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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2022-29-13-19</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2898</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Гигантоклеточный артериит в условиях коронавирусной инфекции (клиническое наблюдение)</article-title><trans-title-group xml:lang="en"><trans-title>Giant cell arteritis in conditions of coronavirus infection (clinical case)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7588-8089</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабаева</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Babaeva</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бабаева Аида Руфатовна - доктор медицинских наук, проф., зав. кафедрой факультетской терапии.</p><p>Волгоград</p></bio><bio xml:lang="en"><p>Babaeva Aida R. - DM Sci, professor, head of Dept of Faculty Therapy.</p><p>Volgograd</p></bio><email xlink:type="simple">arbabaeva@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3061-1254</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лекарева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lekareva</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лекарева Ирина Владимировна - кандидат медицинских наук, доцент, доцент кафедры факультетской терапии.</p><p>Волгоград</p></bio><bio xml:lang="en"><p>Lekareva Irina V. - PhD Med, associate professor, associate professor at Dept of Faculty Therapy.</p><p>Volgograd</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1762-6056</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калинина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalinina</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Калинина Елена Валерьевна - кандидат медицинских наук, доцент, доцент кафедры факультетской терапии.</p><p>Волгоград</p></bio><bio xml:lang="en"><p>Kalinina Elena V. - PhD Med, associate professor, associate professor at Dept of Faculty Therapy.</p><p>Volgograd</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5335-9151</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Звоноренко</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvonorenko</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Звоноренко Максим Сергеевич - ассистент кафедры факультетской терапии.</p><p>Волгоград</p></bio><bio xml:lang="en"><p>Zvonorenko Maksim S., assistant at Dept of Faculty Therapy.</p><p>Volgograd</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Волгоградский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Volgograd State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>25</day><month>12</month><year>2022</year></pub-date><volume>0</volume><issue>29</issue><issue-title>Ревматология в общей врачебной практике (2)</issue-title><fpage>13</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бабаева А.Р., Лекарева И.В., Калинина Е.В., Звоноренко М.С., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Бабаева А.Р., Лекарева И.В., Калинина Е.В., Звоноренко М.С.</copyright-holder><copyright-holder xml:lang="en">Babaeva A.R., Lekareva I.V., Kalinina E.V., Zvonorenko M.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2898">https://www.med-alphabet.com/jour/article/view/2898</self-uri><abstract><p>Сложность своевременной диагностики гигантоклеточного артериита (ГКА), как наиболее частой формы системного васкулита у лиц пожилого возраста, обусловлена неспецифичностью клинических проявлений и отсутствием специфических иммунологических маркеров. Новые трудности возникают в период коронавирусной инфекции, которая проявляется сходными синдромами и в то же время может спровоцировать иммуновоспалительное ревматическое заболевание. В связи с этим чрезвычайно важно провести корректный дифференциальный диагноз между персистирующей вирусной инфекцией и развитием системного васкулита. В настоящей статье приведено клиническое наблюдение, демонстрирующее сложный процесс диагностики и дифференциальной диагностики ГКА в условиях пандемии COVID-19. Пациентка была госпитализирована в связи с подтвержденной коронавирусной инфекцией. Однако, несмотря на проведенную стандартную терапию и достигнутую эрадикацию коронавируса, сохранялись симптомы, характерные для ГКА и ревматической полимиалгии (РП). Детальный анализ клинической картины позволил установить, что типичные для ГКА и РП проявления возникли в период, предшествовавший инфицированию COVID-19. Последующее углубленное обследование позволило верифицировать диагноз ГКА и РП на основании действующих классификационных критериев. Проведенная терапия глюкокортикоидами и метотрексатом позволила достигнуть ремиссии. Представленное наблюдение позволит повысить информированность врачей общей практики и представителей других специальностей о необходимости исключения ГКА и РП в случае длительной немотивированной лихорадки, миалгий, цефалгий, суставного синдрома, преходящих нарушений зрения, болей в нижней челюсти у пациентов пожилого возраста, перенесших коронавирусную инфекцию.</p></abstract><trans-abstract xml:lang="en"><p>The complexity of timely diagnosis of giant cell arteritis (GCA), as the most common form of systemic vasculitis in the elderly, is due to the nonspecificity of clinical manifestations and the absence of specific immunological markers. New difficulties arise during the period of coronavirus infection, which manifests itself in similar syndromes and at the same time can provoke immuno-inflammatory rheumatic disease. In this regard, it is extremely important to make a correct differential diagnosis between persistent viral infection and the development of systemic vasculitis. This article presents a clinical observation demonstrating the complex process of diagnosis and differential diagnosis of GCA in the conditions of the COVID-19 pandemic. The patient was hospitalized due to a confirmed coronavirus infection. However, despite the standard therapy and the achieved eradication of the coronavirus, the symptoms characteristic of GCA and polymyalgia rheumatica (PR) persisted. A precision analysis of the clinical picture allowed us to establish that the typical manifestations of GCA and PR occurred in the period preceding COVID-19 infection. Subsequent in-depth examination made it possible to verify the diagnosis of GCA and PR based on the current classification criteria. The therapy with glucocorticoid and methotrexate made it possible to achieve remission. The presented observation will help to raise awareness of general practitioners and related specialties about the need to rule out GCA and PR in the case of prolonged unexplained fever, myalgia, headache, joint pain and swelling, transient visual disturbances, jaw claudication in elderly patients in the setting or after coronavirus infection.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гигантоклеточный артериит</kwd><kwd>ревматическая полимиалгия</kwd><kwd>коронавирусная инфекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>giant cell arteritis</kwd><kwd>rheumatic polymyalgia</kwd><kwd>coronavirus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бунчук Н. В. Ревматические заболевания пожилых. Н. В. Бунчук. М.: Медпресс, 2014. 136 с.</mixed-citation><mixed-citation xml:lang="en">Bunchuk N. V. Rheumatic diseases of the elderly. N. V. Bunchuk. 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