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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2022-18-45-47</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2764</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Частота встречаемости синдрома колоректальной брадиаритмии у пожилых пациентов</article-title><trans-title-group xml:lang="en"><trans-title>Frequency of occurrence of colorectal bradyarrhythmia syndrome in elderly patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5623-4226</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селиверстов</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Seliverstov</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Селиверстов Павел Васильевич, к.м.н., доцент 2-й кафедры (терапии усовершенствования врачей)</p><p> Санкт-Петербург </p></bio><bio xml:lang="en"><p> Seliverstov Pavel V., PhD Med, associate professor at the 2nd Dept (of Therapy for Advanced Training) </p><p> Saint Petersburg </p></bio><email xlink:type="simple">seliverstov-pv@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2785-6699</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванюк</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanyuk</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Иванюк Елена Сергеевна, к.м.н., ст. преподаватель 2-й кафедры (терапии усовершенствования врачей)</p><p> Санкт-Петербург </p></bio><bio xml:lang="en"><p> Ivanyuk Elena S., PhD Med, senior lecturer of the 2nd Dept (of Therapy for Advanced Training) </p><p> Saint Petersburg </p></bio><email xlink:type="simple">gastroperm@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кантемирова</surname><given-names>Р. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kantemirova</surname><given-names>R. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Кантемирова Раиса Кантемировна, д.м.н., проф. кафедры госпитальной терапии</p><p>Санкт-Петербург </p></bio><bio xml:lang="en"><p> Kantemirova Raisa K., DM Sci (habil.), professor at Dept of Hospital Therapy </p><p>Saint Petersburg</p></bio><email xlink:type="simple">terapium@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2889-3042</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шемеровский</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shemerovsky</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Шемеровский Константин Александрович, д.м.н., проф., с.н.с. </p><p>Санкт-Петербург </p></bio><bio xml:lang="en"><p> Konstantin Aleksandrovich Sh., DM Sci (habil.), professor, senior researcher </p><p>Saint Petersburg</p></bio><email xlink:type="simple">constshem@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБВОУ ВО «Военно-медицинская академия имени С.М. Кирова» Минобороны России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Military Medical Academy n.a. S.M. Kirov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ЧОУ ВО «Санкт-Петербургский медико-социальный институт»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg Medical and Social University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>24</day><month>09</month><year>2022</year></pub-date><volume>1</volume><issue>18</issue><issue-title>Практическая гастроэнтерология (2)</issue-title><fpage>45</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Селиверстов П.В., Иванюк Е.С., Кантемирова Р.К., Шемеровский К.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Селиверстов П.В., Иванюк Е.С., Кантемирова Р.К., Шемеровский К.А.</copyright-holder><copyright-holder xml:lang="en">Seliverstov P.V., Ivanyuk E.S., Kantemirova R.K., Shemerovsky K.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2764">https://www.med-alphabet.com/jour/article/view/2764</self-uri><abstract><p>Одной из ключевых проблем современной медицины является синдром брадиэнтерии, который проявляется замедлением циркадианного ритма энтеральной эвакуаторной функции при частоте дефекации реже семи раз в неделю. С позиций хронобиологии и хрономедицины, регулярность циркадианного ритма дефекации является таким же околосуточным ритмом организма, как регулярность цикла «сон – бодрствование». Однако хронофизиологический механизм регулярности ритма кишечника и частота ее встречаемости среди лиц разного возраста остаются мало изученными. Показанный в нашей работе хронофизиологический механизм нарушения регулярности циркадианного ритма дефекации указывает на необходимость соблюдения не только частоты, но и утренней акрофазы этого ритма для профилактики множества осложнений, возникающих на основе брадиэнтерии у пациентов с хроническим запором.</p></abstract><trans-abstract xml:lang="en"><p>One of the key problems of modern medicine is the bradienteria syndrome, which is manifested by a slowdown in the circadian rhythm of the enteral evacuation function at a frequency of defecation less than 7 times a week. From the standpoint of chronobiology and chronomedicine, the regularity of the circadian rhythm of defecation is the same circadian rhythm of the body as the regularity of the sleep-wake cycle. However, the chronophysiological mechanism of the regularity of the intestinal rhythm and the frequency of its occurrence among people of different ages remains poorly understood. The chronophysiological mechanism of violation of the regularity of the circadian rhythm of defecation shown in our work indicates the need to observe not only the frequency, but also the morning acrophase of this rhythm for the prevention of many complications arising from bradienteria in patients with chronic constipation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальная брадиаритмия</kwd><kwd>запоры</kwd><kwd>ритм</kwd><kwd>слабительные</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colorectal bradiarrhythmia</kwd><kwd>constipation</kwd><kwd>rhythm</kwd><kwd>laxatives</kwd><kwd>prevention.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аверин Е.Е. Фарматека. 2010; № 10: 56–59.</mixed-citation><mixed-citation xml:lang="en">Averin E.E. 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