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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2022-25-34-40</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2855</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Дефицит железа и постковидный синдром: клинический случай</article-title><trans-title-group xml:lang="en"><trans-title>Iron deficiency and postcovid syndrome: a clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0491-8823</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полякова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Polyakova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полякова Ольга Александровна, кандидат медицинских наук, ассистент кафедры терапии и полиморбидной патологии имени академика М.С. Вовси</p><p>Москва </p></bio><bio xml:lang="en"><p>Polyakova Olga A., Cand. Sci. (Med.), assistant of the Department of Therapy and Polymorbid Pathology named after academician M.S. Vovsi</p><p>Moscow </p></bio><email xlink:type="simple">docpolyakova.olga@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4258-1889</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клепикова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Klepikova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клепикова Мария Викторовна, кандидат медицинских наук, доцент кафедры терапии и полиморбидной патологии имени академика М.С. Вовси</p><p>Москва</p></bio><bio xml:lang="en"><p>Klepikova Mariya V., Cand. Sci. (Med.), Associate Professor of the Department of Therapy and Polymorbid Pathology named after academician M.S. Vovsi</p><p>Moscow </p></bio><email xlink:type="simple">pelageam@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2546-1340</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долдо</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Doldo</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Долдо Николай Михайлович, врач-кардиолог, заведующий терапевтическим отделением</p><p>Москва</p></bio><bio xml:lang="en"><p>Doldo Nikolay M., cardiologist, head of the therapeutic department</p><p>Moscow</p></bio><email xlink:type="simple">Kolj.spb@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7614-2836</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаакян</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaakian</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Исаакян Юрий Арсенович, студент 5-го курса, персонализированная медицина</p><p>Москва</p></bio><bio xml:lang="en"><p>Isaakyan Yuri A., 5th year student, Personalized medicine</p><p>Moscow</p></bio><email xlink:type="simple">yuri.isaakyan@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0795-8225</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Остроумова</surname><given-names>О. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostroumova</surname><given-names>O. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Остроумова Ольга Дмитриевна, доктор медицинских наук, профессор, заведующая кафедрой терапии и полиморбидной патологии имени академика М.С. Вовси</p><p>Москва</p></bio><bio xml:lang="en"><p>Ostroumova Olga D., Dr. Sci. (Med.), Professor, Head of the Department of Therapy and Polymorbid Pathology named after academician M.S. Vovsi</p><p>Moscow</p></bio><email xlink:type="simple">ostroumova.olga@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Частное учреждение здравоохранения «Центральная клиническая больница «РЖД-Медицина»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Private healthcare institution «Central clinical hospital of the medicine of the Russian Railways»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» Минздрава России (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The State Education Institution of Higher Professional Training The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>25</day><month>11</month><year>2022</year></pub-date><volume>0</volume><issue>25</issue><issue-title>Современная поликлиника (2)</issue-title><fpage>34</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Полякова О.А., Клепикова М.В., Долдо Н.М., Исаакян Ю.А., Остроумова О.Д., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Полякова О.А., Клепикова М.В., Долдо Н.М., Исаакян Ю.А., Остроумова О.Д.</copyright-holder><copyright-holder xml:lang="en">Polyakova O.A., Klepikova M.V., Doldo N.M., Isaakian Y.A., Ostroumova O.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2855">https://www.med-alphabet.com/jour/article/view/2855</self-uri><abstract><p>Постковидный синдром – это серьезная проблема общественного здравоохранения, затрагивающая миллионы людей по всему миру. В настоящее время накапливается все больше сведений о том, что у людей могут проявляться симптомы после повреждения органов, развившегося во время острой фазы COVID‑19, в то время как другие испытывают новые симптомы после легкой инфекции, без каких-либо признаков приобретенного повреждения органов или тканей. В связи с этим понимание детерминант и регуляторов патологии COVID‑19 и постковидного синдрома является важной клинической задачей, решение которой даст возможность лучше справляться с будущими вариантами и волнами пандемии. Предполагается, что между гомеостазом железа, COVID‑19 и постковидным синдромом существует тесная взаимосвязь, патогенетические аспекты которой еще предстоит определить. Тем не менее в имеющейся литературе уже есть данные, указывающие на то, что дефицит железа и железодефицитная анемия (без анемии воспаления) у пациентов с постковидным синдромом встречается в 30 и 9% случаев соответственно. Учитывая, важность и актуальность данной проблемы и то, что каждый третий пациент с постковидным синдромом может иметь дефицит железа, в данной статье приводится случай из клинический практики, в котором у пациентки с постковидным синдромом был выявлен дефицит железа и железодефицитная анемия, а лечение данного состояния и заболевания привело к улучшению общего самочувствия и регрессированию симптоматики. Таким образом, последствия от COVID‑19 на обмен железа существуют, и они могут поддаваться коррекции. Применение пероральных препаратов железа, в частности, препарата сульфата железа, позволяет добиться оптимального терапевтического и клинического эффектов в данной клинической ситуации наряду с хорошей переносимостью и профилем безопасности.</p></abstract><trans-abstract xml:lang="en"><p>Postcovid syndrome is a serious public health problem affecting millions of people worldwide. There is a growing body of evidence that people may exhibit symptoms after organ damage developed during the acute phase of COVID‑19, while others experience new symptoms after a mild infection, without any evidence of acquired organ or tissue damage. In this regard, understanding the determinants and regulators of COVID‑19 and postcovid syndrome pathology is an important clinical challenge that will enable better management of future variants and pandemic waves. There is presumably a close relationship between iron homeostasis, COVID‑19, and postcovid syndrome, the pathogenetic aspects of which have yet to be determined. Nevertheless, the available literature already indicates that iron deficiency and iron deficiency anemia (without inflammatory anemia) in patients with postcovid syndrome occur in 30% and 9% of cases, respectively. Given the importance and urgency of this problem and the fact that one in three patients with postcovid syndrome may have iron deficiency, this article presents a case from clinical practice in which a patient with postcovid syndrome was found to have iron deficiency and iron deficiency anemia, and treatment of this condition and disease resulted in improvement in general well-being and regression of symptoms. Thus, the effects of COVID‑19 on iron metabolism exist, and they can be corrected. The use of oral iron preparations, in particular iron sulfate, allows optimal therapeutic and clinical effects in this clinical situation along with a good tolerability and safety profile.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID 19</kwd><kwd>постковидный синдром</kwd><kwd>дефицит железа</kwd><kwd>железодефицитная анемия</kwd><kwd>сульфат железа</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID 19</kwd><kwd>postcovid syndrome</kwd><kwd>iron deficiency</kwd><kwd>iron deficiency anemia</kwd><kwd>iron sulfate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Рекомендации по ведению больных с коронавирусной инфекцией COVID 19 в острой фазе и при постковидном синдроме в амбулаторных условиях / под ред. профессор П.А. 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