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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2023-1-61-66</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-3010</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Экспериментальное моделирование различных режимов остеотомии при проведении навигационной трепан-биопсии челюстей</article-title><trans-title-group xml:lang="en"><trans-title>Experimental modeling of various osteotomy modes during navigation trepan biopsy of the jaws</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1719-4377</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абраамян</surname><given-names>Л. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Abraamyan</surname><given-names>L. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Левон Казарович Абраамян, аспирант</p><p>кафедры пропедевтики хирургическойстоматологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Levon K. Abraamyan,  Postgraduate student</p><p>propaedeutics of dental surgery</p><p>Moscow</p></bio><email xlink:type="simple">levik6@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4737-8508</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цициашвили</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsitsiashvili</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Михайлович Цициашвили, д. м. н., профессор</p><p>кафедра пропедевтики хирургической стоматологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Alexandr M. Tsitsiashvili, MD, Professor</p><p>Department of propaedeutics of dental surgery</p><p>Moscow</p></bio><email xlink:type="simple">amc777@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5611-3990</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волков</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Вадимович Волков, д. м. н., доцент, старший научный сотрудник, заведующий отделением</p><p>лаборатория соединительной ткани</p><p>кафедра патологической анатомии</p><p>патологоанатомическое отделение</p><p>Москва</p></bio><bio xml:lang="en"><p>Alexei V. Volkov, Doctor of Medical Sciences, Associate Professor, Senior Researcher, Head of the Department</p><p>Priorov CITO</p><p>Department of Pathological Anatomy</p><p>Pathology Department</p><p>Moscow</p></bio><email xlink:type="simple">alex.volkoff@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7163-2553</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лежнев</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lezhnev</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитрий Анатольевич Лежнев, д. м. н., профессор, заведующий кафедрой, профессор кафедры</p><p>кафедра лучевой диагностики</p><p>кафедра терапевтической стоматологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Dmitry A. Lezhnev, Doctor of Medical Sciences, Professor, Head of the Department, Professor of the Department</p><p>Department of Radiation Diagnostics</p><p>Department of Therapeutic Dentistry</p><p>Moscow</p></bio><email xlink:type="simple">lezhnevd@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6073-1591</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панин</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Panin</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андрей Михайлович Панин, д. м. н., профессор, заведующий кафедрой</p><p>кафедра пропедевтики хирургической стоматологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Andrey M. Panin, MD, Professor, Head of the Department</p><p>Department of propaedeutics of dental surgery</p><p>Moscow</p></bio><email xlink:type="simple">profpanin@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «МГМСУ им. А. И. Евдокимова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBEI HE A. I. Yevdokimov MSMSU MOH Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ ТО им. Н. Н. Приорова» Минздрава РФ; ФГАОУ ВО «РУДН»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Priorov CITO; RUDN University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>19</day><month>03</month><year>2023</year></pub-date><volume>1</volume><issue>1</issue><issue-title>Стоматология (1)</issue-title><fpage>61</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Абраамян Л.К., Цициашвили А.М., Волков А.В., Лежнев Д.А., Панин А.М., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Абраамян Л.К., Цициашвили А.М., Волков А.В., Лежнев Д.А., Панин А.М.</copyright-holder><copyright-holder xml:lang="en">Abraamyan L.K., Tsitsiashvili A.M., Volkov A.V., Lezhnev D.A., Panin A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/3010">https://www.med-alphabet.com/jour/article/view/3010</self-uri><abstract><p>   В хирургической стоматологии забор биоматериала челюстей обычно проводят с помощью стоматологических трепанов. В результате остеотомии при трепан-биопсии неизбежно возникает сила трения, которая может приводить к локальной гипертермии и, как следствие, коагуляционному некрозу как костной ткани самой челюсти, так и повреждению получаемого биоптата. Локальный перегрев может приводить к осложненному заживлению костной раны в области проведенной трепан-биопсии, привести к затруднениям при верификации морфологической картины заболевания и, как следствие, дальнейшего лечения пациента. При проведении навигационной трепан-биопсии с применением хирургического шаблона риск гипертермического воздействия увеличивается, и очевидным становится вопрос о выборе скорости вращения. В литературе представлены ограниченные данные о режимах остеотомии с использованием фрезы-трепана при проведении биопсии челюстных костей, в том числе с использованием навигационного хирургического шаблона, что и определило актуальность исследования.   Цель исследования: определение допустимой скорости вращения фрезы-трепана при проведении навигационной трепан-биопсии челюстных костей.   Материалы и методы: материалами исследования стали 20 (по 5) микропрепаратов из трепан-биоптатов бедренной кости крупного рогатого скота, полученных на скоростях 800 об/мин, 500 об/мин, 250 об/мин, 50 об/мин классическим способом; а также 15 (по 5) микропрепаыратов из трепан-биоптатов, полученных на скоростях 350 об/мин, 200 об/мин, 50 об/мин с использованием хирургического навигационного шаблона. Проводилось измерение ширины патологических изменений текториальных свойств остеина вследствие коагуляционного повреждения костного матрикса в мкм в ПО SlideViewer (3DHISTECH) встроенным инструментом для измерения линейных параметров. Статистическую значимость полученных значений определяли с помощью Н-критерия Краскела – Уоллиса.   Результаты: при остеотомии с применением хирургического шаблона на скорости 50 об/мин ширина повреждения костного матрикса достигала до 10 мкм. При увеличении скорости вращения увеличивалась и ширина зоны повреждений: при 200 об/мин – Ме=36,8 мкм, 350 об/мин – Ме=98,6 мкм.   Заключение: при проведении навигационной трепан-биопсии с применением хирургического шаблона рекомендуемая скорость вращения инструмента – до 350 об/мин.</p></abstract><trans-abstract xml:lang="en"><p>   In surgical dentistry, the sampling of the biomaterial of the jaws is usually carried out with the help of dental trepans. As a result of osteotomy, a friction force inevitably arises during trepan biopsy, which can lead to local hyperthermia and, as a consequence, coagulation necrosis of both the bone tissue of the jaw itself and damage to the resulting biopsy. Local overheating can lead to complicated healing of a bone wound in the area of a trepan biopsy, lead to difficulties in verifying the morphological picture of the disease and, as a consequence, further treatment of the patient. When conducting a navigational trepan biopsy using a surgical template, the risk of hyperthermic exposure increases, and the question of choosing the rotation speed becomes obvious. The literature presents limited data on osteotomy regimes using a trepan cutter during jaw bone biopsy, including using a navigational surgical template, which determined the relevance of the study.   The purpose of the study: to determine the permissible speed of rotation of the trepan cutter during the navigation trepan biopsy of the jaw bones.   Materials and methods: 20 (5) micro-preparations were made from trepan biopsies of the femur of cattle, obtained at speeds of 800 rpm, 500 rpm, 250 rpm, 50 rpm in the classical way; 15 (5) micro-preparations were also made from trepan biopsies obtained at speeds of 350 rpm, 200 rpm, 50 rpm using a surgical navigation template. The width of pathological changes in the tectorial properties of ostein due to coagulation damage of the bone matrix in microns was measured using SlideViewer (3DHISTECH), a built-in tool for measuring linear parameters in microns. The statistical significance of the obtained values was determined using the Kraskel – Wallis H-test.   Results: with osteotomy at a speed of 50 rpm, the width of the bone matrix damage reached up to 10 microns. As the rotation speed increased, the width of the damage also increased: at 200 rpm – Me = 36.8 microns, 350 rpm – Me = 98.6 microns.   Conclusion: when conducting a navigational trepan biopsy using a surgical template, the recommended rotation speed of the instrument is up to 350 rpm.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трепан-биопсия</kwd><kwd>коагуляционный некроз</kwd><kwd>режим остеотомии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>trephine biopsy</kwd><kwd>coagulation necrosis</kwd><kwd>osteotomy regimen</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Егоренков В. В. 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