareva Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3119">https://www.med-alphabet.com/jour/article/view/3119</self-uri><abstract><p>Нейродиетология – мультидисциплинарная наука, основанная на знаниях нейронауки и диетологии и имеющая своей целью оптимизацию терапии психоневрологических заболеваний посредством качественного и количественного модулирования составом рационов питания, алиментарную профилактику болезней нервной системы, когда последняя возможна, а также оптимизацию психомоторных и интеллектуальных функций. Следует отметить, что нейродиетология и подходы к выбору лечебного питания с каждым годом занимают все более прочное положение в мировой клинической медицине. Вариабельность нутритивных подходов к практическому лечению неврологической патологии у пациентов отражает многогранность современной нейродиетологии. Поэтому не случайно нейродиетология детского возраста получила в России широкое применение, чего нельзя сказать о нутритивных подходах в лечении взрослых пациентов этого профиля. Кроме того, нарушения нутритивного статуса и отсутствие своевременной его коррекции снижают эффективность реабилитационных мероприятий – важнейшего звена в комплексном лечении неврологических пациентов, профилактике инвалидизации и повышении социальной адаптации. При невозможности обеспечить адекватный уровень потребления пищевых веществ и энергии стандартным путем необходимо своевременно назначить нутритивную поддержку с использованием специализированных пищевых продуктов, включая биологически активные добавки к пище.</p></abstract><trans-abstract xml:lang="en"><p>Neurodietology is a multidisciplinary science based on knowledge of neuroscience and dietology and aiming to optimize the treatment of neuropsychiatric diseases through qualitative and quantitative modulation of the composition of diets, alimentary prevention of diseases of the nervous system, when the latter is possible, as well as optimization of psychomotor and intellectual functions. It should be noted that neurodietology and approaches to the choice of therapeutic nutrition every year occupy an increasingly strong position in world clinical medicine. The variability of nutritional approaches to the practical treatment of neurological pathology in patients reflects the versatility of modern neurodietology. Therefore, it is no coincidence that childhood neurodietology has been widely used in Russia, which cannot be said about nutritional approaches in the treatment of adult patients of this profile. In addition, violations of the nutritional status and the lack of its timely correction reduce the effectiveness of rehabilitation measures – the most important link in the complex treatment of neurological patients, prevention of disability and increasing social adaptation. If it is impossible to provide an adequate level of intake of nutrients and energy in the standard way, it is necessary to prescribe nutritional support in a timely manner using specialized food products, including biologically active food supplements.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>минеральные вещества</kwd><kwd>витамины</kwd><kwd>микроэлементы</kwd><kwd>когнитивные нарушения</kwd><kwd>макро- и микронутриенты</kwd><kwd>нейропротекторы</kwd><kwd>нейронутриенты</kwd><kwd>тирозин</kwd><kwd>холин</kwd><kwd>ГАМК</kwd><kwd>глицин</kwd><kwd>магний</kwd><kwd>пиридоксин</kwd><kwd>пиридоксаль</kwd><kwd>нейродиетология</kwd><kwd>профилактика</kwd><kwd>коррекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>minerals</kwd><kwd>vitamins</kwd><kwd>trace elements</kwd><kwd>cognitive impairment</kwd><kwd>macro-micronutrients</kwd><kwd>neuroprotectors</kwd><kwd>neuronutrients</kwd><kwd>tyrosine</kwd><kwd>choline</kwd><kwd>GABA</kwd><kwd>glycine</kwd><kwd>magnesium</kwd><kwd>pyridoxine</kwd><kwd>pyridoxal</kwd><kwd>neurodietology</kwd><kwd>prevention</kwd><kwd>correction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Magistretti PJ, Allaman I. A cellular perspective on brain energy metabolism and functional imaging. Neuron. 2015 May 20;86(4):883–901. DOI: 10.1016/j.neuron.2015.03.035</mixed-citation><mixed-citation xml:lang="en">Magistretti PJ, Allaman I. A cellular perspective on brain energy metabolism and functional imaging. Neuron. 2015 May 20;86(4):883–901. DOI: 10.1016/j.neuron.2015.03.035</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Kann O, Papageorgiou IE, Draguhn A. Highly energized inhibitory interneurons are a central element for information processing in cortical networks. J. Cereb. Blood Flow Metab. 2014 Aug;34(8):1270–82. Doi: 10.1038/jcbfm.2014.104</mixed-citation><mixed-citation xml:lang="en">Kann O, Papageorgiou IE, Draguhn A. Highly energized inhibitory interneurons are a central element for information processing in cortical networks. J. Cereb. Blood Flow Metab. 2014 Aug;34(8):1270–82. Doi: 10.1038/jcbfm.2014.104</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Studenikin V. M., Gribakin S. G. Shelkovsky V. I., Pak L. A. Neurodietology of childhood. – M., Dynasty, 2012. – 672 p.</mixed-citation><mixed-citation xml:lang="en">Studenikin V. M., Gribakin S. G. Shelkovsky V. I., Pak L. A. Neurodietology of childhood. – M., Dynasty, 2012. – 672 p.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Studenikin V. M. New in pediatric neurodietology. Attending Doctor. 2021; 9(24):6–8. DOI: 10.51793/OS.2021.24.9.001</mixed-citation><mixed-citation xml:lang="en">Studenikin V. M. New in pediatric neurodietology. Attending Doctor. 2021; 9(24):6–8. DOI: 10.51793/OS.2021.24.9.001</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Pyreva E. A., Sorvacheva T. N. Safronova A. N. Nutritional support in the treatment of children with neurological pathology. Issues of children’s dietology. – 2016. – T. 14(1). – From 47–52.</mixed-citation><mixed-citation xml:lang="en">Pyreva E. A., Sorvacheva T. N. Safronova A. N. Nutritional support in the treatment of children with neurological pathology. Issues of children’s dietology. – 2016. – T. 14(1). – From 47–52.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Magistretti P. J. Brain energy metabolism. In Fundamental neuroscience. Ed by. Squire L. R., Berg D., Bloom F. E., du Lac S., Ghosh A., Spitzer N. San Diego: Academic Press, 2008. P. 271–297.</mixed-citation><mixed-citation xml:lang="en">Magistretti P. J. Brain energy metabolism. In Fundamental neuroscience. Ed by. Squire L. R., Berg D., Bloom F. E., du Lac S., Ghosh A., Spitzer N. San Diego: Academic Press, 2008. P. 271–297.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Nogueira-de-Almeida CA, Zotarelli-Filho IJ, Nogueira-de-Almeida ME, Souza CG, Kemp VL, Ramos WS. Neuronutrients And Central Nervous System: A Systematic Review. Cent Nerv Syst Agents Med Chem. 2022 Nov 21. DOI: 10.2174/1871524923666221121123937</mixed-citation><mixed-citation xml:lang="en">Nogueira-de-Almeida CA, Zotarelli-Filho IJ, Nogueira-de-Almeida ME, Souza CG, Kemp VL, Ramos WS. Neuronutrients And Central Nervous System: A Systematic Review. Cent Nerv Syst Agents Med Chem. 2022 Nov 21. DOI: 10.2174/1871524923666221121123937</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Jorgensen E. M. GABA. WormBook. 2005, vol. 31, pp. 1–13.</mixed-citation><mixed-citation xml:lang="en">Jorgensen E. M. GABA. WormBook. 2005, vol. 31, pp. 1–13.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Spiering MJ. The discovery of GABA in the brain. J. Biol. Chem. 2018 Dec 7;293(49):19159–19160. DOI: 10.1074/jbc.CL118.006591</mixed-citation><mixed-citation xml:lang="en">Spiering MJ. The discovery of GABA in the brain. J. Biol. Chem. 2018 Dec 7;293(49):19159–19160. DOI: 10.1074/jbc.CL118.006591</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Roth FC, Draguhn A. GABA metabolism and transport: effects on synaptic efficacy. Neural Plast. 2012;2012:805830. DOI: 10.1155/2012/805830</mixed-citation><mixed-citation xml:lang="en">Roth FC, Draguhn A. GABA metabolism and transport: effects on synaptic efficacy. Neural Plast. 2012;2012:805830. DOI: 10.1155/2012/805830</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hensch TK, Fagiolini M, Mataga N, Stryker MP, Baekkeskov S, Kash SF. Local GABA circuit control of experience-dependent plasticity in developing visual cortex. Science. 1998 Nov 20;282(5393):1504–8. DOI: 10.1126/science.282.5393.1504</mixed-citation><mixed-citation xml:lang="en">Hensch TK, Fagiolini M, Mataga N, Stryker MP, Baekkeskov S, Kash SF. Local GABA circuit control of experience-dependent plasticity in developing visual cortex. Science. 1998 Nov 20;282(5393):1504–8. DOI: 10.1126/science.282.5393.1504</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Behar TN, Schaffner AE, Scott CA, Greene CL, Barker JL. GABA receptor antagonists modulate postmitotic cell migration in slice cultures of embryonic rat cortex. Cereb. Cortex. 2000 Sep;10(9):899–909. DOI: 10.1093/cercor/10.9.899</mixed-citation><mixed-citation xml:lang="en">Behar TN, Schaffner AE, Scott CA, Greene CL, Barker JL. GABA receptor antagonists modulate postmitotic cell migration in slice cultures of embryonic rat cortex. Cereb. Cortex. 2000 Sep;10(9):899–909. DOI: 10.1093/cercor/10.9.899</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Trigo FF, Chat M, Marty A. Enhancement of GABA release through endogenous activation of axonal GABA(A) receptors in juvenile cerebellum. J. Neurosci. 2007 Nov 14;27(46):12452–63. DOI: 10.1523/JNEUROSCI.3413–07.2007</mixed-citation><mixed-citation xml:lang="en">Trigo FF, Chat M, Marty A. Enhancement of GABA release through endogenous activation of axonal GABA(A) receptors in juvenile cerebellum. J. Neurosci. 2007 Nov 14;27(46):12452–63. DOI: 10.1523/JNEUROSCI.3413–07.2007</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Behar TN, Li YX, Tran HT, Ma W, Dunlap V, Scott C, Barker JL. GABA stimulates chemotaxis and chemokinesis of embryonic cortical neurons via calcium-dependent mechanisms. J. Neurosci. 1996 Mar 1;16(5):1808–18. DOI: 10.1523/JNEUROSCI.16–05–01808.1996</mixed-citation><mixed-citation xml:lang="en">Behar TN, Li YX, Tran HT, Ma W, Dunlap V, Scott C, Barker JL. GABA stimulates chemotaxis and chemokinesis of embryonic cortical neurons via calcium-dependent mechanisms. J. Neurosci. 1996 Mar 1;16(5):1808–18. DOI: 10.1523/JNEUROSCI.16–05–01808.1996</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Owens DF, Kriegstein AR. Developmental neurotransmitters? Neuron. 2002 Dec 19;36(6):989–91. DOI: 10.1016/s0896–6273(02)01136–4</mixed-citation><mixed-citation xml:lang="en">Owens DF, Kriegstein AR. Developmental neurotransmitters? Neuron. 2002 Dec 19;36(6):989–91. DOI: 10.1016/s0896–6273(02)01136–4</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Represa A, Ben-Ari Y. Trophic actions of GABA on neuronal development. Trends Neurosci. 2005 Jun;28(6):278–83. DOI: 10.1016/j.tins.2005.03.010</mixed-citation><mixed-citation xml:lang="en">Represa A, Ben-Ari Y. Trophic actions of GABA on neuronal development. Trends Neurosci. 2005 Jun;28(6):278–83. DOI: 10.1016/j.tins.2005.03.010</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Staley KJ, Soldo BL, Proctor WR. Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors. Science. 1995 Aug 18;269(5226):977–81. DOI: 10.1126/science.7638623</mixed-citation><mixed-citation xml:lang="en">Staley KJ, Soldo BL, Proctor WR. Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors. Science. 1995 Aug 18;269(5226):977–81. DOI: 10.1126/science.7638623</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Wang J, Reichling DB, Kyrozis A, MacDermott AB. Developmental loss of GABA- and glycine-induced depolarization and Ca2+ transients in embryonic rat dorsal horn neurons in culture. Eur. J. Neurosci. 1994 Aug 1;6(8):1275–80. DOI: 10.1111/j.1460–9568.1994.tb00317.x</mixed-citation><mixed-citation xml:lang="en">Wang J, Reichling DB, Kyrozis A, MacDermott AB. Developmental loss of GABA- and glycine-induced depolarization and Ca2+ transients in embryonic rat dorsal horn neurons in culture. Eur. J. Neurosci. 1994 Aug 1;6(8):1275–80. DOI: 10.1111/j.1460–9568.1994.tb00317.x</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Obrietan K, van den Pol AN. GABA neurotransmission in the hypothalamus: developmental reversal from Ca2+ elevating to depressing. J. Neurosci. 1995 Jul;15(7 Pt 1):5065–77. DOI: 10.1523/JNEUROSCI.15–07–05065.1995</mixed-citation><mixed-citation xml:lang="en">Obrietan K, van den Pol AN. GABA neurotransmission in the hypothalamus: developmental reversal from Ca2+ elevating to depressing. J. Neurosci. 1995 Jul;15(7 Pt 1):5065–77. DOI: 10.1523/JNEUROSCI.15–07–05065.1995</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">van den Pol AN, Obrietan K, Chen G. Excitatory actions of GABA after neuronal trauma. J Neurosci. 1996 Jul 1;16(13):4283–92. DOI: 10.1523/JNEUROSCI.16–13–04283.1996</mixed-citation><mixed-citation xml:lang="en">van den Pol AN, Obrietan K, Chen G. Excitatory actions of GABA after neuronal trauma. J Neurosci. 1996 Jul 1;16(13):4283–92. DOI: 10.1523/JNEUROSCI.16–13–04283.1996</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Nuss P. Anxiety disorders and GABA neurotransmission: a disturbance of modulation. Neuropsychiatr Dis Treat. 2015 Jan 17;11:165–75. DOI: 10.2147/NDT.S 58841</mixed-citation><mixed-citation xml:lang="en">Nuss P. Anxiety disorders and GABA neurotransmission: a disturbance of modulation. Neuropsychiatr Dis Treat. 2015 Jan 17;11:165–75. DOI: 10.2147/NDT.S 58841</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. DOI: 10.3389/fpsyg.2015.01520</mixed-citation><mixed-citation xml:lang="en">Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. DOI: 10.3389/fpsyg.2015.01520</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Furuya S. An essential role for de novo biosynthesis of L-serine in CNS development. Asia Pac J. Clin. Nutr. 2008;17 Suppl 1:312–5. PMID: 18296366.</mixed-citation><mixed-citation xml:lang="en">Furuya S. An essential role for de novo biosynthesis of L-serine in CNS development. Asia Pac J. Clin. Nutr. 2008;17 Suppl 1:312–5. PMID: 18296366.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Nesterov S. V., Yaguzhinsky L. S., Podoprigora G. I., Nartsissov Y. R. Autocatalytic cycle in the pathogenesis of diabetes mellitus: biochemical and pathophysiological aspects of metabolic therapy with natural amino acids on the example of glycine. Diabetes mellitus. 2018;21(4):283–292.</mixed-citation><mixed-citation xml:lang="en">Nesterov S. V., Yaguzhinsky L. S., Podoprigora G. I., Nartsissov Y. R. Autocatalytic cycle in the pathogenesis of diabetes mellitus: biochemical and pathophysiological aspects of metabolic therapy with natural amino acids on the example of glycine. Diabetes mellitus. 2018;21(4):283–292.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Yalkowsky S. H. Handbook of aqueous solubility data / S. H. Yalkowsky, H. Yan. – CRC Press, 2003. – 581–582 p.</mixed-citation><mixed-citation xml:lang="en">Yalkowsky S. H. Handbook of aqueous solubility data / S. H. Yalkowsky, H. Yan. – CRC Press, 2003. – 581–582 p.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Yakovlev V. N. Normal Physiology: Self-study Modules students: Textbook – 5th ed., Revised. and additional / ed. Yakovlev. – Voronezh: IPF «XXI century», 2012. – 600 p.</mixed-citation><mixed-citation xml:lang="en">Yakovlev V. N. Normal Physiology: Self-study Modules students: Textbook – 5th ed., Revised. and additional / ed. Yakovlev. – Voronezh: IPF «XXI century», 2012. – 600 p.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Minaeva N. N., Litvintseva E. M. Laboratory work in organic chemistry. Khabarovsk: Publishing House of GBOU VPO FESMU, 2013. – 127 p.</mixed-citation><mixed-citation xml:lang="en">Minaeva N. N., Litvintseva E. M. Laboratory work in organic chemistry. Khabarovsk: Publishing House of GBOU VPO FESMU, 2013. – 127 p.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Selivanova O. S., Napalkova S. M. Glycine as a cytoprotective agent in experimental gentamicin nephropathy. News of higher educational institutions. Volga region. Medical Sciences. 2007. – No. 1. – S. 76–82.</mixed-citation><mixed-citation xml:lang="en">Selivanova O. S., Napalkova S. M. Glycine as a cytoprotective agent in experimental gentamicin nephropathy. News of higher educational institutions. Volga region. Medical Sciences. 2007. – No. 1. – S. 76–82.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Cruz M, Maldonado-Bernal C, Mondragón-Gonzalez R, Sanchez-Barrera R, Wacher NH, Carvajal-Sandoval G, Kumate J. Glycine treatment decreases proinflammatory cytokines and increases interferon-gamma in patients with type 2 diabetes. J Endocrinol Invest. 2008 Aug;31(8):694–9. DOI: 10.1007/BF03346417</mixed-citation><mixed-citation xml:lang="en">Cruz M, Maldonado-Bernal C, Mondragón-Gonzalez R, Sanchez-Barrera R, Wacher NH, Carvajal-Sandoval G, Kumate J. Glycine treatment decreases proinflammatory cytokines and increases interferon-gamma in patients with type 2 diabetes. J Endocrinol Invest. 2008 Aug;31(8):694–9. DOI: 10.1007/BF03346417</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Sekhar RV, McKay SV, Patel SG, Guthikonda AP, Reddy VT, Balasubramanyam A, Jahoor F. Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine. Diabetes Care. 2011 Jan;34(1):162–7. DOI: 10.2337/dc10–1006</mixed-citation><mixed-citation xml:lang="en">Sekhar RV, McKay SV, Patel SG, Guthikonda AP, Reddy VT, Balasubramanyam A, Jahoor F. Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine. Diabetes Care. 2011 Jan;34(1):162–7. DOI: 10.2337/dc10–1006</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Baeva E. S. Glycine and its role in the human body // Scientific forum: Medicine, biology and chemistry: Sat. Art. Based on materials of the XXII int. scientific-practical. conf. – No. 4(22). – M., Ed. «MTsNO», 2019. – S. 59–63.</mixed-citation><mixed-citation xml:lang="en">Baeva E. S. Glycine and its role in the human body // Scientific forum: Medicine, biology and chemistry: Sat. Art. Based on materials of the XXII int. scientific-practical. conf. – No. 4(22). – M., Ed. «MTsNO», 2019. – S. 59–63.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Banderet LE, Lieberman HR. Treatment with tyrosine, a neurotransmitter precursor, reduces environmental stress in humans. Brain Res Bull. 1989 Apr;22(4):759–62. DOI: 10.1016/0361–9230(89)90096–8</mixed-citation><mixed-citation xml:lang="en">Banderet LE, Lieberman HR. Treatment with tyrosine, a neurotransmitter precursor, reduces environmental stress in humans. Brain Res Bull. 1989 Apr;22(4):759–62. DOI: 10.1016/0361–9230(89)90096–8</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Клиническая генетика: учебник / Н. П. Бочков, В. П. Пузырев, С. А. Смирнихина; под ред. Н. П. Бочкова. – 4-е изд., доп. и перераб. – М.: ГЭОТАР-Медиа, 2011. – 592 с.</mixed-citation><mixed-citation xml:lang="en">Clinical genetics: textbook / N. P. Bochkov, V. P. Puzyrev, S. A. Smirnikhina; ed. N. P. Bochkov. – 4th ed., add. and reworked. – M.: GEOTAR-Media, 2011. – 592 p.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Holme E, Lindstedt S. Tyrosinaemia type I and NTBC (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione). J. Inherit. Metab. Dis. 1998 Aug;21(5):507–17. DOI: 10.1023/a:1005410820201</mixed-citation><mixed-citation xml:lang="en">Holme E, Lindstedt S. Tyrosinaemia type I and NTBC (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione). J. Inherit. Metab. Dis. 1998 Aug;21(5):507–17. DOI: 10.1023/a:1005410820201</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Semenov A. A. Fundamentals of chemistry of natural compounds: in 2 volumes / A. A. Semenov, V. G. Kartsev. – M.: ICSPF, 2009. – V. 1. – ISBN 978–5–903078–12–7; V. 2. – ISBN 978–5–903078–13–4.</mixed-citation><mixed-citation xml:lang="en">Semenov A. A. Fundamentals of chemistry of natural compounds: in 2 volumes / A. A. Semenov, V. G. Kartsev. – M.: ICSPF, 2009. – V. 1. – ISBN 978–5–903078–12–7; V. 2. – ISBN 978–5–903078–13–4.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Alekseev V. V. Medical laboratory technologies: a guide to clinical laboratory diagnostics: in 2 volumes / V. V. Alekseev and others; ed. A. I. Karpishchenko. – 3rd ed. revised and additional – M.: GEOTAR-Media, 2013. – V. 2. – 792 p. – ISBN 978–5–9704–2275–5 (Vol. 2).</mixed-citation><mixed-citation xml:lang="en">Alekseev V. V. Medical laboratory technologies: a guide to clinical laboratory diagnostics: in 2 volumes / V. V. Alekseev and others; ed. A. I. Karpishchenko. – 3rd ed. revised and additional – M.: GEOTAR-Media, 2013. – V. 2. – 792 p. – ISBN 978–5–9704–2275–5 (Vol. 2).</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Oslopov V. N. Case history of a therapeutic patient / V. N. Oslopov, O. V. Bogoyavlenskaya, Yu. V. Oslopov. – 2nd ed., Rev. and additional – M.: MEDpressinform, 2013. – 152 p. – ISBN 978–5–98322–967–9–27.</mixed-citation><mixed-citation xml:lang="en">Oslopov V. N. Case history of a therapeutic patient / V. N. Oslopov, O. V. Bogoyavlenskaya, Yu. V. Oslopov. – 2nd ed., Rev. and additional – M.: MEDpressinform, 2013. – 152 p. – ISBN 978–5–98322–967–9–27.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Ellaway CJ, Holme E, Standing S, Preece MA, Green A, Ploechl E, Ugarte M, Trefz FK, Leonard JV. Outcome of tyrosinaemia type III. J. Inherit Metab Dis. 2001 Dec;24(8):824–32. DOI: 10.1023/a:1013936107064</mixed-citation><mixed-citation xml:lang="en">Ellaway CJ, Holme E, Standing S, Preece MA, Green A, Ploechl E, Ugarte M, Trefz FK, Leonard JV. Outcome of tyrosinaemia type III. J. Inherit Metab Dis. 2001 Dec;24(8):824–32. DOI: 10.1023/a:1013936107064</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Wiedeman AM, Barr SI, Green TJ, Xu Z, Innis SM, Kitts DD. Dietary Choline Intake: Current State of Knowledge Across the Life Cycle. Nutrients. 2018 Oct 16;10(10):1513. DOI: 10.3390/nu10101513</mixed-citation><mixed-citation xml:lang="en">Wiedeman AM, Barr SI, Green TJ, Xu Z, Innis SM, Kitts DD. Dietary Choline Intake: Current State of Knowledge Across the Life Cycle. Nutrients. 2018 Oct 16;10(10):1513. DOI: 10.3390/nu10101513</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">D’Orlando KJ, Sandage BW Jr. Citicoline (CDP-choline): mechanisms of action and effects in ischemic brain injury. Neurol Res. 1995 Aug;17(4):281–4. DOI: 10.1080/01616412.1995.11740327</mixed-citation><mixed-citation xml:lang="en">D’Orlando KJ, Sandage BW Jr. Citicoline (CDP-choline): mechanisms of action and effects in ischemic brain injury. Neurol Res. 1995 Aug;17(4):281–4. DOI: 10.1080/01616412.1995.11740327</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Zempleni J., Suttie J. W., Gregory J. F. 3rd, Stover P. J. (eds.). Handbook of vitamins. CRC Press, 2013.</mixed-citation><mixed-citation xml:lang="en">Zempleni J., Suttie J. W., Gregory J. F. 3rd, Stover P. J. (eds.). Handbook of vitamins. CRC Press, 2013.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Li Q, Guo-Ross S, Lewis DV, Turner D, White AM, Wilson WA, Swartzwelder HS. Dietary prenatal choline supplementation alters postnatal hippocampal structure and function. J. Neurophysiol. 2004 Apr;91(4):1545–55. DOI: 10.1152/jn.00785.2003</mixed-citation><mixed-citation xml:lang="en">Li Q, Guo-Ross S, Lewis DV, Turner D, White AM, Wilson WA, Swartzwelder HS. Dietary prenatal choline supplementation alters postnatal hippocampal structure and function. J. Neurophysiol. 2004 Apr;91(4):1545–55. DOI: 10.1152/jn.00785.2003</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Zeisel SH. A brief history of choline. Ann Nutr Metab. 2012;61(3):254–8. DOI: 10.1159/000343120</mixed-citation><mixed-citation xml:lang="en">Zeisel SH. A brief history of choline. Ann Nutr Metab. 2012;61(3):254–8. DOI: 10.1159/000343120</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Niculescu MD, Craciunescu CN, Zeisel SH. Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J. 2006 Jan;20(1):43–9. DOI: 10.1096/fj.05–4707com</mixed-citation><mixed-citation xml:lang="en">Niculescu MD, Craciunescu CN, Zeisel SH. Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J. 2006 Jan;20(1):43–9. DOI: 10.1096/fj.05–4707com</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Corbin KD, Zeisel SH. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012 Mar;28(2):159–65. DOI: 10.1097/MOG.0b013e32834e7b4b</mixed-citation><mixed-citation xml:lang="en">Corbin KD, Zeisel SH. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012 Mar;28(2):159–65. DOI: 10.1097/MOG.0b013e32834e7b4b</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Inazu M. Functional Expression of Choline Transporters in the Blood-Brain Barrier. Nutrients. 2019 Sep 20;11(10):2265. DOI: 10.3390/nu11102265</mixed-citation><mixed-citation xml:lang="en">Inazu M. Functional Expression of Choline Transporters in the Blood-Brain Barrier. Nutrients. 2019 Sep 20;11(10):2265. DOI: 10.3390/nu11102265</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Ueland PM. Choline and betaine in health and disease. J. Inherit Metab Dis. 2011 Feb;34(1):3–15. DOI: 10.1007/s10545–010–9088–4</mixed-citation><mixed-citation xml:lang="en">Ueland PM. Choline and betaine in health and disease. J. Inherit Metab Dis. 2011 Feb;34(1):3–15. DOI: 10.1007/s10545–010–9088–4</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Rand JB. Acetylcholine. WormBook. 2007 Jan 30:1–21. DOI: 10.1895/wormbook.1.131.1</mixed-citation><mixed-citation xml:lang="en">Rand JB. Acetylcholine. WormBook. 2007 Jan 30:1–21. DOI: 10.1895/wormbook.1.131.1</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Picciotto MR, Higley MJ, Mineur YS. Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. Neuron. 2012 Oct 4;76(1):116–29. doi: 10.1016/j.neuron.2012.08.036</mixed-citation><mixed-citation xml:lang="en">Picciotto MR, Higley MJ, Mineur YS. Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. Neuron. 2012 Oct 4;76(1):116–29. doi: 10.1016/j.neuron.2012.08.036</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Chen J, Cheuk IWY, Shin VY, Kwong A. Acetylcholine receptors: Key players in cancer development. Surg Oncol. 2019 Dec;31:46–53. doi: 10.1016/j.suronc.2019.09.003.</mixed-citation><mixed-citation xml:lang="en">Chen J, Cheuk IWY, Shin VY, Kwong A. Acetylcholine receptors: Key players in cancer development. Surg Oncol. 2019 Dec;31:46–53. doi: 10.1016/j.suronc.2019.09.003.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Vogt N. Detecting acetylcholine. Nat Methods. 2018 Sep;15(9):648. DOI: 10.1038/s41592–018–0131-y</mixed-citation><mixed-citation xml:lang="en">Vogt N. Detecting acetylcholine. Nat Methods. 2018 Sep;15(9):648. DOI: 10.1038/s41592–018–0131-y</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Gromova OA, Torshin IYu, Gusev EI. Sinergidnye nejroprotektornye effekty tiamina, piridoksina i tsianokobalamina v ramkakh proteoma cheloveka.Farmakokinetika i farmakodinamika. 2017;(1):40–51.</mixed-citation><mixed-citation xml:lang="en">Gromova OA, Torshin IYu, Gusev EI. Sinergidnye nejroprotektornye effekty tiamina, piridoksina i tsianokobalamina v ramkakh proteoma cheloveka.Farmakokinetika i farmakodinamika. 2017;(1):40–51.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Bolaños-Burgos IC, Bernal-Correa AM, Mahecha GAB, Ribeiro ÂM, Kushmerick C. Thiamine Deficiency Increases Intrinsic Excitability of Mouse Cerebellar Purkinje Cells. Cerebellum. 2021 Apr;20(2):186–202. Doi: 10.1007/s12311–020–01202-x</mixed-citation><mixed-citation xml:lang="en">Bolaños-Burgos IC, Bernal-Correa AM, Mahecha GAB, Ribeiro ÂM, Kushmerick C. Thiamine Deficiency Increases Intrinsic Excitability of Mouse Cerebellar Purkinje Cells. Cerebellum. 2021 Apr;20(2):186–202. Doi: 10.1007/s12311–020–01202-x</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Ghatge MS, Al Mughram M, Omar AM, Safo MK. Inborn errors in the vitamin B 6 salvage enzymes associated with neonatal epileptic encephalopathy and other pathologies. Biochimie. 2021 Apr;183:18–29. Doi: 10.1016/j.biochi.2020.12.025</mixed-citation><mixed-citation xml:lang="en">Ghatge MS, Al Mughram M, Omar AM, Safo MK. Inborn errors in the vitamin B 6 salvage enzymes associated with neonatal epileptic encephalopathy and other pathologies. Biochimie. 2021 Apr;183:18–29. Doi: 10.1016/j.biochi.2020.12.025</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Ramos RJ, Pras-Raves ML, Gerrits J, van der Ham M, Willemsen M, Prinsen H, Burgering B, Jans JJ, Verhoeven-Duif NM. Vitamin B 6 is essential for serine de novo biosynthesis. J. Inherit Metab Dis. 2017 Nov;40(6):883–891. DOI: 10.1007/s10545–017–0061–3.</mixed-citation><mixed-citation xml:lang="en">Ramos RJ, Pras-Raves ML, Gerrits J, van der Ham M, Willemsen M, Prinsen H, Burgering B, Jans JJ, Verhoeven-Duif NM. Vitamin B 6 is essential for serine de novo biosynthesis. J. Inherit Metab Dis. 2017 Nov;40(6):883–891. DOI: 10.1007/s10545–017–0061–3.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Claus D, Neundörfer B, Warecka K. The influence of vitamin B 6 deficiency on somatosensory stimulus conduction in the rat. Eur. Arch Psychiatry Neurol Sci. 1984;234(2):102–5. DOI: 10.1007/BF00381215</mixed-citation><mixed-citation xml:lang="en">Claus D, Neundörfer B, Warecka K. The influence of vitamin B 6 deficiency on somatosensory stimulus conduction in the rat. Eur. Arch Psychiatry Neurol Sci. 1984;234(2):102–5. DOI: 10.1007/BF00381215</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Rezazadeh A, Oveisgharan S, Shahidi G, Naghdi R. A Case Report of Homocystinuria With Dystonia and Stroke. Child Neurol. Open. 2014 Aug 26;1(1):2329048X14545870. DOI: 10.1177/2329048X14545870</mixed-citation><mixed-citation xml:lang="en">Rezazadeh A, Oveisgharan S, Shahidi G, Naghdi R. A Case Report of Homocystinuria With Dystonia and Stroke. Child Neurol. Open. 2014 Aug 26;1(1):2329048X14545870. DOI: 10.1177/2329048X14545870</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Nuru M, Muradashvili N, Kalani A, Lominadze D, Tyagi N. High methionine, low folate and low vitamin B 6/B 12 (HM–LF-LV) diet causes neurodegeneration and subsequent short-term memory loss. Metab Brain Dis. 2018 Dec;33(6):1923–1934. DOI: 10.1007/s11011–018–0298-z</mixed-citation><mixed-citation xml:lang="en">Nuru M, Muradashvili N, Kalani A, Lominadze D, Tyagi N. High methionine, low folate and low vitamin B 6/B 12 (HM–LF-LV) diet causes neurodegeneration and subsequent short-term memory loss. Metab Brain Dis. 2018 Dec;33(6):1923–1934. DOI: 10.1007/s11011–018–0298-z</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Kirksey A, Morré DM, Wasynczuk AZ. Neuronal development in vitamin B 6 deficiency. Ann N Y Acad. Sci. 1990;585:202–18. DOI: 10.1111/j.1749–6632.1990.tb28054.x</mixed-citation><mixed-citation xml:lang="en">Kirksey A, Morré DM, Wasynczuk AZ. Neuronal development in vitamin B 6 deficiency. Ann N Y Acad. Sci. 1990;585:202–18. DOI: 10.1111/j.1749–6632.1990.tb28054.x</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Jung HY, Kim W, Hahn KR, Kang MS, Kim TH, Kwon HJ, Nam SM, Chung JY, Choi JH, Yoon YS, Kim DW, Yoo DY, Hwang IK. Pyridoxine Deficiency Exacerbates Neuronal Damage after Ischemia by Increasing Oxidative Stress and Reduces Proliferating Cells and Neuroblasts in the Gerbil Hippocampus. Int J. Mol. Sci. 2020 Aug 4;21(15):5551. DOI: 10.3390/ijms21155551</mixed-citation><mixed-citation xml:lang="en">Jung HY, Kim W, Hahn KR, Kang MS, Kim TH, Kwon HJ, Nam SM, Chung JY, Choi JH, Yoon YS, Kim DW, Yoo DY, Hwang IK. Pyridoxine Deficiency Exacerbates Neuronal Damage after Ischemia by Increasing Oxidative Stress and Reduces Proliferating Cells and Neuroblasts in the Gerbil Hippocampus. Int J. Mol. Sci. 2020 Aug 4;21(15):5551. DOI: 10.3390/ijms21155551</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Akhmedzhanova L. T., Solokha O. A., Strokov I. A. B vitamins in the treatment of neurological diseases. RMJ 2009;17(11):776–83.</mixed-citation><mixed-citation xml:lang="en">Akhmedzhanova L. T., Solokha O. A., Strokov I. A. B vitamins in the treatment of neurological diseases. RMJ 2009;17(11):776–83.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Eckert M, Schejbal P. Therapie von Neuropathien mit einer Vitamin-B-Kombination. Symptomatische Behandlung von schmerzhaften Erkrankungen des peripheren Nervensystems mit einem Kombinationspräparat aus Thiamin, Pyridoxin und Cyanocobalamin [Therapy of neuropathies with a vitamin B combination. Symptomatic treatment of painful diseases of the peripheral nervous system with a combination preparation of thiamine, pyridoxine and cyanocobalamin]. Fortschr Med. 1992 Oct 20;110(29):544–8.</mixed-citation><mixed-citation xml:lang="en">Eckert M, Schejbal P. Therapie von Neuropathien mit einer Vitamin-B-Kombination. Symptomatische Behandlung von schmerzhaften Erkrankungen des peripheren Nervensystems mit einem Kombinationspräparat aus Thiamin, Pyridoxin und Cyanocobalamin [Therapy of neuropathies with a vitamin B combination. Symptomatic treatment of painful diseases of the peripheral nervous system with a combination preparation of thiamine, pyridoxine and cyanocobalamin]. Fortschr Med. 1992 Oct 20;110(29):544–8.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Malouf R, Grimley Evans J. The effect of vitamin B 6 on cognition. Cochrane Database Syst Rev. 2003;(4): CD 004393. doi: 10.1002/14651858.CD004393</mixed-citation><mixed-citation xml:lang="en">Malouf R, Grimley Evans J. The effect of vitamin B 6 on cognition. Cochrane Database Syst Rev. 2003;(4): CD 004393. doi: 10.1002/14651858.CD004393</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Kennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy – A Review. Nutrients. 2016 Jan 27;8(2):68. DOI: 10.3390/nu8020068</mixed-citation><mixed-citation xml:lang="en">Kennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy – A Review. Nutrients. 2016 Jan 27;8(2):68. DOI: 10.3390/nu8020068</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Field DT, Cracknell RO, Eastwood JR, Scarfe P, Williams CM, Zheng Y, Tavassoli T. High-dose Vitamin B 6 supplementation reduces anxiety and strengthens visual surround suppression. Hum Psychopharmacol. 2022 Nov;37(6): e2852. DOI: 10.1002/hup.2852</mixed-citation><mixed-citation xml:lang="en">Field DT, Cracknell RO, Eastwood JR, Scarfe P, Williams CM, Zheng Y, Tavassoli T. High-dose Vitamin B 6 supplementation reduces anxiety and strengthens visual surround suppression. Hum Psychopharmacol. 2022 Nov;37(6): e2852. DOI: 10.1002/hup.2852</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Dakshinamurti S., Dakshinamurti K. Vitamin b6. In: Zempleni J., Suttie J. W., Gregory J. F. III, Stover P. J., editors. Handbook of Vitamins. 5th ed. CRC Press; Boca Raton, FL, USA: 2013.</mixed-citation><mixed-citation xml:lang="en">Dakshinamurti S., Dakshinamurti K. Vitamin b6. In: Zempleni J., Suttie J. W., Gregory J. F. III, Stover P. J., editors. Handbook of Vitamins. 5th ed. CRC Press; Boca Raton, FL, USA: 2013.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Turner RJ, Vink R. Magnesium in the central nervous system New Perspectives in Magnesium Research: Nutrition and Health. 338–355. DOI: 10.1007/978–1–84628–483–0_28</mixed-citation><mixed-citation xml:lang="en">Turner RJ, Vink R. Magnesium in the central nervous system New Perspectives in Magnesium Research: Nutrition and Health. 338–355. DOI: 10.1007/978–1–84628–483–0_28</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Touvier M, Lioret S, Vanrullen I, Boclé JC, Boutron-Ruault MC, Berta JL, Volatier JL. Vitamin and mineral inadequacy in the French population: estimation and application for the optimization of food fortification. Int J Vitam Nutr Res. 2006 Nov;76(6):343–51. DOI: 10.1024/0300–9831.76.6.343</mixed-citation><mixed-citation xml:lang="en">Touvier M, Lioret S, Vanrullen I, Boclé JC, Boutron-Ruault MC, Berta JL, Volatier JL. Vitamin and mineral inadequacy in the French population: estimation and application for the optimization of food fortification. Int J Vitam Nutr Res. 2006 Nov;76(6):343–51. DOI: 10.1024/0300–9831.76.6.343</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Vink R. Magnesium in the CNS: recent advances and developments. Magnes Res. 2016 Mar 1;29(3):95–101. DOI: 10.1684/mrh.2016.0408</mixed-citation><mixed-citation xml:lang="en">Vink R. Magnesium in the CNS: recent advances and developments. Magnes Res. 2016 Mar 1;29(3):95–101. DOI: 10.1684/mrh.2016.0408</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Yary T, Lehto SM, Tolmunen T, Tuomainen TP, Kauhanen J, Voutilainen S, Ruusunen A. Dietary magnesium intake and the incidence of depression: A 20-year follow-up study. J. Affect Disord. 2016 Mar 15;193:94–8. DOI: 10.1016/j.jad.2015.12.056</mixed-citation><mixed-citation xml:lang="en">Yary T, Lehto SM, Tolmunen T, Tuomainen TP, Kauhanen J, Voutilainen S, Ruusunen A. Dietary magnesium intake and the incidence of depression: A 20-year follow-up study. J. Affect Disord. 2016 Mar 15;193:94–8. DOI: 10.1016/j.jad.2015.12.056</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">DiNicolantonio JJ, O’Keefe JH, Wilson W. Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis. Open Heart. 2018 Jan 13;5(1): e000668. doi: 10.1136/openhrt-2017–000668. Erratum in: Open Heart. 2018 Apr 5;5(1): e000668corr1.</mixed-citation><mixed-citation xml:lang="en">DiNicolantonio JJ, O’Keefe JH, Wilson W. Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis. Open Heart. 2018 Jan 13;5(1): e000668. doi: 10.1136/openhrt-2017–000668. Erratum in: Open Heart. 2018 Apr 5;5(1): e000668corr1.</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Vink R, Nechifor M, editors. Magnesium in the Central Nervous System [Internet]. Adelaide (AU): University of Adelaide Press; 2011. PMID: 29919999. www.adelaide.edu.au/press.</mixed-citation><mixed-citation xml:lang="en">Vink R, Nechifor M, editors. Magnesium in the Central Nervous System [Internet]. Adelaide (AU): University of Adelaide Press; 2011. PMID: 29919999. www.adelaide.edu.au/press.</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Guerrera MP, Volpe SL, Mao JJ. Therapeutic uses of magnesium. Am Fam Physician. 2009 Jul 15;80(2):157–62.</mixed-citation><mixed-citation xml:lang="en">Guerrera MP, Volpe SL, Mao JJ. Therapeutic uses of magnesium. Am Fam Physician. 2009 Jul 15;80(2):157–62.</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Slutsky I, Sadeghpour S, Li B, Liu G. Enhancement of synaptic plasticity through chronically reduced Ca2+ flux during uncorrelated activity. Neuron. 2004 Dec 2;44(5):835–49. DOI: 10.1016/j.neuron.2004.11.013</mixed-citation><mixed-citation xml:lang="en">Slutsky I, Sadeghpour S, Li B, Liu G. Enhancement of synaptic plasticity through chronically reduced Ca2+ flux during uncorrelated activity. Neuron. 2004 Dec 2;44(5):835–49. DOI: 10.1016/j.neuron.2004.11.013</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou H, Liu G. Regulation of density of functional presynaptic terminals by local energy supply. Mol Brain. 2015 Jul 17;8:42. DOI: 10.1186/s13041–015–0132-z. Erratum in: Mol Brain. 2015;8:45.</mixed-citation><mixed-citation xml:lang="en">Zhou H, Liu G. Regulation of density of functional presynaptic terminals by local energy supply. Mol Brain. 2015 Jul 17;8:42. DOI: 10.1186/s13041–015–0132-z. Erratum in: Mol Brain. 2015;8:45.</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Léveillé F, El Gaamouch F, Gouix E, Lecocq M, Lobner D, Nicole O, Buisson A. Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors. FASEB J. 2008 Dec;22(12):4258–71. DOI: 10.1096/fj.08–107268</mixed-citation><mixed-citation xml:lang="en">Léveillé F, El Gaamouch F, Gouix E, Lecocq M, Lobner D, Nicole O, Buisson A. Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors. FASEB J. 2008 Dec;22(12):4258–71. DOI: 10.1096/fj.08–107268</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Szydlowska K, Tymianski M. Calcium, ischemia and excitotoxicity. Cell Calcium. 2010 Feb;47(2):122–9. DOI: 10.1016/j.ceca.2010.01.003</mixed-citation><mixed-citation xml:lang="en">Szydlowska K, Tymianski M. Calcium, ischemia and excitotoxicity. Cell Calcium. 2010 Feb;47(2):122–9. DOI: 10.1016/j.ceca.2010.01.003</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Chang JJ, Mack WJ, Saver JL, Sanossian N. Magnesium: potential roles in neurovascular disease. Front Neurol. 2014 Apr 15;5:52. DOI: 10.3389/fneur.2014.00052</mixed-citation><mixed-citation xml:lang="en">Chang JJ, Mack WJ, Saver JL, Sanossian N. Magnesium: potential roles in neurovascular disease. Front Neurol. 2014 Apr 15;5:52. DOI: 10.3389/fneur.2014.00052</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Herroeder S, Schönherr ME, De Hert SG, Hollmann MW. Magnesium – essentials for anesthesiologists. Anesthesiology. 2011 Apr;114(4):971–93. DOI: 10.1097/ALN.0b013e318210483d</mixed-citation><mixed-citation xml:lang="en">Herroeder S, Schönherr ME, De Hert SG, Hollmann MW. Magnesium – essentials for anesthesiologists. Anesthesiology. 2011 Apr;114(4):971–93. DOI: 10.1097/ALN.0b013e318210483d</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Slutsky I, Abumaria N, Wu LJ, Huang C, Zhang L, Li B, Zhao X, Govindarajan A, Zhao MG, Zhuo M, Tonegawa S, Liu G. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010 Jan 28;65(2):165–77. DOI: 10.1016/j.neuron.2009.12.026</mixed-citation><mixed-citation xml:lang="en">Slutsky I, Abumaria N, Wu LJ, Huang C, Zhang L, Li B, Zhao X, Govindarajan A, Zhao MG, Zhuo M, Tonegawa S, Liu G. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010 Jan 28;65(2):165–77. DOI: 10.1016/j.neuron.2009.12.026</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Sun Q, Weinger JG, Mao F, Liu G. Regulation of structural and functional synapse density by L-threonate through modulation of intraneuronal magnesium concentration. Neuropharmacology. 2016 Sep;108:426–39. DOI: 10.1016/j.neuropharm.2016.05.006</mixed-citation><mixed-citation xml:lang="en">Sun Q, Weinger JG, Mao F, Liu G. Regulation of structural and functional synapse density by L-threonate through modulation of intraneuronal magnesium concentration. Neuropharmacology. 2016 Sep;108:426–39. DOI: 10.1016/j.neuropharm.2016.05.006</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Li W, Yu J, Liu Y, Huang X, Abumaria N, Zhu Y, Huang X, Xiong W, Ren C, Liu XG, Chui D, Liu G. Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer’s disease mouse model. Mol. Brain. 2014 Sep 13;7:65. DOI: 10.1186/s13041–014–0065-y</mixed-citation><mixed-citation xml:lang="en">Li W, Yu J, Liu Y, Huang X, Abumaria N, Zhu Y, Huang X, Xiong W, Ren C, Liu XG, Chui D, Liu G. Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer’s disease mouse model. Mol. Brain. 2014 Sep 13;7:65. DOI: 10.1186/s13041–014–0065-y</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Liu G, Weinger JG, Lu ZL, Xue F, Sadeghpour S. Efficacy and Safety of MMFS-01, a Synapse Density Enhancer, for Treating Cognitive Impairment in Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J. Alzheimers Dis. 2016;49(4):971–90. DOI: 10.3233/JAD-150538</mixed-citation><mixed-citation xml:lang="en">Liu G, Weinger JG, Lu ZL, Xue F, Sadeghpour S. Efficacy and Safety of MMFS-01, a Synapse Density Enhancer, for Treating Cognitive Impairment in Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. J. Alzheimers Dis. 2016;49(4):971–90. DOI: 10.3233/JAD-150538</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Tarleton EK, Littenberg B, MacLean CD, Kennedy AG, Daley C. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PLoS One. 2017 Jun 27;12(6): e0180067. DOI: 10.1371/journal.pone.0180067</mixed-citation><mixed-citation xml:lang="en">Tarleton EK, Littenberg B, MacLean CD, Kennedy AG, Daley C. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial. PLoS One. 2017 Jun 27;12(6): e0180067. DOI: 10.1371/journal.pone.0180067</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Tsapanou A, Vlachos GS, Cosentino S, Gu Y, Manly JJ, Brickman AM, Schupf N, Zimmerman ME, Yannakoulia M, Kosmidis MH, Dardiotis E, Hadjigeorgiou G, Sakka P, Stern Y, Scarmeas N, Mayeux R. Sleep and subjective cognitive decline in cognitively healthy elderly: Results from two cohorts. J. Sleep Res. 2019 Oct;28(5): e12759. DOI: 10.1111/jsr.12759</mixed-citation><mixed-citation xml:lang="en">Tsapanou A, Vlachos GS, Cosentino S, Gu Y, Manly JJ, Brickman AM, Schupf N, Zimmerman ME, Yannakoulia M, Kosmidis MH, Dardiotis E, Hadjigeorgiou G, Sakka P, Stern Y, Scarmeas N, Mayeux R. Sleep and subjective cognitive decline in cognitively healthy elderly: Results from two cohorts. J. Sleep Res. 2019 Oct;28(5): e12759. DOI: 10.1111/jsr.12759</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Lin L, Jin C, Fu Z, Zhang B, Bin G, Wu S. Predicting healthy older adult’s brain age based on structural connectivity networks using artificial neural networks. Comput Methods Programs Biomed. 2016 Mar;125:8–17. DOI: 10.1016/j.cmpb.2015.11.012</mixed-citation><mixed-citation xml:lang="en">Lin L, Jin C, Fu Z, Zhang B, Bin G, Wu S. Predicting healthy older adult’s brain age based on structural connectivity networks using artificial neural networks. Comput Methods Programs Biomed. 2016 Mar;125:8–17. DOI: 10.1016/j.cmpb.2015.11.012</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">Sale A, Berardi N, Maffei L. Environment and brain plasticity: towards an endogenous pharmacotherapy. Physiol. Rev. 2014 Jan;94(1):189–234. doi: 10.1152/physrev.00036.2012</mixed-citation><mixed-citation xml:lang="en">Sale A, Berardi N, Maffei L. Environment and brain plasticity: towards an endogenous pharmacotherapy. Physiol. Rev. 2014 Jan;94(1):189–234. doi: 10.1152/physrev.00036.2012</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
