medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2022-8-75-78medalphabet-2609Research ArticleВ ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУЧувствительная кожа: что за этим стоит и как помочь пациентам?Sensitive skin: What is behind it and how to help patients?https://orcid.org/0000-0003-2027-5987СаканияЛ. Р.SakaniyaL. R.

 Сакания Луиза Руслановна, м.н.с.1, врач-дерматолог

 Sakaniya Luiza R., junior researcher, dermatologist 

sakania.luiz@yandex.ruОленичИ. В.OlenichI. V.

 Оленич Ирина Владимировна, врач-дерматолог, зав. отделением дневного стационара 

 Olenich Irina V., dermatologist, head of Day Hospital Dept 

https://orcid.org/0000-0002-6583-0318КорсунскаяИ. М.KorsunskayaI. M.

 Корсунская Ирина Марковна, д.м.н., проф., зав. лаб.

 Korsunskaya Irina M., DM Sci (habil.), professor, head of laboratory 

marykor@bk.ruФГБУН «Центр теоретических проблем физико-химической фармакологии» Российской академии наук; ГБУЗ «Московский научно-практический центр дерматовенерологии и косметологии Департамента здравоохранения Москвы»РоссияCentre for Theoretical Problems of Physicochemical Pharmacology; Moscow Research and Practical Centre for Dermatovenereology and CosmetologyRussian FederationГБУЗ «Московский научно-практический центр дерматовенерологии и косметологии Департамента здравоохранения Москвы»РоссияMoscow Research and Practical Centre for Dermatovenereology and CosmetologyRussian FederationФГБУН «Центр теоретических проблем физико-химической фармакологии» Российской академии наукРоссияCentre for Theoretical Problems of Physicochemical PharmacologyRussian Federation20221805202208Дерматология (1)7578Copyright © Сакания Л.Р., Оленич И.В., Корсунская И.М., 20222022Сакания Л.Р., Оленич И.В., Корсунская И.М.Sakaniya L.R., Olenich I.V., Korsunskaya I.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/2609

Чувствительная кожа – довольно распространенное состояние, встречающееся примерно у половины населения в целом. Данное состояние характеризуется рядом неприятных кожных симптомов (покалывание, жжение, боль, зуд), возникающих в ответ на раздражители, которые обычно не вызывают таких реакций. У пациентов с чувствительной кожей зачастую наблюдается и выраженная сухость кожных покровов. На сегодняшний день облегчение состояния чувствительной сухой кожи сводится к использованию увлажняющих средств ухода. Нами было проведено исследование клинической эффективности линейки увлажняющих средств LE SANTI®, в котором приняли участие 50 волонтеров. Как показывают данные исследования, значимый эффект достигается к 21-му дню использования увлажняющих средств, однако длительное применение более 2 месяцев позволяет достичь максимального значения увлажнения и сохранить нормальные значения корнеометрических показателей кожи даже после прекращения использования средств.

Sensitive skin is a common condition, affecting about half of the general population. This condition is characterized by a number of unpleasant skin symptoms (tingling, burning, pain, and itching) that occur in response to triggers that usually do not cause such reactions. Severe dryness of the skin is often observed in patients with sensitive skin. Nowadays, treatment of the condition of sensitive dry skin comes down to the use of moisturizing care products. We conducted a study of the clinical effectiveness of moisturizing products, which included 50 volunteers. According to the study data, a signifcant effect was achieved by the 21st day of using moisturizers. However, long-term use for more than 2 months allowed to maintain normal values of corneometric parameters even after cancelation moisturizers.

чувствительная кожасухая кожаувлажняющие средствауход за кожейкорнеометрические показатели кожиsensitive skindry skinmoisturizersskin carecorneometric parametersReferencesPons-Guiraud A. Sensitive skin: A complex and Multifactorial syndrome. J Cosmet Dermatol 2005; 3: 145–8.Pons-Guiraud A. Sensitive skin: A complex and Multifactorial syndrome. J Cosmet Dermatol 2005; 3: 145–8.MuizzuddinN., Marenus K.D.,Maes D.H. Factors defning sensitive skin and its treatment. Am J Contact Dermat 1998; 9: 170–5.MuizzuddinN., Marenus K.D.,Maes D.H. Factors defning sensitive skin and its treatment. Am J Contact Dermat 1998; 9: 170–5.Frosch P.J., Kligman A.M. A method of apraising the stinging capacity of topically applied substances. J Soc Cosmet Chem 1977; 28: 197–209.Frosch P.J., Kligman A.M. A method of apraising the stinging capacity of topically applied substances. J Soc Cosmet Chem 1977; 28: 197–209.Berardesca E., Fluhr J.W., Maibach H.I. What is sensitive skin? In: Berardesca E, Fluhr JW, Maibach HI, editors. Sensitive Skin Syndrome. New York: Taylor & Francis; 2006. p. 1–6.Berardesca E., Fluhr J.W., Maibach H.I. What is sensitive skin? In: Berardesca E, Fluhr JW, Maibach HI, editors. Sensitive Skin Syndrome. New York: Taylor & Francis; 2006. p. 1–6.Misery L., Ständer S., Szepietowski J.C., Reich A., Wallengren J., Evers A.W.M., et al. Defnition of sensitive skin: an expert position paper from the special interest group on sensitive skin of the International Forum for the Study of Itch. Acta Derm Venereol 2017; 97: 4–6. DOI: https: //doi.org/10.2340/00015555–2397Misery L., Ständer S., Szepietowski J.C., Reich A., Wallengren J., Evers A.W.M., et al. Defnition of sensitive skin: an expert position paper from the special interest group on sensitive skin of the International Forum for the Study of Itch. Acta Derm Venereol 2017; 97: 4–6. DOI: https: //doi.org/10.2340/00015555–2397Misery L., Myon E., Martin N., Verrière F., Nocera T., Taieb C. Peaux sensibles en France: approche épidémiologique. Ann Dermatol Venereol 2005; 132: 425–429. DOI: https: //doi.org/10.1016/S0151–9638(05)79303–0Misery L., Myon E., Martin N., Verrière F., Nocera T., Taieb C. Peaux sensibles en France: approche épidémiologique. Ann Dermatol Venereol 2005; 132: 425–429. DOI: https: //doi.org/10.1016/S0151–9638(05)79303–0Chen W., Dai R., Li L. The prevalence of self-declared sensitive skin: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol 2020; 34: 1779–1788. DOI: https://doi.org/10.1111/jdv.16166Chen W., Dai R., Li L. The prevalence of self-declared sensitive skin: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol 2020; 34: 1779–1788. DOI: https://doi.org/10.1111/jdv.16166Willis C.M., Shaw S., Lacharriere O.D., Baverel M., Reiche L., Jourdain R., et al. Sensitive skin: An epidemiological study. Br J Dermatol 2001; 145: 258–63.Willis C.M., Shaw S., Lacharriere O.D., Baverel M., Reiche L., Jourdain R., et al. Sensitive skin: An epidemiological study. Br J Dermatol 2001; 145: 258–63.Loffler H., Aramaki J., Effendy I., Maibach H. Sensitive skin. In: Zhai H., Maibach H., editors. Dermatotoxicology. New York: CRC Press; 2004. p. 123–35.Loffler H., Aramaki J., Effendy I., Maibach H. Sensitive skin. In: Zhai H., Maibach H., editors. Dermatotoxicology. New York: CRC Press; 2004. p. 123–35.Richters R., Falcone D., Uzunbajakava N., Verkruysse W., van Erp P., van de Kerkhof P. What is sensitive skin? A systematic literature review of objective measurements. Skin Pharmacol Physiol. 2015; 28: 75–83.Richters R., Falcone D., Uzunbajakava N., Verkruysse W., van Erp P., van de Kerkhof P. What is sensitive skin? A systematic literature review of objective measurements. Skin Pharmacol Physiol. 2015; 28: 75–83.Pedro P., Catarina R., Catarina P., Monteiro R.L. Is there any barrier impairment in sensitive skin? A quantitative analysis of sensitive skin by mathematical modeling of transepidermal water loss desorption curves. Skin Res Technol 2011; 17: 181–5.Pedro P., Catarina R., Catarina P., Monteiro R.L. Is there any barrier impairment in sensitive skin? A quantitative analysis of sensitive skin by mathematical modeling of transepidermal water loss desorption curves. Skin Res Technol 2011; 17: 181–5.Misery L., Sibaud V., Merial-Kieny C., Taieb C. Sensitive skin in the American population: prevalence, clinical data, and role of the dermatologist. Int J Dermatol 2011; 50: 961–967. DOI: https://doi.org/10.1111/j.1365–4632.2011.04884.xMisery L., Sibaud V., Merial-Kieny C., Taieb C. Sensitive skin in the American population: prevalence, clinical data, and role of the dermatologist. Int J Dermatol 2011; 50: 961–967. DOI: https://doi.org/10.1111/j.1365–4632.2011.04884.xMisery L., Jourdan E., Huet F., Brenaut E., Cadars B., Virassamynaïk S., et al. Sensitive skin in France: a study on prevalence, relationship with age and skin type and impact on quality of life. J Eur Acad Dermatol Venereol 2018; 32: 791–795. DOI: https: //doi.org/10.1111/jdv.14837Misery L., Jourdan E., Huet F., Brenaut E., Cadars B., Virassamynaïk S., et al. Sensitive skin in France: a study on prevalence, relationship with age and skin type and impact on quality of life. J Eur Acad Dermatol Venereol 2018; 32: 791–795. DOI: https: //doi.org/10.1111/jdv.14837Farage M.A., Katsarou A., Maibach H.I. Sensory, clinical and physiological factors in sensitive skin: a review. Contact Dermatitis 2006; 55: 1–14. DOI: https://doi.org/10.1111/j.0105–1873.2006.00886Farage M.A., Katsarou A., Maibach H.I. Sensory, clinical and physiological factors in sensitive skin: a review. Contact Dermatitis 2006; 55: 1–14. DOI: https://doi.org/10.1111/j.0105–1873.2006.00886Legeas C., Misery L., Fluhr J.W., Roudot A.C., Ficheux A.S., Brenaut E. Proposal for Cut-off Scores for Sensitive Skin on Sensitive Scale-10in a Group of Adult Women. Acta Derm Venereol.2021 Jan 13; 101 (1): adv00373. DOI: 10.2340/00015555–3741.Legeas C., Misery L., Fluhr J.W., Roudot A.C., Ficheux A.S., Brenaut E. Proposal for Cut-off Scores for Sensitive Skin on Sensitive Scale-10in a Group of Adult Women. Acta Derm Venereol.2021 Jan 13; 101 (1): adv00373. DOI: 10.2340/00015555–3741.Tominaga M., Ozawa S., Tengara S., Ogawa H., Takamori K. Intraepidermal nerve fibers increase in dry skin of acetone-treated mice. J Dermatol Sci 2007; 48: 103–111.Tominaga M., Ozawa S., Tengara S., Ogawa H., Takamori K. Intraepidermal nerve fibers increase in dry skin of acetone-treated mice. J Dermatol Sci 2007; 48: 103–111.Kuraishi Y. Methods for preclinical assessment of antipruritic agents and itch mechanisms independent of mast-cell histamine. Biol Pharm Bull 2015; 38: 635–644.Kuraishi Y. Methods for preclinical assessment of antipruritic agents and itch mechanisms independent of mast-cell histamine. Biol Pharm Bull 2015; 38: 635–644.Toncic R.J., Kezic S., Hadzavdic S.L., Marinovic B. Skin barrier and dry skin in the mature patient. Clin Dermatol 2018; 36: 109–115.Toncic R.J., Kezic S., Hadzavdic S.L., Marinovic B. Skin barrier and dry skin in the mature patient. Clin Dermatol 2018; 36: 109–115.Murota H., Katayama I. Exacerbating factors of itch in atopic dermatitis. Allergol Int 2017; 66: 8–13.Murota H., Katayama I. Exacerbating factors of itch in atopic dermatitis. Allergol Int 2017; 66: 8–13.Bohme M., Soderhall C., Kull I., Bergstrom A., van Hage M., Wahlgren C.F. Filaggrin mutations increase the risk for persistent dry skin and eczema independent of sensitization. J Allergy Clin Immunol 2012; 129: 1153–1155.Bohme M., Soderhall C., Kull I., Bergstrom A., van Hage M., Wahlgren C.F. Filaggrin mutations increase the risk for persistent dry skin and eczema independent of sensitization. J Allergy Clin Immunol 2012; 129: 1153–1155.Marron S.E., Tomas-Aragones L., Boira S., Campos-Rodenas R. Quality of life, emotional wellbeing and family repercussions in dermatological patients experiencing chronic itching: a pilot study. Acta Derm Venereol 2016; 96: 331–335.Marron S.E., Tomas-Aragones L., Boira S., Campos-Rodenas R. Quality of life, emotional wellbeing and family repercussions in dermatological patients experiencing chronic itching: a pilot study. Acta Derm Venereol 2016; 96: 331–335.França K. Topical Probiotics in Dermatological Therapy and Skincare: A Concise Review. Dermatol Ther (Heidelb). 2021; 11 (1): 71–77. DOI: 10.1007/s13555–020–00476–7.França K. Topical Probiotics in Dermatological Therapy and Skincare: A Concise Review. Dermatol Ther (Heidelb). 2021; 11 (1): 71–77. DOI: 10.1007/s13555–020–00476–7.

The authors declare that there are no conflicts of interest present.