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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2022-31-15-22</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2928</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Возможности и проблемы цифрового мира мультимодальной интервенционной радиологии молочной железы (обзор)</article-title><trans-title-group xml:lang="en"><trans-title>Opportunities and challenges of digital world of multimodal interventional breast radiology (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0920-1549</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рожкова</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Rozhkova</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рожкова Надежда Ивановна, д.м.н., проф., заслуженный деятель науки РФ, зав. Национальным центром онкологии репродуктивных органов МНИОИ им. П.А. Герцена – филиала, проф. кафедры клинической маммологии, лучевой диагностики и лучевой терапии</p><p>Москва</p></bio><bio xml:lang="en"><p>Rozhkova Nadezhda I., PhD Med, professor, Honored Worker of Science of the Russian Federation, head of National Centre for Oncology of Reproductive Organs of Moscow Research Institute n.a. P.A. Herzen – a Branch of, professor at Chair of Clinical Mammology, Radiology and Radiotherapy</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурдина</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Burdina</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бурдина Ирина Игоревна, к.м.н., с.н.с. отделения комплексной диагностики и интервенционной радиологии в маммологии Национального центра онкологии репродуктивных органов МНИОИ им. П.А. Герцена – филиала</p><p>Москва</p></bio><bio xml:lang="en"><p>Burdina Irina I., PhD Med, senior researcher at National Centre for Oncology of Reproductive Organs of Moscow Research Institute n.a. P.A. Herzen – a Branch of</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7154-3326</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Запирова</surname><given-names>С. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Zapirova</surname><given-names>S. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Запирова Самира Бадрузамановна, к.м.н., с.н.с. отделения комплексной  диагностики и интервенционной радиологии в маммологии Национального центра онкологии репродуктивных органов МНИОИ им. П.А. Герцена – филиала</p><p>Москва</p></bio><bio xml:lang="en"><p>Zapirova Samira B., PhD Med, senior researcher at National Centre for Oncology of Reproductive Organs of Moscow Research Institute n.a. P.A. Herzen – a Branch of</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8784-8415</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каприн</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaprin</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каприн Андрей Дмитриевич, д.м.н., проф., акад. РАН, акад. РАО, заслуженный врач РФ, вице-президент Академии онкологии Центральной и Восточной Европы, ген. директор, зав. кафедрой онкологии и рентгенорадиологии им. акад. В.П. Харченко</p><p>Москва</p><p> </p></bio><bio xml:lang="en"><p>Kaprin Andrey D., DM Sci (habil.), professor, academician of RAS, corr. member of the RAE, honored physician of the Russian Federation, CEO, head of Chair of Оncology and Radiology n.a. V.P. Kharchenko</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазо</surname><given-names>М. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazo</surname><given-names>M. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мазо Михаил Львович к.м.н., с.н.с. отделения комплексной диагностики  и интервенционной радиологии в маммологии Национального центра  онкологии репродуктивных органов МНИОИ им. П.А. Герцена – филиала, доцент кафедры клинической маммологии, лучевой диагностики и лучевой терапии</p><p>Москва</p></bio><bio xml:lang="en"><p>Mazo Mikhail L., PhD Med, senior researcher at National Centre for Oncology of Reproductive Organs of Moscow Research Institute n.a. P.A. Herzen – a Branch of, associate professor at Chair of Clinical Mammology Radiology and Radiotherapy</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3495-4895</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Микушин</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikushin</surname><given-names>S. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Микушин Сергей Юрьевич, к.м.н., н.с. отделения комплексной диагностики и интервенционной радиологии в маммологии Национального центра онкологии репродуктивных органов МНИОИ им. П.А. Герцена – филиала, ассистент кафедры клинической маммологии, лучевой диагностики и лучевой терапии</p><p>Москва</p></bio><bio xml:lang="en"><p>Mikushin Sergei Yu., PhD Med, researcher at National Centre for Oncology of Reproductive Organs of Moscow Research Institute n.a. P.A. Herzen – a Branch of, assistant at Chair of Clinical Mammology, Radiology and Radiotherapy</p><p>Moscow</p></bio><email xlink:type="simple">mikushinsergey@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0369-5755</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прокопенко</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokopenko</surname><given-names>S. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прокопенко Сергей Павлович, к.м.н., доцент, зав. отделением комплексной диагностики и интервенционной радиологии в маммологии Национального центра онкологии репродуктивных органов МНИОИ им. П.А. Герцена –филиала, зав. кафедрой клинической маммологии, лучевой диагностики и лучевой терапии</p><p>Москва</p></bio><bio xml:lang="en"><p>Prokopenko Sergei P., PhD Med, associate professor, head of Dept of Complex Diagnostics and Interventional Radiology in Mammology of National Centre for Oncology of Reproductive Organs of Moscow Research Institute n.a. P.A. Herzen – a Branch of, head of Chair of Clinical Mammology, Radiology and Radiotherapy</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9252-7154</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Якобс</surname><given-names>О. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakobs</surname><given-names>O. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Якобс Ольга Эдмундовна, д.м.н., доцент кафедры клинической маммологии, лучевой диагностики и лучевой терапии</p><p>Москва</p></bio><bio xml:lang="en"><p>Yakobs Olga E., PhD Med, associate professor at Chair of Clinical Mammology, Radiology and Radiotherapy</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России; Медицинский институт ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Centre of Radiology; Peoples’ Friendship University of Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Centre of Radiology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России; Медицинский институт ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Centre of Radiology; Peoples’ Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Медицинский институт ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>11</day><month>01</month><year>2023</year></pub-date><volume>0</volume><issue>31</issue><issue-title>Диагностика и онкотерапия (4)</issue-title><fpage>15</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рожкова Н.И., Бурдина И.И., Запирова С.Б., Каприн А.Д., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Рожкова Н.И., Бурдина И.И., Запирова С.Б., Каприн А.Д., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э.</copyright-holder><copyright-holder xml:lang="en">Rozhkova N.I., Burdina I.I., Zapirova S.B., Kaprin A.D., Mazo M.L., Mikushin S.Y., Prokopenko S.P., Yakobs O.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2928">https://www.med-alphabet.com/jour/article/view/2928</self-uri><abstract><sec><title>Введение</title><p>Введение. В статье представлены эволюция внедрения цифровых технологий в систему онкомаммоскрининга, мультимодальные технологии интервенционной радиологии, статистические данные о росте злокачественных новообразований молочной железы в мире и России, показаны преимущества цифровизации лучевой диагностики, междисциплинарной интеграции с технологиями системной биологии «омикс», способствующей развитию нового направления «радиогеномика», а также указано на существующие проблемы внедрения новейших технологий интервенционной радиологии, необходимость подготовки мультимодального специалиста.  </p></sec><sec><title>Цель исследования</title><p>Цель исследования. Показать возможности современных цифровых лучевых неинвазивных и инвазивных технологий, а также необходимость междисциплинарной интеграции иподготовки мультимодальных специалистов для раннего выявления иопределения фенотипа рака молочной железы, повышающего эффективность выбора адекватной лечебной тактики, направленной на увеличение продолжительности и качества жизни пациенток.  </p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Приведены литературные данные о развитии лучевых цифровых методов диагностики заболеваний молочной железы, включающих технологии интервенционной радиологии. Также представлены новые данные онаправлении «радиогеномика», родившегося благодаря междисциплинарной интеграции радиологических цифровых систем, интервенционных технологий и высокотехнологичной системной биологии.  </p></sec><sec><title>Результаты</title><p>Результаты. В обзоре представлено развитие оборудования и лучевых методов раннего распознавания заболеваний молочной железы, основанных на техническом прогрессе, включающем активное внедрение цифровизации и информатизации в медицину. Новые модели искусственного интеллекта выступают в роли помощника врача при скрининге. Показаны преимущества различных вариантов технологий интервенционной радиологии при онкомаммоскрининге для повышения точности патоморфологической диагностики иопределения фенотипа опухолей. Приведены последние данные о целесообразности междисциплинарной интеграции «компьютерного зрения» по признакам медицинской визуализации с возможностями системной биологии в определении фенотипа опухоли с достоверностью корреляции 71%.  </p></sec><sec><title>Заключение</title><p>Заключение. Несомненные преимущества цифровизации и новые возможности интервенционной радиологии в выявлении самых ранних форм заболеваний в междисциплинарном формате открывают перспективу высокоточной диагностики и адекватный выбор органосберегающей лечебной тактики. Подготовка мультимодального специалиста – лучевого диагноста – радиолога-диагноста и интервенционного радиолога, владеющего широким спектром методов лучевой диагностики, включая проведение инвазивных вмешательств, требует коррекции организационных форм работы, новых образовательных программ не только по специальности, но и по основам цифровизации, что обеспечит рациональное и эффективное использование современных достижений науки и техники. </p></sec></abstract><trans-abstract xml:lang="en"><p>The article presents the evolution of the introduction of digital technologies into the oncomammoscreening system, multimodal technologies of interventional radiology, statistics on the growth of malignant breast neoplasms in the world and Russia, shows the advantages of digitalization of radiology, interdisciplinary integration with omix systems biology technologies, which contributes to the development of a new direction of radiogenomics, and also points out the existing problems of introducing the latest technologies of interventional radiology, the need to prepare multimodal specialists.  </p><sec><title>The purpose of the study</title><p>The purpose of the study. To show the possibilities of modern digital radiological non-invasive and invasive technologies, as well as the need for interdisciplinary integration and training of multimodal specialists for the early detection and determination of the phenotype of breast cancer, increasing the effectiveness of choosing adequate treatment tactics aimed at increasing the duration and quality of life of patients.  </p></sec><sec><title>Materials and methods</title><p>Materials and methods. There are given literary data on development of radiological digital methods of diagnostics of breast diseases, including technologies of interventional radiology. New data are also presented on the direction of radiogenomics, born due to the interdisciplinary integration of radiological digital systems, interventional technologies and high-tech systems biology.  </p></sec><sec><title>Results</title><p>Results. The review presents the development of equipment and radiological methods for early recognition of breast diseases, based on technical progress, including the active introduction of digitalization and informatization in medicine. New models of artificial intelligence act as a physician assistant in screening. Advantages of various versions of interventional radiology technologies in oncomammoscreening are shown to increase accuracy of pathomorphological diagnostics and determination of tumor phenotype. The latest data on feasibility of interdisciplinary integration of «computer vision» on signs of medical imaging with capabilities of systems biology in determination of tumor phenotype with correlation validity in 71% are given.  </p></sec><sec><title>Conclusions</title><p>Conclusions. The undeniable advantages of digitalization and the new capabilities of interventional radiology in detecting the earliest forms of diseases in an interdisciplinary format open the prospect of high-precision diagnostics and an adequate choice of organ-saving therapeutic tactics. The training of a multimodal specialist – radiologist – radiologist-diagnostics and interventional radiologist, who has a wide range of methods of radiological diagnostics, including invasive interventions, requires correction of organizational forms of work, new educational programs not only in the specialty, but also in the basics of digitalization, which will ensure the rational and effective use of modern achievements of science and technology. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>цифровые технологии</kwd><kwd>онкомаммоскрининг</kwd><kwd>интервенционная радиология</kwd><kwd>радиогеномика</kwd><kwd>проблемы внедрения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>digital technologies</kwd><kwd>oncomammoscreening</kwd><kwd>interventional radiology</kwd><kwd>radiogenomics</kwd><kwd>problems of implementation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">А.Д. Каприн, Н.И. Рожкова, Нац. руководство. Маммология. Краткое издание. М. ГЭОТАР Медиа. 2021; 376. HELL. Kaprin, N.I. Rozhkova, National management. Mammalogy. Short edition. M. GEOTAR Media. 2021; 376.</mixed-citation><mixed-citation xml:lang="en">А.Д. Каприн, Н.И. Рожкова, Нац. руководство. Маммология. Краткое издание. М. ГЭОТАР Медиа. 2021; 376. HELL. Kaprin, N.I. Rozhkova, National management. Mammalogy. Short edition. M. GEOTAR Media. 2021; 376.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Рассказова Е.А., Рожкова Н.И. Скрининг для ранней диагностики рака молочной железы. Исследования и практика в медицине. 2014; 1 (1): 45–51. https://doi. org/10.17709/2409–2231–2014–1–1–45–51</mixed-citation><mixed-citation xml:lang="en">Рассказова Е.А., Рожкова Н.И. Скрининг для ранней диагностики рака молочной железы. Исследования и практика в медицине. 2014; 1 (1): 45–51. https://doi. org/10.17709/2409–2231–2014–1–1–45–51</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Rasskazova E.A., Rozhkova N.I. Screening for early diagnosis of breast cancer. Research and practice in medicine. 2014; 1 (1): 45–51. https://doi.org/10.17709/2409– 2231–2014–1–1–45–51</mixed-citation><mixed-citation xml:lang="en">Rasskazova E.A., Rozhkova N.I. Screening for early diagnosis of breast cancer. Research and practice in medicine. 2014; 1 (1): 45–51. https://doi.org/10.17709/2409– 2231–2014–1–1–45–51</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Monticciolo D.L. Breast Cancer Screening for Average-Risk Women: Recommendations from the ACR Commission on Breast Imaging. D.L. Monticciolo, M.S. Newell, R.E. Hendrick et al. Journal of the American College of Radiology.2017; Vol. 14 (9). P. 137–1143.</mixed-citation><mixed-citation xml:lang="en">Monticciolo D.L. Breast Cancer Screening for Average-Risk Women: Recommendations from the ACR Commission on Breast Imaging. D.L. Monticciolo, M.S. Newell, R.E. Hendrick et al. Journal of the American College of Radiology.2017; Vol. 14 (9). P. 137–1143.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Wilkinson L, Thomas V et al. Microcalcification on mammography: approaches to interpretation and biopsy. Br J Radiol. 2016 Oct 17. DOI: 10.1259/bjr.20160594.</mixed-citation><mixed-citation xml:lang="en">Wilkinson L, Thomas V et al. Microcalcification on mammography: approaches to interpretation and biopsy. Br J Radiol. 2016 Oct 17. DOI: 10.1259/bjr.20160594.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mammography Quality Standards Act and Program [электронный ресурс]; 2017 https://www.fda.gov/radiationmittingproducts/mammographyqualitystandardsactandprogram/default.htm</mixed-citation><mixed-citation xml:lang="en">Mammography Quality Standards Act and Program [электронный ресурс]; 2017 https://www.fda.gov/radiationmittingproducts/mammographyqualitystandardsactandprogram/default.htm</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Лабазанова П. Г., Прокопенко С.П., Бурдина И. И., Запирова С. Б., Мазо М. Л., Рожкова Н.И., Якобс О.Э. Эффективные неинвазивные и инвазивные технологии лучевой диагностики заболеваний молочной железы (обзор). Новости клинической цитологии. 2020; Т. 24, № 1: 23–27.</mixed-citation><mixed-citation xml:lang="en">Лабазанова П. Г., Прокопенко С.П., Бурдина И. И., Запирова С. Б., Мазо М. Л., Рожкова Н.И., Якобс О.Э. Эффективные неинвазивные и инвазивные технологии лучевой диагностики заболеваний молочной железы (обзор). Новости клинической цитологии. 2020; Т. 24, № 1: 23–27.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Labazanova P.G., Prokopenko S.P., Burdina I.I., Zapirova S.B., Mazo M.L., Rozhkova N.I., Jacobs O.E. Effective non-invasive and invasive technologies for radiodiagnosis of breast diseases (review). News of Clinical Cytology. 2020; V. 24, No. 1: 23–27.</mixed-citation><mixed-citation xml:lang="en">Labazanova P.G., Prokopenko S.P., Burdina I.I., Zapirova S.B., Mazo M.L., Rozhkova N.I., Jacobs O.E. Effective non-invasive and invasive technologies for radiodiagnosis of breast diseases (review). News of Clinical Cytology. 2020; V. 24, No. 1: 23–27.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Siegel R.L., Miller K.D., Jemal A. Cancer statistics 2019. CA A Cancer J Clin. 2019; 69 (1): 7–34. https://doi.org/10.3322/caac.21551 PMID: 306204021</mixed-citation><mixed-citation xml:lang="en">Siegel R.L., Miller K.D., Jemal A. Cancer statistics 2019. CA A Cancer J Clin. 2019; 69 (1): 7–34. https://doi.org/10.3322/caac.21551 PMID: 306204021</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Breast cancer. URL https://www.who.int/cancer/detection/breast-cancer/en (accessed 16.08.2020). Breast cancer. URL https://www.who.int/cancer/detection/ breast-cancer/en (accessed 16.08.2020)</mixed-citation><mixed-citation xml:lang="en">Breast cancer. URL https://www.who.int/cancer/detection/breast-cancer/en (accessed 16.08.2020). Breast cancer. URL https://www.who.int/cancer/detection/ breast-cancer/en (accessed 16.08.2020)</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">DeSantis C.E., Ma J., Gaudet M.M., et al. Breast cancer statis-tics, 2019. CA A Cancer J Clin. 2019; 69: 438–51. https://doi.org/10.3322/caac.21583 PMID: 31577379.</mixed-citation><mixed-citation xml:lang="en">DeSantis C.E., Ma J., Gaudet M.M., et al. Breast cancer statis-tics, 2019. CA A Cancer J Clin. 2019; 69: 438–51. https://doi.org/10.3322/caac.21583 PMID: 31577379.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Кушунина Д.В., Калинина А.М., Дроздова Л.Ю. Выявление рака молочной железы в рамках диспансеризации. Профилактическая медицина. 2019; 22 (4): 37–42. http://dx.doi.org/10.17116/profmed20192204137</mixed-citation><mixed-citation xml:lang="en">Кушунина Д.В., Калинина А.М., Дроздова Л.Ю. Выявление рака молочной железы в рамках диспансеризации. Профилактическая медицина. 2019; 22 (4): 37–42. http://dx.doi.org/10.17116/profmed20192204137</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kushunina D. V., Kalinina A.M., Drozdova L. Yu. Detection of breast cancer in the framework of clinical examination. Preventive medicine. 2019; 22 (4): 37–42. http:// dx.doi.org/10.17116/profmed20192204137</mixed-citation><mixed-citation xml:lang="en">Kushunina D. V., Kalinina A.M., Drozdova L. Yu. Detection of breast cancer in the framework of clinical examination. Preventive medicine. 2019; 22 (4): 37–42. http:// dx.doi.org/10.17116/profmed20192204137</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Всемирная организация здравоохранения: Европейское региональное бюро. Всемирный доклад о раке: исследования рака для развития рака (2020), Отчет о Всеобщем охвате услугами здравоохранения https://www.who.int/healthinfo/ universal_health_coverage/report/uhc_report_2019.pdf</mixed-citation><mixed-citation xml:lang="en">Всемирная организация здравоохранения: Европейское региональное бюро. Всемирный доклад о раке: исследования рака для развития рака (2020), Отчет о Всеобщем охвате услугами здравоохранения https://www.who.int/healthinfo/ universal_health_coverage/report/uhc_report_2019.pdf</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization: Regional Office for Europe. World Cancer Report: Cancer Research for Cancer Development (2020), Universal Health Coverage Report https:// www.who.int/healthinfo/universal_health_coverage/report/uhc_report_2019.pdf</mixed-citation><mixed-citation xml:lang="en">World Health Organization: Regional Office for Europe. World Cancer Report: Cancer Research for Cancer Development (2020), Universal Health Coverage Report https:// www.who.int/healthinfo/universal_health_coverage/report/uhc_report_2019.pdf</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Хрикак ММ, Абдель-Вахаб М, Атун Р и др. (2021) Медицинская визуализация и ядерная медицина: комиссия по онкологии ланцета. Ланцетный Онкол. https://doi. org/10.1016/S1470–2045 (20)30751–8 Hrikak MM, Abdel-Wahab M, Atun R et al. (2021) Medical Imaging and Nuclear Medicine: Lancet Oncology Commission. Lancet Oncol. https://doi.org/10.1016/S1470–2045(20)30751–8</mixed-citation><mixed-citation xml:lang="en">Хрикак ММ, Абдель-Вахаб М, Атун Р и др. (2021) Медицинская визуализация и ядерная медицина: комиссия по онкологии ланцета. Ланцетный Онкол. https://doi. org/10.1016/S1470–2045 (20)30751–8 Hrikak MM, Abdel-Wahab M, Atun R et al. (2021) Medical Imaging and Nuclear Medicine: Lancet Oncology Commission. Lancet Oncol. https://doi.org/10.1016/S1470–2045(20)30751–8</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Оборудование в глобальной радиологической среде: почему мы терпим неудачу, как мы могли бы добиться успеха. https://escholarship.umassmed.edu/cgi/ viewcontent.cgi?article=1079&amp;context=jgr</mixed-citation><mixed-citation xml:lang="en">Оборудование в глобальной радиологической среде: почему мы терпим неудачу, как мы могли бы добиться успеха. https://escholarship.umassmed.edu/cgi/ viewcontent.cgi?article=1079&amp;context=jgr</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Equipment in the Global Radiological Environment: Why We Fail, How We Might Succeed. https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1079&amp;context=jgr</mixed-citation><mixed-citation xml:lang="en">Equipment in the Global Radiological Environment: Why We Fail, How We Might Succeed. https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1079&amp;context=jgr</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Под ред. Рожковой Н.И., Каприна А.Д. 100 страниц о многоликости рака молочной железы. М., ГЭОТАР Медиа. 2020; 128.</mixed-citation><mixed-citation xml:lang="en">Под ред. Рожковой Н.И., Каприна А.Д. 100 страниц о многоликости рака молочной железы. М., ГЭОТАР Медиа. 2020; 128.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Ed. Rozhkova N.I., Kaprin A.D. 100 pages about the many faces of breast cancer. M., GEOTAR Media. 2020; 128.</mixed-citation><mixed-citation xml:lang="en">Ed. Rozhkova N.I., Kaprin A.D. 100 pages about the many faces of breast cancer. M., GEOTAR Media. 2020; 128.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">David C. Howlett, Adrian P. Brady, Nuria Bargalló, Guy Frija, Steve Ebdon-Jackson &amp; Alexandra Karoussou-Schreiner. Текущее состояние выполнения требований Европейского базового стандарта безопасности (2013/59/Евратом): результаты последующего обследования в европейских отделениях радиологии. European Radiology, volume 12, Article number: 139 (2021).</mixed-citation><mixed-citation xml:lang="en">David C. Howlett, Adrian P. Brady, Nuria Bargalló, Guy Frija, Steve Ebdon-Jackson &amp; Alexandra Karoussou-Schreiner. Текущее состояние выполнения требований Европейского базового стандарта безопасности (2013/59/Евратом): результаты последующего обследования в европейских отделениях радиологии. European Radiology, volume 12, Article number: 139 (2021).</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">David C. Howlett, Adrian P. Brady, Nuria Bargalló, Guy Frija, Steve Ebdon-Jackson &amp; Alexandra Karoussou-Schreiner. Current status of implementation of the requirements of the European Basic Safety Standard (2013/59/Euratom): results of a follow-up survey in European radiology departments. European Radiology, volume 12, Article number: 139 (2021).</mixed-citation><mixed-citation xml:lang="en">David C. Howlett, Adrian P. Brady, Nuria Bargalló, Guy Frija, Steve Ebdon-Jackson &amp; Alexandra Karoussou-Schreiner. Current status of implementation of the requirements of the European Basic Safety Standard (2013/59/Euratom): results of a follow-up survey in European radiology departments. European Radiology, volume 12, Article number: 139 (2021).</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">ВОЗ. Рак. Основные факты. URL: http://www.who.int/mediacentre/factsheets/fs297/ru/ WHO. Crayfish. Basic facts. URL: http://www.who.int/mediacentre/factsheets/fs297/ru/</mixed-citation><mixed-citation xml:lang="en">ВОЗ. Рак. Основные факты. URL: http://www.who.int/mediacentre/factsheets/fs297/ru/ WHO. Crayfish. Basic facts. URL: http://www.who.int/mediacentre/factsheets/fs297/ru/</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Социально значимые заболевания населения России в 2015 году (Статистические материалы). М.: ЦНИИОЗ, 2017. 64 с. Socially Significant Diseases of the Russian Population in 2015 (Statistical Materials). M.: TsNIIOZ, 2017. 64 p.</mixed-citation><mixed-citation xml:lang="en">Социально значимые заболевания населения России в 2015 году (Статистические материалы). М.: ЦНИИОЗ, 2017. 64 с. Socially Significant Diseases of the Russian Population in 2015 (Statistical Materials). M.: TsNIIOZ, 2017. 64 p.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Bray F. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. F. Bray, J. Ferlay, I. Soerjomataram et al. CA CANCER J CLIN. 2018. P. 1–31.</mixed-citation><mixed-citation xml:lang="en">Bray F. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. F. Bray, J. Ferlay, I. Soerjomataram et al. CA CANCER J CLIN. 2018. P. 1–31.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Castells X, Domingo L, Corominas JM, Torá-Rocamora I, Quintana MJ, Baré M, et al. Breast cancer risk after diagnosis by screening mammography of nonproliferative or proliferative benign breast disease: A study from a population-based screening program. Breast Cancer Res Treat. 2015; 149 (1): 237–44. DOI: 10.1007/s10549–014–3208-z.</mixed-citation><mixed-citation xml:lang="en">Castells X, Domingo L, Corominas JM, Torá-Rocamora I, Quintana MJ, Baré M, et al. Breast cancer risk after diagnosis by screening mammography of nonproliferative or proliferative benign breast disease: A study from a population-based screening program. Breast Cancer Res Treat. 2015; 149 (1): 237–44. DOI: 10.1007/s10549–014–3208-z.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Iwamoto T. Distinct breast cancer characteristics between screen- and self-detected breast cancers recorded in the Japanese. T. Iwamoto, H. Kumamaru, H. Miyata et al. Breast Cancer Res Treat. 2016. No. 56. P. 485–494.</mixed-citation><mixed-citation xml:lang="en">Iwamoto T. Distinct breast cancer characteristics between screen- and self-detected breast cancers recorded in the Japanese. T. Iwamoto, H. Kumamaru, H. Miyata et al. Breast Cancer Res Treat. 2016. No. 56. P. 485–494.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2018. International Agency for Research on Cancer. World Health Organization. 2018. Режим доступа: https://www.iarc.fr/en/media-centre/ pr/2018/pdfs/pr263_E.pdf</mixed-citation><mixed-citation xml:lang="en">Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2018. International Agency for Research on Cancer. World Health Organization. 2018. Режим доступа: https://www.iarc.fr/en/media-centre/ pr/2018/pdfs/pr263_E.pdf</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Рожкова Н.И., Каприн А.Д, Важенин А.В., Терновой С.К. Очерки истории Российского общества рентгенологов и радиологов, ЧРОО. 2018; 1–295. Rozhkova N.I., Kaprin A.D., Vazhenin A.V., Ternovoy S.K. Essays on the history of the Russian Society of Radiologists and Radiologists. 2018; 1–295.</mixed-citation><mixed-citation xml:lang="en">Рожкова Н.И., Каприн А.Д, Важенин А.В., Терновой С.К. Очерки истории Российского общества рентгенологов и радиологов, ЧРОО. 2018; 1–295. Rozhkova N.I., Kaprin A.D., Vazhenin A.V., Ternovoy S.K. Essays on the history of the Russian Society of Radiologists and Radiologists. 2018; 1–295.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Рожкова Н.И., Бурдина И.И., Запирова С.Б., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э. Оценка диагностической эффективности рентгенологического томосинтеза при заболеваниях молочной железы. REJR. 2020; том 9, № 3: 86–92.</mixed-citation><mixed-citation xml:lang="en">Рожкова Н.И., Бурдина И.И., Запирова С.Б., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э. Оценка диагностической эффективности рентгенологического томосинтеза при заболеваниях молочной железы. REJR. 2020; том 9, № 3: 86–92.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Rozhkova N.I., Burdina I.I., Zapirova S.B., Mazo M.L., Mikushin S. Yu., Prokopenko S.P., Jacobs O.E. Evaluation of the diagnostic efficiency of X-ray tomosynthesis in diseases of the mammary gland. REJR. 2020; vol. 9, No. 3: 86–92.</mixed-citation><mixed-citation xml:lang="en">Rozhkova N.I., Burdina I.I., Zapirova S.B., Mazo M.L., Mikushin S. Yu., Prokopenko S.P., Jacobs O.E. Evaluation of the diagnostic efficiency of X-ray tomosynthesis in diseases of the mammary gland. REJR. 2020; vol. 9, No. 3: 86–92.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Mostafa Alabousi, Nanxi Zha, Jean-Paul Salameh, Lucy Samoilov, Anahita Dehmoobad Sharifabadi, Alex Pozdnyakov, Behnam Sadeghirad, Vivianne Freitas, Matthew D.F. McInnes &amp; Abdullah Alabousi. Digital breast tomosynthesis for breast cancer detection: A diagnostic test accuracy systematic review and meta-analysis. European Radiology. 2020; volume 30, pages 2058–2071.</mixed-citation><mixed-citation xml:lang="en">Mostafa Alabousi, Nanxi Zha, Jean-Paul Salameh, Lucy Samoilov, Anahita Dehmoobad Sharifabadi, Alex Pozdnyakov, Behnam Sadeghirad, Vivianne Freitas, Matthew D.F. McInnes &amp; Abdullah Alabousi. Digital breast tomosynthesis for breast cancer detection: A diagnostic test accuracy systematic review and meta-analysis. European Radiology. 2020; volume 30, pages 2058–2071.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Østeras B.H. Average glandular dose in paired digital mammography and digital breast tomosynthesis acquisitions in a population-based screening program: Effects of measuring breast density, air kerma and beam quality. B.H. Østeras, P. Skaane, R. Gullien et al. Phys Med Biol. 2018. Vol. 63 (3): 035006.</mixed-citation><mixed-citation xml:lang="en">Østeras B.H. Average glandular dose in paired digital mammography and digital breast tomosynthesis acquisitions in a population-based screening program: Effects of measuring breast density, air kerma and beam quality. B.H. Østeras, P. Skaane, R. Gullien et al. Phys Med Biol. 2018. Vol. 63 (3): 035006.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Phi X.A. Digital breast Tomosynthesis for breast cancer screening and diagnosis for breast cancer screening and diagnosis in women with dense breasts – a systematic review and meta-analysis. X.A. Phi, A. Taglifico, N. Houssami et al. BMC Cancer. 2018. Vol.18 (1). P. 380–89.</mixed-citation><mixed-citation xml:lang="en">Phi X.A. Digital breast Tomosynthesis for breast cancer screening and diagnosis for breast cancer screening and diagnosis in women with dense breasts – a systematic review and meta-analysis. X.A. Phi, A. Taglifico, N. Houssami et al. BMC Cancer. 2018. Vol.18 (1). P. 380–89.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Pisano E.D. Is Tomosynthesis the Future of Breast Cancer Screening? E.D. Pisano. Radiology 2018. Vol. 287. P. 47–48.</mixed-citation><mixed-citation xml:lang="en">Pisano E.D. Is Tomosynthesis the Future of Breast Cancer Screening? E.D. Pisano. Radiology 2018. Vol. 287. P. 47–48.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Мазо М. Л., Рожкова Н. И., Бурдина И. И., Запирова С. Б., Прокопенко С. П., Якобс О.Э. Инвазивная лучевая диагностика рака молочной железы. Тонкоигольная биопсия или трепанбиопсия? Мед. визуализация. 2015; № 4.</mixed-citation><mixed-citation xml:lang="en">Мазо М. Л., Рожкова Н. И., Бурдина И. И., Запирова С. Б., Прокопенко С. П., Якобс О.Э. Инвазивная лучевая диагностика рака молочной железы. Тонкоигольная биопсия или трепанбиопсия? Мед. визуализация. 2015; № 4.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Mazo M.L., Rozhkova N.I., Burdina I.I., Zapirova S.B., Prokopenko S.P., Jacobs O.E. Invasive radiodiagnosis of breast cancer. Fine needle biopsy or trepanbiopsy? Med. visualization. 2015; No. 4.</mixed-citation><mixed-citation xml:lang="en">Mazo M.L., Rozhkova N.I., Burdina I.I., Zapirova S.B., Prokopenko S.P., Jacobs O.E. Invasive radiodiagnosis of breast cancer. Fine needle biopsy or trepanbiopsy? Med. visualization. 2015; No. 4.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Лабазанова П. Г., Буданова М.В., Бурдина И.И., Запирова С.Б., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Рожкова Н.И. Маммографическая плотность – маркер повышенного риска развития рака молочной железы. Медицинский алфавит. Диагностика и онкотерапия. 2021; № 19: 41–48.</mixed-citation><mixed-citation xml:lang="en">Лабазанова П. Г., Буданова М.В., Бурдина И.И., Запирова С.Б., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Рожкова Н.И. Маммографическая плотность – маркер повышенного риска развития рака молочной железы. Медицинский алфавит. Диагностика и онкотерапия. 2021; № 19: 41–48.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Labazanova P.G., Budanova M.V., Burdina I.I., Zapirova S.B., Mazo M. L., Mikushin S. Yu., Prokopenko S.P., Rozhkova N.I. Mammographic density is a marker of an increased risk of developing breast cancer. Medical alphabet. Diagnostics and Oncotherapy. 2021; No. 19: 41–48.</mixed-citation><mixed-citation xml:lang="en">Labazanova P.G., Budanova M.V., Burdina I.I., Zapirova S.B., Mazo M. L., Mikushin S. Yu., Prokopenko S.P., Rozhkova N.I. Mammographic density is a marker of an increased risk of developing breast cancer. Medical alphabet. Diagnostics and Oncotherapy. 2021; No. 19: 41–48.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Гажонова В.Е. Ультразвуковое исследование молочных желез. М. ГЭОТАР Медиа, 2020, 523. Gazhonova V.E. Ultrasound examination of the mammary glands. M. GEOTAR Media, 2020, 523.</mixed-citation><mixed-citation xml:lang="en">Гажонова В.Е. Ультразвуковое исследование молочных желез. М. ГЭОТАР Медиа, 2020, 523. Gazhonova V.E. Ultrasound examination of the mammary glands. M. GEOTAR Media, 2020, 523.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А.Д., Рожкова Н.И. Соавторы: Бурдина И.И., С.Б. Запирова, Мазо М.Л., Прокопенко С.П., Семикопенко В.А., Якобс О.Э. Профилактика – приоритет клинической маммологии, М. СИМК, 2015, 196.</mixed-citation><mixed-citation xml:lang="en">Каприн А.Д., Рожкова Н.И. Соавторы: Бурдина И.И., С.Б. Запирова, Мазо М.Л., Прокопенко С.П., Семикопенко В.А., Якобс О.Э. Профилактика – приоритет клинической маммологии, М. СИМК, 2015, 196.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Kaprin A.D., Rozhkova N.I. Co-authors: Burdina I.I., S.B. Zapirova, Mazo M.L., Prokopenko S.P., Semikopenko V.A., Yakobs O.E. Prevention is a priority of clinical mammology, M. SIMK, 2015, 196.</mixed-citation><mixed-citation xml:lang="en">Kaprin A.D., Rozhkova N.I. Co-authors: Burdina I.I., S.B. Zapirova, Mazo M.L., Prokopenko S.P., Semikopenko V.A., Yakobs O.E. Prevention is a priority of clinical mammology, M. SIMK, 2015, 196.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Рожкова Н.И., Каприн А.Д. Национальное руководство по маммологии, 2-е изд. ГЭОТАР-Медиа, М. 2016. 496.</mixed-citation><mixed-citation xml:lang="en">Рожкова Н.И., Каприн А.Д. Национальное руководство по маммологии, 2-е изд. ГЭОТАР-Медиа, М. 2016. 496.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Rozhkova N.I., Kaprin A.D. National Guide to Mammology, 2nd ed. GEOTAR-Media, M. 2016. 496.</mixed-citation><mixed-citation xml:lang="en">Rozhkova N.I., Kaprin A.D. National Guide to Mammology, 2nd ed. GEOTAR-Media, M. 2016. 496.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Рожкова Н.И., Мазо М.Л., Якобс О.Э., Микушин С.Ю. Опыт использования виртуальной сонографии молочной железы. Вестник Ри Р. 2014; № 1: 23–32.</mixed-citation><mixed-citation xml:lang="en">Рожкова Н.И., Мазо М.Л., Якобс О.Э., Микушин С.Ю. Опыт использования виртуальной сонографии молочной железы. Вестник Ри Р. 2014; № 1: 23–32.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Rozhkova N.I., Mazo M.L., Jacobs O.E., Mikushin S. Yu. Experience in the use of virtual breast sonography. Bulletin of R&amp;R. 2014; No. 1: 23–32.</mixed-citation><mixed-citation xml:lang="en">Rozhkova N.I., Mazo M.L., Jacobs O.E., Mikushin S. Yu. Experience in the use of virtual breast sonography. Bulletin of R&amp;R. 2014; No. 1: 23–32.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Мазо М. Л., Рожкова Н. И., Бурдина И. И., Запирова С. Б., Прокопенко С. П., Якобс О.Э. Инвазивная лучевая диагностика рака молочной железы. Тонкоигольная биопсия или трепанбиопсия? Мед. визуализация. 2015; № 4.</mixed-citation><mixed-citation xml:lang="en">Мазо М. Л., Рожкова Н. И., Бурдина И. И., Запирова С. Б., Прокопенко С. П., Якобс О.Э. Инвазивная лучевая диагностика рака молочной железы. Тонкоигольная биопсия или трепанбиопсия? Мед. визуализация. 2015; № 4.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Mazo M.L., Rozhkova N.I., Burdina I.I., Zapirova S.B., Prokopenko S.P., Jacobs O.E. Invasive radiodiagnosis of breast cancer. Fine needle biopsy or trepanbiopsy? Med. Visualization. 2015; No. 4.</mixed-citation><mixed-citation xml:lang="en">Mazo M.L., Rozhkova N.I., Burdina I.I., Zapirova S.B., Prokopenko S.P., Jacobs O.E. Invasive radiodiagnosis of breast cancer. Fine needle biopsy or trepanbiopsy? Med. Visualization. 2015; No. 4.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Якобс О.Э., Рожкова Н.И., Каприн А.Д. Возможности соноэластографии в дифференцируальной диагностике заболеваний молочной железы, сопровождающихся скоплением микрокальцинатов. Акушерство и гинекология: Новости. Мнения. Обучение. 2017; 1 (15): 69–75.</mixed-citation><mixed-citation xml:lang="en">Якобс О.Э., Рожкова Н.И., Каприн А.Д. Возможности соноэластографии в дифференцируальной диагностике заболеваний молочной железы, сопровождающихся скоплением микрокальцинатов. Акушерство и гинекология: Новости. Мнения. Обучение. 2017; 1 (15): 69–75.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Jacobs O.E., Rozhkova N.I., Kaprin A.D. Possibilities of sonoelastography in differential diagnosis of breast diseases accompanied by accumulation of microcalcifications. Obstetrics and Gynecology: News. Opinions. Education. 2017; 1 (15): 69–75.</mixed-citation><mixed-citation xml:lang="en">Jacobs O.E., Rozhkova N.I., Kaprin A.D. Possibilities of sonoelastography in differential diagnosis of breast diseases accompanied by accumulation of microcalcifications. Obstetrics and Gynecology: News. Opinions. Education. 2017; 1 (15): 69–75.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Fallenberg E.M., Dromain C., Diekmann F. et al. Contrast-enhanced spectral mammography versus MRI: Initial results in the detection of breast cancer and assessment of tumor size. European Radiology. 2014; 24 (1): 256–264.</mixed-citation><mixed-citation xml:lang="en">Fallenberg E.M., Dromain C., Diekmann F. et al. Contrast-enhanced spectral mammography versus MRI: Initial results in the detection of breast cancer and assessment of tumor size. European Radiology. 2014; 24 (1): 256–264.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Рожкова Н.И., Горшков В.А., Мазо М.Л. с соавт. Цифровая маммологическая клиника. Технологии визуализации. Под ред. Н.И. Рожковой, В.А. Горшкова. М.: СИМК, 2012; 151 c.</mixed-citation><mixed-citation xml:lang="en">Рожкова Н.И., Горшков В.А., Мазо М.Л. с соавт. Цифровая маммологическая клиника. Технологии визуализации. Под ред. Н.И. Рожковой, В.А. Горшкова. М.: СИМК, 2012; 151 c.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Rozhkova N.I., Gorshkov V.A., Mazo M.L. et al. Digital mammology clinic. Technologies of visualization. Ed. N.I. Rozhkova, V.A. Gorshkov. M.: SIMK. 2012; 151 p.</mixed-citation><mixed-citation xml:lang="en">Rozhkova N.I., Gorshkov V.A., Mazo M.L. et al. Digital mammology clinic. Technologies of visualization. Ed. N.I. Rozhkova, V.A. Gorshkov. M.: SIMK. 2012; 151 p.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">CESM Academy 2014 (Contrast Enhanced Spectral Mammography), 13–14 November-Rome, Conference: GE Imaging at work. Sheraton Parco Le Medici Hotel Via Salvatore Rebecchini, Rome, Italy, 13–14 November, 2014.</mixed-citation><mixed-citation xml:lang="en">CESM Academy 2014 (Contrast Enhanced Spectral Mammography), 13–14 November-Rome, Conference: GE Imaging at work. Sheraton Parco Le Medici Hotel Via Salvatore Rebecchini, Rome, Italy, 13–14 November, 2014.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Provenzano E., Ulaner G.A., Chin S.-F. Pet Clinics. 2018. T. 13, No. 3: 325–338.</mixed-citation><mixed-citation xml:lang="en">Provenzano E., Ulaner G.A., Chin S.-F. Pet Clinics. 2018. T. 13, No. 3: 325–338.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2018. International Agency for Research on Cancer. World Health Organization. 2018. Режим доступа: https://www.iarc.fr/en/media-centre/ pr/2018/pdfs/pr263_E.pdf</mixed-citation><mixed-citation xml:lang="en">Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2018. International Agency for Research on Cancer. World Health Organization. 2018. Режим доступа: https://www.iarc.fr/en/media-centre/ pr/2018/pdfs/pr263_E.pdf</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Mammography Quality Standards Act and Program [электронный ресурс] 2017. Режим доступа: https://www.fda.gov/radiation-emittingproducts/mammography-qualitystandardsactandprogram/default.htm</mixed-citation><mixed-citation xml:lang="en">Mammography Quality Standards Act and Program [электронный ресурс] 2017. Режим доступа: https://www.fda.gov/radiation-emittingproducts/mammography-qualitystandardsactandprogram/default.htm</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Monticciolo D.L. Breast Cancer Screening for Average-Risk Women: Recommendations From the ACR Commission on Breast Imaging. D.L. Monticciolo, M.S. Newell, R.E. Hendrick et al. Journal of the American College of Radiology. 2017. Vol. 14 (9). P. 1137–1143.</mixed-citation><mixed-citation xml:lang="en">Monticciolo D.L. Breast Cancer Screening for Average-Risk Women: Recommendations From the ACR Commission on Breast Imaging. D.L. Monticciolo, M.S. Newell, R.E. Hendrick et al. Journal of the American College of Radiology. 2017. Vol. 14 (9). P. 1137–1143.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Iwamoto T. Distinct breast cancer characteristics between screen- and self-detected breast cancers recorded in the Japanese. T. Iwamoto, H. Kumamaru, H. Miyata et al. Breast Cancer Res Treat. 2016. No. 56. P. 485–494.</mixed-citation><mixed-citation xml:lang="en">Iwamoto T. Distinct breast cancer characteristics between screen- and self-detected breast cancers recorded in the Japanese. T. Iwamoto, H. Kumamaru, H. Miyata et al. Breast Cancer Res Treat. 2016. No. 56. P. 485–494.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Atasoy M.M., Tasali N., Cubuk R., Narin B., Deveci U., Yener N., &amp; Celik L. (2015). Vacuum-assisted stereotactic biopsy for isolated BI-RADS4 microcalcifications: Evaluation with histopathology and midterm follow-up results. Diagn Interv Radiol., 21 (1), 22–27. DOI: 10.5152/dir.2014.14139.</mixed-citation><mixed-citation xml:lang="en">Atasoy M.M., Tasali N., Cubuk R., Narin B., Deveci U., Yener N., &amp; Celik L. (2015). Vacuum-assisted stereotactic biopsy for isolated BI-RADS4 microcalcifications: Evaluation with histopathology and midterm follow-up results. Diagn Interv Radiol., 21 (1), 22–27. DOI: 10.5152/dir.2014.14139.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Choi E.R., Han B.K., Ko E.S., Ko E.Y., Choi J.S., Cho E.Y., &amp; Nam S.J. (2015). Initial experience with a wireless ultrasound-guided vacuum-assisted breast biopsy device. PLoS ONE, 10 (12), no pagination.</mixed-citation><mixed-citation xml:lang="en">Choi E.R., Han B.K., Ko E.S., Ko E.Y., Choi J.S., Cho E.Y., &amp; Nam S.J. (2015). Initial experience with a wireless ultrasound-guided vacuum-assisted breast biopsy device. PLoS ONE, 10 (12), no pagination.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Keranen A.K., Haapea M., &amp; Rissanen T. (2015). Ultrasonography as a Guiding Method in Breast Micro-Calcification Vacuum-Assisted Biopsies. Ultraschall Med, 22, 22.</mixed-citation><mixed-citation xml:lang="en">Keranen A.K., Haapea M., &amp; Rissanen T. (2015). Ultrasonography as a Guiding Method in Breast Micro-Calcification Vacuum-Assisted Biopsies. Ultraschall Med, 22, 22.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">McDonald E.S. Effectiveness of Digital Breast Tomosynthesis Compared with Digital Mammography: Outcomes Analysis From 3 Years of Breast Cancer Screening. E.S. McDonald, A. Oustimov, S.P. Weinstein et al. JAMA Oncol. 2016. Vol. 2 (6). P. 737–43.</mixed-citation><mixed-citation xml:lang="en">McDonald E.S. Effectiveness of Digital Breast Tomosynthesis Compared with Digital Mammography: Outcomes Analysis From 3 Years of Breast Cancer Screening. E.S. McDonald, A. Oustimov, S.P. Weinstein et al. JAMA Oncol. 2016. Vol. 2 (6). P. 737–43.</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Лучевая диагностика в маммологии. Н.И. Рожкова, И.И. Бурдина, А.Р. Дабагов и др. М.: СИМК, 2014. 112 с.</mixed-citation><mixed-citation xml:lang="en">Лучевая диагностика в маммологии. Н.И. Рожкова, И.И. Бурдина, А.Р. Дабагов и др. М.: СИМК, 2014. 112 с.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Radiation diagnostics in mammology. N.I. Rozhkova, I.I. Burdina, A.R. Dabagov et al. M.: SIMK, 2014. 112 p.</mixed-citation><mixed-citation xml:lang="en">Radiation diagnostics in mammology. N.I. Rozhkova, I.I. Burdina, A.R. Dabagov et al. M.: SIMK, 2014. 112 p.</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Маммология. Национальное руководство. Под ред. В.П. Харченко, Н.И. Рожковой. М.: ГЭОТАР-Медиа, 2009. 328 с.</mixed-citation><mixed-citation xml:lang="en">Маммология. Национальное руководство. Под ред. В.П. Харченко, Н.И. Рожковой. М.: ГЭОТАР-Медиа, 2009. 328 с.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Mammalogy. National leadership. Ed. V. P. Kharchenko, N. I. Rozhkova. M.: GEOTAR-Media, 2009. 328 p.</mixed-citation><mixed-citation xml:lang="en">Mammalogy. National leadership. Ed. V. P. Kharchenko, N. I. Rozhkova. M.: GEOTAR-Media, 2009. 328 p.</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Cho N. Ductographic Findings of Breast Cancer. N. Cho, W.K. Moon, S.Y. Chung et al. Korean J Radiol. 2005. Vol. 6 (1). P. 31–36.</mixed-citation><mixed-citation xml:lang="en">Cho N. Ductographic Findings of Breast Cancer. N. Cho, W.K. Moon, S.Y. Chung et al. Korean J Radiol. 2005. Vol. 6 (1). P. 31–36.</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Fuchsjäger M.H. Diagnostic management of nipple discharge. M. N. Fuchsjäger, M.O. Philipp, C. Loewe C et al. Wien Klin Wochenschr. 2003. Vol. 115 (2). P. 33–9.</mixed-citation><mixed-citation xml:lang="en">Fuchsjäger M.H. Diagnostic management of nipple discharge. M. N. Fuchsjäger, M.O. Philipp, C. Loewe C et al. Wien Klin Wochenschr. 2003. Vol. 115 (2). P. 33–9.</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Sarica O. Comparison of ductoscopy, galactography, and imaging modalities for the evaluation of intraductal Lesions: A Critical Review. O. Sarica, E. Ozturk, H.C. Demirkurek et al. Breast Care (Basel). 2013. Vol. 8 (5). P. 348–354.</mixed-citation><mixed-citation xml:lang="en">Sarica O. Comparison of ductoscopy, galactography, and imaging modalities for the evaluation of intraductal Lesions: A Critical Review. O. Sarica, E. Ozturk, H.C. Demirkurek et al. Breast Care (Basel). 2013. Vol. 8 (5). P. 348–354.</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Wyss P. Papillary lesions of the breast: outcomes of 156 patients managed without excisional biopsy. P. Wyss, Z. Varga, M. Rossle et al. CJ. Breast J. 2014. No. 20. P. 394–401.</mixed-citation><mixed-citation xml:lang="en">Wyss P. Papillary lesions of the breast: outcomes of 156 patients managed without excisional biopsy. P. Wyss, Z. Varga, M. Rossle et al. CJ. Breast J. 2014. No. 20. P. 394–401.</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Рожкова Н.И., Бурдина И.И., Запирова С.Б., Лабазанова П. Г., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э. Многоликость непальпируемого рака молочной железы. Своевременная диагностика, адекватное лечение и профилактика Медицинский алфавит. Диагностика и онкотерапия. № 38. 2020; 34–40.</mixed-citation><mixed-citation xml:lang="en">Рожкова Н.И., Бурдина И.И., Запирова С.Б., Лабазанова П. Г., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э. Многоликость непальпируемого рака молочной железы. Своевременная диагностика, адекватное лечение и профилактика Медицинский алфавит. Диагностика и онкотерапия. № 38. 2020; 34–40.</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Rozhkova N.I., Burdina I.I., Zapirova S.B., Labazanova P.G., Mazo M.L., Mikushin S. Yu., Prokopenko S.P., Jacobs O. E. The diversity of non-palpable breast cancer. Timely diagnosis, adequate treatment and prevention Medical Alphabet. Diagnostics and oncotherapy. No. 38. 2020; 34–40.</mixed-citation><mixed-citation xml:lang="en">Rozhkova N.I., Burdina I.I., Zapirova S.B., Labazanova P.G., Mazo M.L., Mikushin S. Yu., Prokopenko S.P., Jacobs O. E. The diversity of non-palpable breast cancer. Timely diagnosis, adequate treatment and prevention Medical Alphabet. Diagnostics and oncotherapy. No. 38. 2020; 34–40.</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Муйжнек Е.Л., Киселёв В.И., Якобс О.Э., Рожкова Н.И., Каприн А.Д., Бурдина И.И., Запирова С.Б., Мазо М.Л., Прокопенко С.П., Лабазанова П. Г. Эпигенетическое перепрограммирование при фибросклерозе с микрокальцинатами в молочной железе. Своевременная диагностика и лечение (последн. 25.2.19).</mixed-citation><mixed-citation xml:lang="en">Муйжнек Е.Л., Киселёв В.И., Якобс О.Э., Рожкова Н.И., Каприн А.Д., Бурдина И.И., Запирова С.Б., Мазо М.Л., Прокопенко С.П., Лабазанова П. Г. Эпигенетическое перепрограммирование при фибросклерозе с микрокальцинатами в молочной железе. Своевременная диагностика и лечение (последн. 25.2.19).</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Muyzhnek E.L., Kiselev V.I., Yakobs O.E., Rozhkova N.I., Kaprin A.D., Burdina I.I., Zapirova S.B., Mazo M.L., Prokopenko S.P., Labazanova P.G. Epigenetic reprogramming in fibrosclerosis with microcalcifications in the mammary gland. Timely Diagnosis and Treatment (last 25.2.19).</mixed-citation><mixed-citation xml:lang="en">Muyzhnek E.L., Kiselev V.I., Yakobs O.E., Rozhkova N.I., Kaprin A.D., Burdina I.I., Zapirova S.B., Mazo M.L., Prokopenko S.P., Labazanova P.G. Epigenetic reprogramming in fibrosclerosis with microcalcifications in the mammary gland. Timely Diagnosis and Treatment (last 25.2.19).</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Якобс О.Э., Кудинова Е.А., Рожкова Н.И., Боженко В.К. Радиологические технологии и биогенетические маркеры в дифференциальной диагностике заболеваний молочной железы, сопровождающихся скоплениями микрокальцинатов. Вестник РНЦРР. 2017. http://vestnik.rncrr.ru/vestnik/v17/docs/yakobs.pdf</mixed-citation><mixed-citation xml:lang="en">Якобс О.Э., Кудинова Е.А., Рожкова Н.И., Боженко В.К. Радиологические технологии и биогенетические маркеры в дифференциальной диагностике заболеваний молочной железы, сопровождающихся скоплениями микрокальцинатов. Вестник РНЦРР. 2017. http://vestnik.rncrr.ru/vestnik/v17/docs/yakobs.pdf</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Jacobs O.E., Kudinova E.A., Rozhkova N.I., Bozhenko V.K. Radiological technologies and biogenetic markers in the differential diagnosis of breast diseases accompanied by accumulations of microcalcifications. Bulletin of Russian Scientific Center for Roentgen Radiology. 2017. http://vestnik.rncrr.ru/vestnik/v17/docs/yakobs.pdf</mixed-citation><mixed-citation xml:lang="en">Jacobs O.E., Kudinova E.A., Rozhkova N.I., Bozhenko V.K. Radiological technologies and biogenetic markers in the differential diagnosis of breast diseases accompanied by accumulations of microcalcifications. Bulletin of Russian Scientific Center for Roentgen Radiology. 2017. http://vestnik.rncrr.ru/vestnik/v17/docs/yakobs.pdf</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Cote ML, Ruterbusch JJ, Alosh B, Bandyopadhyay S, Kim E, Albashiti B, et al. Benign breast disease and the risk of subsequent breast cancer in African American women. Cancer Prev Res. 2012; 5 (12): 1375–80. DOI: https://doi.org/10.1158/1940–6207.CAPR‑12–0175</mixed-citation><mixed-citation xml:lang="en">Cote ML, Ruterbusch JJ, Alosh B, Bandyopadhyay S, Kim E, Albashiti B, et al. Benign breast disease and the risk of subsequent breast cancer in African American women. Cancer Prev Res. 2012; 5 (12): 1375–80. DOI: https://doi.org/10.1158/1940–6207.CAPR‑12–0175</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Visscher DW, Nassar A, Degnim AC. Frost MH, Vierkant RA, Frank RD, et al. Sclerosing adenosis and risk of breast cancer. Breast Cancer Res Treat. 2014; 144: 205–12. DOI: 10.1007/s10549–014–2862–5.</mixed-citation><mixed-citation xml:lang="en">Visscher DW, Nassar A, Degnim AC. Frost MH, Vierkant RA, Frank RD, et al. Sclerosing adenosis and risk of breast cancer. Breast Cancer Res Treat. 2014; 144: 205–12. DOI: 10.1007/s10549–014–2862–5.</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Castells X, Domingo L, Corominas JM, Torá-Rocamora I, Quintana MJ, Baré M, et al. Breast cancer risk after diagnosis by screening mammography of nonproliferative or proliferative benign breast disease: a study from a population-based screening program. Breast Cancer Res Treat. 2015; 149 (1): 237–44. DOI: 10.1007/s10549–014–3208-z.</mixed-citation><mixed-citation xml:lang="en">Castells X, Domingo L, Corominas JM, Torá-Rocamora I, Quintana MJ, Baré M, et al. Breast cancer risk after diagnosis by screening mammography of nonproliferative or proliferative benign breast disease: a study from a population-based screening program. Breast Cancer Res Treat. 2015; 149 (1): 237–44. DOI: 10.1007/s10549–014–3208-z.</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Ghasemi M, Nabipour I, Omrani A, Alipour Z, Assadi M. Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis. Am J Nucl Med Mol Imaging 2016; 6 (6): 310–327. Medline, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Ghasemi M, Nabipour I, Omrani A, Alipour Z, Assadi M. Precision medicine and molecular imaging: new targeted approaches toward cancer therapeutic and diagnosis. Am J Nucl Med Mol Imaging 2016; 6 (6): 310–327. Medline, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Рожкова Н. И., Боженко В. К., Бурдина И. И., Запирова С. Б., Лабазанова П. Г., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э. Радиогеномика рака молочной железы – новый вектор междисциплинарной интеграции лучевых и молекулярно-биологических технологий (обзор). Медицинский алфавит. Диагностика и онкотерапия. 2020; № 20, 21–29.</mixed-citation><mixed-citation xml:lang="en">Рожкова Н. И., Боженко В. К., Бурдина И. И., Запирова С. Б., Лабазанова П. Г., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э. Радиогеномика рака молочной железы – новый вектор междисциплинарной интеграции лучевых и молекулярно-биологических технологий (обзор). Медицинский алфавит. Диагностика и онкотерапия. 2020; № 20, 21–29.</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Rozhkova N.I., Bozhenko V.K., Burdina I.I., Zapirova S.B., Labazanova P.G., Mazo M.L., Mikushin S. Yu., Prokopenko S.P., Jacobs O.E. Radiogenomics of breast cancer – a new vector of interdisciplinary integration of radiation and molecular biological technologies (review). Medical Alphabet. Diagnostics and oncotherapy. 2020; No. 20, 21–29.</mixed-citation><mixed-citation xml:lang="en">Rozhkova N.I., Bozhenko V.K., Burdina I.I., Zapirova S.B., Labazanova P.G., Mazo M.L., Mikushin S. Yu., Prokopenko S.P., Jacobs O.E. Radiogenomics of breast cancer – a new vector of interdisciplinary integration of radiation and molecular biological technologies (review). Medical Alphabet. Diagnostics and oncotherapy. 2020; No. 20, 21–29.</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Кудинова Е.А., Рожкова Н.И., Кулинич Т.М., Захаренко М.В., Джикия Е.Л., Боженко В.К. Интеграция радиологических и молекулярно-биологических технологий обследования женщин сзаболеваниями молочных желез. Вестник РНЦРР, 2020, Том 20, № 1. Ссылка на статью: http://vestnik.rncrr.ru/vestnik/v20/docs/kudinova_t1.pdf</mixed-citation><mixed-citation xml:lang="en">Кудинова Е.А., Рожкова Н.И., Кулинич Т.М., Захаренко М.В., Джикия Е.Л., Боженко В.К. Интеграция радиологических и молекулярно-биологических технологий обследования женщин сзаболеваниями молочных желез. Вестник РНЦРР, 2020, Том 20, № 1. Ссылка на статью: http://vestnik.rncrr.ru/vestnik/v20/docs/kudinova_t1.pdf</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Kudinova E.A., Rozhkova N.I., Kulinich T.M., Zakharenko M.V., Jikia E.L., Bozhenko V.K. Integration of radiological and molecular biological technologies for examination of women with breast diseases. Bulletin of the Russian Scientific Center for Roentgen Radiology, 2020, Volume 20, No. 1. Link to the article: http://vestnik.rncrr.ru/vestnik/v20/docs/kudinova_t1.pdf</mixed-citation><mixed-citation xml:lang="en">Kudinova E.A., Rozhkova N.I., Kulinich T.M., Zakharenko M.V., Jikia E.L., Bozhenko V.K. Integration of radiological and molecular biological technologies for examination of women with breast diseases. Bulletin of the Russian Scientific Center for Roentgen Radiology, 2020, Volume 20, No. 1. Link to the article: http://vestnik.rncrr.ru/vestnik/v20/docs/kudinova_t1.pdf</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med 2015; 372 (9): 793–795. Crossref, Medline, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med 2015; 372 (9): 793–795. Crossref, Medline, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">European Society of Radiology (ESR). Medical imaging in personalised medicine: A white paper of the research committee of the European Society of Radiology (ESR). Insights Imaging 2015; 6 (2): 141–155. Crossref, Medline, Google Scholar</mixed-citation><mixed-citation xml:lang="en">European Society of Radiology (ESR). Medical imaging in personalised medicine: A white paper of the research committee of the European Society of Radiology (ESR). Insights Imaging 2015; 6 (2): 141–155. Crossref, Medline, Google Scholar</mixed-citation></citation-alternatives></ref><ref id="cit88"><label>88</label><citation-alternatives><mixed-citation xml:lang="ru">Kichko K, Marschall P, Flessa S. Personalized medicine in the U.S. and Germany: awareness, acceptance, use and preconditions for the wide implementation into the medical standard. J Pers Med 2016; 6 (2): E15. Crossref, Medline, Google Scholar</mixed-citation><mixed-citation xml:lang="en">Kichko K, Marschall P, Flessa S. Personalized medicine in the U.S. and Germany: awareness, acceptance, use and preconditions for the wide implementation into the medical standard. J Pers Med 2016; 6 (2): E15. Crossref, Medline, Google Scholar</mixed-citation></citation-alternatives></ref><ref id="cit89"><label>89</label><citation-alternatives><mixed-citation xml:lang="ru">Yamamoto S, Maki DD, Korn RL, Kuo MD. AJR Am J Roentgenol 2012; 199 (3): 654–663.</mixed-citation><mixed-citation xml:lang="en">Yamamoto S, Maki DD, Korn RL, Kuo MD. AJR Am J Roentgenol 2012; 199 (3): 654–663.</mixed-citation></citation-alternatives></ref><ref id="cit90"><label>90</label><citation-alternatives><mixed-citation xml:lang="ru">Рожкова Н.И., Боженко В.К., Бурдина И.И., Запирова С.Б., Кудинова Е.А., Лабазанова П.Г., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э. Радиогеномика рака молочной железы – новый вектор междисциплинарной интеграции лучевых и молекулярно-биологических технологий (обзор). Медицинский алфавит. Диагностика и онкотерапия. 2020; № 20, 21–29.</mixed-citation><mixed-citation xml:lang="en">Рожкова Н.И., Боженко В.К., Бурдина И.И., Запирова С.Б., Кудинова Е.А., Лабазанова П.Г., Мазо М.Л., Микушин С.Ю., Прокопенко С.П., Якобс О.Э. Радиогеномика рака молочной железы – новый вектор междисциплинарной интеграции лучевых и молекулярно-биологических технологий (обзор). Медицинский алфавит. Диагностика и онкотерапия. 2020; № 20, 21–29.</mixed-citation></citation-alternatives></ref><ref id="cit91"><label>91</label><citation-alternatives><mixed-citation xml:lang="ru">Rozhkova N.I., Bozhenko V.K., Burdina I.I., Zapirova S.B., Kudinova E.A., Labazanova P.G., Mazo M.L., Mikushin S. Yu., Prokopenko S.P., Jacobs O.E. Radiogenomics of breast cancer – a new vector of interdisciplinary integration of radiation and molecular biological technologies (review). Medical Alphabet. Diagnostics and oncotherapy. 2020; No. 20, 21–29.</mixed-citation><mixed-citation xml:lang="en">Rozhkova N.I., Bozhenko V.K., Burdina I.I., Zapirova S.B., Kudinova E.A., Labazanova P.G., Mazo M.L., Mikushin S. Yu., Prokopenko S.P., Jacobs O.E. Radiogenomics of breast cancer – a new vector of interdisciplinary integration of radiation and molecular biological technologies (review). Medical Alphabet. Diagnostics and oncotherapy. 2020; No. 20, 21–29.</mixed-citation></citation-alternatives></ref><ref id="cit92"><label>92</label><citation-alternatives><mixed-citation xml:lang="ru">Pinker K, Shitano F, Sala E et al. Background, J Magn Reson Imaging 2017 Nov 2 [Epub ahead of print]. Zhu Y, Li H, Guo W et al. Sci Rep 2015; 5 (1): 17787; Li H, Zhu Y, Burnside ES et al., Radiology. 2016; 281 (2): 382–391.</mixed-citation><mixed-citation xml:lang="en">Pinker K, Shitano F, Sala E et al. Background, J Magn Reson Imaging 2017 Nov 2 [Epub ahead of print]. Zhu Y, Li H, Guo W et al. Sci Rep 2015; 5 (1): 17787; Li H, Zhu Y, Burnside ES et al., Radiology. 2016; 281 (2): 382–391.</mixed-citation></citation-alternatives></ref><ref id="cit93"><label>93</label><citation-alternatives><mixed-citation xml:lang="ru">Бусько Е.А., Гончарова А.Б., Рожкова Н.И., Семиглазов В.В., Шишова А.С., Жильцова Е., Зиновьева Г., Белобородова К., Криворотько П.В. Модель системы принятия диагностических решений на основе мультипараметрических ультразвуковых показателей образований молочной железы. Вопросы онкологии. 2020; Т. 66, 653–658.</mixed-citation><mixed-citation xml:lang="en">Бусько Е.А., Гончарова А.Б., Рожкова Н.И., Семиглазов В.В., Шишова А.С., Жильцова Е., Зиновьева Г., Белобородова К., Криворотько П.В. Модель системы принятия диагностических решений на основе мультипараметрических ультразвуковых показателей образований молочной железы. Вопросы онкологии. 2020; Т. 66, 653–658.</mixed-citation></citation-alternatives></ref><ref id="cit94"><label>94</label><citation-alternatives><mixed-citation xml:lang="ru">Busko E.A., Goncharova A.B., Rozhkova N.I., Semiglazov V.V., Shishova A.S., Zhiltsova E., Zinovieva G., Beloborodova K., Krivorotko P.V. Model of a diagnostic decision-making system based on multiparametric ultrasound indicators of breast formations. Issues of Oncology. 2020; T. 66, 653–658.</mixed-citation><mixed-citation xml:lang="en">Busko E.A., Goncharova A.B., Rozhkova N.I., Semiglazov V.V., Shishova A.S., Zhiltsova E., Zinovieva G., Beloborodova K., Krivorotko P.V. Model of a diagnostic decision-making system based on multiparametric ultrasound indicators of breast formations. Issues of Oncology. 2020; T. 66, 653–658.</mixed-citation></citation-alternatives></ref><ref id="cit95"><label>95</label><citation-alternatives><mixed-citation xml:lang="ru">Yamamoto S, Han W, Kim Y et al. Breast cancer: radiogenomic biomarker reveals associations among dynamic contrast-enhanced MR imaging, long noncoding RNA, and metastasis. Radiology 2015; 275 (2): 384–392. Link, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Yamamoto S, Han W, Kim Y et al. Breast cancer: radiogenomic biomarker reveals associations among dynamic contrast-enhanced MR imaging, long noncoding RNA, and metastasis. Radiology 2015; 275 (2): 384–392. Link, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit96"><label>96</label><citation-alternatives><mixed-citation xml:lang="ru">Ashraf AB, Daye D, Gavenonis S et al. Identification of intrinsic imaging phenotypes for breast cancer tumors: preliminary associations with gene expression profiles. Radiology 2014; 272 (2): 374–384. Link, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Ashraf AB, Daye D, Gavenonis S et al. Identification of intrinsic imaging phenotypes for breast cancer tumors: preliminary associations with gene expression profiles. Radiology 2014; 272 (2): 374–384. Link, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit97"><label>97</label><citation-alternatives><mixed-citation xml:lang="ru">Yamamoto S, Maki DD, Korn RL, Kuo MD. Radiogenomic analysis of breast cancer using MRI: a preliminary study to define the landscape. AJR Am J Roentgenol 2012; 199 (3): 654–663. Crossref, Medline, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Yamamoto S, Maki DD, Korn RL, Kuo MD. Radiogenomic analysis of breast cancer using MRI: a preliminary study to define the landscape. AJR Am J Roentgenol 2012; 199 (3): 654–663. Crossref, Medline, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit98"><label>98</label><citation-alternatives><mixed-citation xml:lang="ru">Li H, Zhu Y, Burnside ES et al. MR Imaging radiomics signatures for predicting the risk of breast cancer recurrence as given by research versions of MammaPrint, Oncotype DX, and PAM50 gene assays. Radiology 2016; 281 (2): 382–391. Link, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Li H, Zhu Y, Burnside ES et al. MR Imaging radiomics signatures for predicting the risk of breast cancer recurrence as given by research versions of MammaPrint, Oncotype DX, and PAM50 gene assays. Radiology 2016; 281 (2): 382–391. Link, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit99"><label>99</label><citation-alternatives><mixed-citation xml:lang="ru">Waugh SA, Purdie CA, Jordan LB et al. Magnetic resonance imaging texture analysis classification of primary breast cancer. Eur Radiol 2016; 26 (2): 322–330. Crossref, Medline, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Waugh SA, Purdie CA, Jordan LB et al. Magnetic resonance imaging texture analysis classification of primary breast cancer. Eur Radiol 2016; 26 (2): 322–330. Crossref, Medline, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit100"><label>100</label><citation-alternatives><mixed-citation xml:lang="ru">Clark K, Vendt B, Smith K et al. The Cancer Imaging Archive (TCIA): maintaining and operating a public information repository. J Digit Imaging 2013; 26 (6): 1045–1057. Crossref, Medline, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Clark K, Vendt B, Smith K et al. The Cancer Imaging Archive (TCIA): maintaining and operating a public information repository. J Digit Imaging 2013; 26 (6): 1045–1057. Crossref, Medline, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit101"><label>101</label><citation-alternatives><mixed-citation xml:lang="ru">Yamaguchi K, Abe H, Newstead GM et al. Intratumoral heterogeneity of the distribution of kinetic parameters in breast cancer: comparison based on the molecular subtypes of invasive breast cancer. Breast Cancer 2015; 22 (5): 496–502. Crossref, Medline, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Yamaguchi K, Abe H, Newstead GM et al. Intratumoral heterogeneity of the distribution of kinetic parameters in breast cancer: comparison based on the molecular subtypes of invasive breast cancer. Breast Cancer 2015; 22 (5): 496–502. Crossref, Medline, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit102"><label>102</label><citation-alternatives><mixed-citation xml:lang="ru">Alyass A, Turcotte M, Meyre D. From big data analysis to personalized medicine for all: challenges and opportunities. BMC Med Genomics 2015; 8 (1): 33. Crossref, Medline, Google Scholar.</mixed-citation><mixed-citation xml:lang="en">Alyass A, Turcotte M, Meyre D. From big data analysis to personalized medicine for all: challenges and opportunities. BMC Med Genomics 2015; 8 (1): 33. Crossref, Medline, Google Scholar.</mixed-citation></citation-alternatives></ref><ref id="cit103"><label>103</label><citation-alternatives><mixed-citation xml:lang="ru">Рожкова Н.И., Ройтберг П. Г., Варфоломеев А.А., Мазо М.Л., Добренький Д.Н., Блинов Д.С., Сушков Е.В., Дерябина О.Н, Соколов А.И. Сегментационная модель скрининга рака молочной железы на основе нейросетевого анализа рентгеновских изображений. Сеченовский вестник. 2020; Том 11, № 3, 4–14.</mixed-citation><mixed-citation xml:lang="en">Рожкова Н.И., Ройтберг П. Г., Варфоломеев А.А., Мазо М.Л., Добренький Д.Н., Блинов Д.С., Сушков Е.В., Дерябина О.Н, Соколов А.И. Сегментационная модель скрининга рака молочной железы на основе нейросетевого анализа рентгеновских изображений. Сеченовский вестник. 2020; Том 11, № 3, 4–14.</mixed-citation></citation-alternatives></ref><ref id="cit104"><label>104</label><citation-alternatives><mixed-citation xml:lang="ru">Rozhkova N.I., Roitberg P.G., Varfolomeev A.A., Mazo M.L., Dobrenkiy D.N., Blinov D.S., Sushkov E.V., Deryabina O.N., Sokolov A. AND. Segmentation model of breast cancer screening based on neural network analysis of x-ray images. Sechenovskiy Bulletin. 2020; Vol. 11, No. 3, 4–14.</mixed-citation><mixed-citation xml:lang="en">Rozhkova N.I., Roitberg P.G., Varfolomeev A.A., Mazo M.L., Dobrenkiy D.N., Blinov D.S., Sushkov E.V., Deryabina O.N., Sokolov A. AND. Segmentation model of breast cancer screening based on neural network analysis of x-ray images. Sechenovskiy Bulletin. 2020; Vol. 11, No. 3, 4–14.</mixed-citation></citation-alternatives></ref><ref id="cit105"><label>105</label><citation-alternatives><mixed-citation xml:lang="ru">Якобс О.Э. Ранняя диагностика непальпируемого рака молочной железы на основе интеграции цифровых радиологических технологий. Диссертация насоискание учёной степени доктора медицинских наук 14.01.12, 14.01.13, защищена 19.02.2019, Москва, 2018.</mixed-citation><mixed-citation xml:lang="en">Якобс О.Э. Ранняя диагностика непальпируемого рака молочной железы на основе интеграции цифровых радиологических технологий. Диссертация насоискание учёной степени доктора медицинских наук 14.01.12, 14.01.13, защищена 19.02.2019, Москва, 2018.</mixed-citation></citation-alternatives></ref><ref id="cit106"><label>106</label><citation-alternatives><mixed-citation xml:lang="ru">Jacobs O.E. Early diagnosis of non-palpable breast cancer based on the integration of digital radiological technologies. Thesis for the degree of Doctor of Medical Sciences 01/14/12, 01/14/13, defended 02/19/2019, Moscow, 2018.</mixed-citation><mixed-citation xml:lang="en">Jacobs O.E. Early diagnosis of non-palpable breast cancer based on the integration of digital radiological technologies. Thesis for the degree of Doctor of Medical Sciences 01/14/12, 01/14/13, defended 02/19/2019, Moscow, 2018.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
