medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2022-17-50-61medalphabet-2750Research ArticleСтатьиАсинхронии при респираторной поддержкеAsynchronies during respiratory supportКорякинА. Г.KoryakinA. G.

Альберт Геннадьевич Корякин, врач-ординатор

ГБУЗ «Городская клиническая больница имени С. П. Боткина Департамента здравоохранения Москвы»

отделение реанимации

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»

Москва

Albert G. Koryakin,  intern in Intensive

Care Unit

Moscow

koriakinalbert@gmail.comhttps://orcid.org/0000-0003-4535-2563ВласенкоА. В.VlasenkoA. V.

Алексей Викторович Власенко, д. м. н., лауреат Премии правительства РФ в области науки и техники, зав. отделением

ГБУЗ «Городская клиническая больница имени С. П. Боткина Департамента здравоохранения Москвы»

отделение реанимации

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»

Москва

Scopus ID: 7006740682

Alexey V. Vlasenko, DM Sci (habil.), Laureate of the Prize of the Government ofthe Russian Federation in the field of science and technology, head of Unit

Intensive Care Unit

Moscow

dr.vlasenko67@mail.ruРодионовЕ. П.RodionovE. P.

Евгений Петрович Родионов, к. м. н., зам. гл. врача по анестезиологии и реанимации

ГБУЗ «Городская клиническая больница имени С. П. Боткина Департамента здравоохранения Москвы»

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»

Москва

Evgeny P. Rodionov, PhD Med, deputy chief physician for anesthesiology andresuscitation

Moscow

dr.rodionov@gmail.comЕвдокимовЕ. А.EvdokimovE. A.

Евгений Александрович Евдокимов, д. м. н., проф., заслуженный врач РФ, зав. кафедрой

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»

кафедра анестезиологии и неотложной медицины

Москва

Evgeny A. Evdokimov, DM Sci (habil.), professor, Honored Doctor of the RussianFederation, head of Dept;  adviser to the rector 

Dept of Anesthesiology and Emergency Medicine 

Moscow

ea_evdokimov@mail.ruДепартамент здравоохранения Москвы; Минздрав РоссииРоссияCity Clinical Hospital n. a. S. P. Botkin; Russian Medical Academy for Continuing Professional EducationRussian FederationМинздрав РоссииРоссияRussian Medical Academy for Continuing Professional EducationRussian Federation202208092022017Кардиология. Неотложная медицина (2)5061Copyright © Корякин А.Г., Власенко А.В., Родионов Е.П., Евдокимов Е.А., 20222022Корякин А.Г., Власенко А.В., Родионов Е.П., Евдокимов Е.А.Koryakin A.G., Vlasenko A.V., Rodionov E.P., Evdokimov E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/2750

   Асинхронии (десинхронии, диссинхронии) представляют собой нарушение гармоничного взаимодействия дыхательной системы пациента и аппарата искусственной вентиляции легких. Асинхронии возникают в результате разных причин и при любых видах респираторной поддержки (не инвазивная, инвазивная вспомогательная или полностью контролируемая искусственная вентиляция легких). Асинхронии являются значимыми причинами нарушения биомеханики и газообмена в легких, развития самоповреждения и вентилятор-индуцированного повреждения легких, увеличения продолжительности респираторной поддержки и роста летальности пациентов с дыхательной недостаточностью. Понимание механизмов патогенеза асинхроний и оценка состояния респираторной системы пациента позволяют своевременно выявить и устранить нарушения взаимодействия пациента с респиратором. В работе представлены классификация, основные причины развития, методы диагностики и способы коррекции разных вариантов десинхроний у пациентов с дыхательными расстройствами в условиях респираторной поддержки.

   Asynchronies (desynchronies, dyssynchrony) is a disturbance of the harmonious interaction between the patient’s respiratory system and а ventilator. Asynchronies occur as a result of various reasons and with any form of respiratory support (non-invasive, assisted or fully controlled mechanical ventilation). Asynchrony is a significant cause of biomechanics and gas exchange disorders in the development of both self-injury and ventilator-induced lung injury, an increase of the respiratory support duration and mortality in patients with respiratory failure. Understanding the mechanisms of the asynchrony pathogenesis and assessment of the patient’s respiratory system condition make it possible to timely identify and resolve disturbance of the patient-ventilator interactions. The article presents a classification, the main causes of development, diagnostic and correction methods of different variants of desynchronies in patients with respiratory disorders during of respiratory support.

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The authors declare that there are no conflicts of interest present.