medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2022-16-102-108medalphabet-2739Research ArticleМИКРОНУТРИЕНТЫ И МИНЕРНЫЕ ВЕЩЕСТВА: НОВОЕ И АКТУАЛЬНОЕВитамин К2: известный и неизвестный. Современный взгляд: возможности и перспективыVitamin K2: known and unknown. Modern view: opportunities and prospectshttps://orcid.org/0000-0003-3220-0333НикитинаЕ. А.NikitinaE. A.

Никитина Елена Александровна, к. м. н., доцент кафедры диетологии и клинической нутрициологии

Москва

Nikitina Elena A., PhD Med, assistant professor of Dept of Dietetics and Clinical Nutritiology

Moscow

nikitina-ea1@rudn.ruhttps://orcid.org/0000-0002-4689-3591ОрловаС. В.OrlovaS. V.

Орлова Светлана Владимировна, д. м. н., профессор, заведующая кафедрой диетологии и клинической нутрициологии

Москва

Orlova Svetlana V., DM Sci (habil.), professor, head of Dept of Dietetics and Clinical Nutritiology

Moscow

orlova-sv@rudn.ruhttps://orcid.org/0000-0001-8744-2976МагомедоваХ. А.MagomedovaKh. A.

Магомедова Хадижат Абдулхаликовна, ассистент кафедры диетологии и клинической нутрициологии

Москва

Magomedova Khadizhat A., assistant of Dept of Dietetics and Clinical Nutritiology

Moscow

hadiga28@mail.ruhttps://orcid.org/0000-0002-0548-3414БалашоваН. В.BalashovaN. V.

Балашова Наталья Валерьевна, к. б. н., ассистент доцент кафедры диетологии и клинической нутрициологии

Москва

Balashova Natalya V., PhD Bio Sci, assistant of Dept of Dietetics and Clinical Nutritiology

Moscow

balashovaN77@mail.ruhttps://orcid.org/0000-0002-3811-9459ПрокопенкоЕ. В.ProkopenkoE. V.

Прокопенко Елена Валерьевна, врач-эндокринолог, диетолог, ведущий менеджер проектов медицинского департамента

Москва

Prokopenko Elena V., endocrinologist, dietitian, Project Manager of Medical Department

Moscow

elvprokopenko@gmail.comhttps://orcid.org/0000-0002-5203-1082ВодолазкаяА. Н.VodolazkayaA. N.

Водолазкая Ангелина Николаевна, врач-диетолог

Москва

Vodolazkaya Angelina N., dietitian

Moscow

drvodolazkaya@gmail.comhttps://orcid.org/0000-0002-5250-5911ПронинаО. Е.ProninaO. E.

Пронина Олеся Евгеньевна, врач эндокринолог, диетолог, гинеколог

Москва

Pronina Olesya E., endocrinologist, nutritionist, gynecologist

Moscow

pronina.doctor@yandex.ruФГАОУ ВО «Российский университет дружбы народов» (РУДН)РоссияРeoples Friendship University of Russia (RUDN University)Russian FederationООО «ИНВИТРО»РоссияInvitro Co.Russian FederationАвстрийская клиника микронутриентной терапии BiogenaРоссияAustrian Clinic of micronutrient therapy BiogenaRussian FederationКлиника «Медгород»РоссияMedical center «Medgorod»Russian Federation202202092022016Диетология и нутрициология (1)102108Copyright © Никитина Е.А., Орлова С.В., Магомедова Х.А., Балашова Н.В., Прокопенко Е.В., Водолазкая А.Н., Пронина О.Е., 20222022Никитина Е.А., Орлова С.В., Магомедова Х.А., Балашова Н.В., Прокопенко Е.В., Водолазкая А.Н., Пронина О.Е.Nikitina E.A., Orlova S.V., Magomedova K.A., Balashova N.V., Prokopenko E.V., Vodolazkaya A.N., Pronina O.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/2739

В настоящее время витамин К2 является одним из наиболее популярных микронутриентов как у исследователей, так и у практикующих врачей. Помимо хорошо известного участия в синтезе факторов свертывания, витамин К2 оказывает влияние на отложение кальция в костной ткани и внекостных структурах, защищая от развития остеопороза и кальцификации сосудов. За последние годы накапливается все больше данных о его участии в регуляции ключевых физиологических и патологических процессов в организме, таких как деление и дифференцировка клеток, углеводный обмен, воспаление, оксидативный стресс и др. В настоящем обзоре мы разбираем источники витамина К2, механизмы его действия и влияние на метаболизм.

Currently vitamin K2 is one of the most popular micronutrients among both researchers and practitioners. In addition to its well-known role in the synthesis of coagulation factors, vitamin K2 regulates the deposition of calcium in bone and soft tissues, protecting against the development of osteoporosis and vascular calcification. In recent years, more and more data have been accumulated on its participation in the regulation of key physiological and pathological processes in the body, such as cell division and differentiation, carbohydrate metabolism, inflammation, oxidative stress, etc. In this review, we analyze the sources of vitamin K2, the mechanisms of its action and influence on metabolism.

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The authors declare that there are no conflicts of interest present.