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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2022-5-7-14</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2583</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Клинико-эпидемиологические характеристики нейроэндокринных опухолей ЖКТ на основе одноцентрового регистра</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and epidemiological features of neuroendocrine tumors on basis of single-centre registry</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7111-1507</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андросова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Androsova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андросова Александра Валерьевна, аспирант, врач-онколог отделения противоопухолевой лекарственной терапии № 10</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Androsova Aleksandra V., post-graduate student, medical oncologist of Cancer Drug Therapy (Chemotherapeutic) Dept No. 10</p><p> </p></bio><email xlink:type="simple">alexa.androsova.1711@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4447-9458</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орлова Рашида Вахидовна, д. м. н., проф., зав. кафедрой онкологии, гл. специалист по клинической онкологии</p><p>Санкт-Петербург</p><p>SPIN: 3480–2098</p><p>Author ID: 401170</p></bio><bio xml:lang="en"><p>Orlova Rashida V., DM Sci. (habil.), head of Chair for Oncology, chief specialist in Clinical Oncology</p><p>Saint Petersburg</p><p>SPIN: 3480–2098.</p><p>Author ID: 40117</p></bio><email xlink:type="simple">orlova_rashida@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0211-9809</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Анастасия Константиновна, врач-онколог отделения противоопухолевой лекарственной терапии № 11</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Ivanova Anastasia K., medical oncologist of Cancer Drug Therapy (Chemotherapeutic) Dept No. 11</p><p>Saint Petersburg</p></bio><email xlink:type="simple">oncolog.ivanova@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0402-6067</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беляк</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Belyak</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беляк Наталья Петровна, к. м. н., ассистент кафедры онкологии, зав. отделением противоопухолевой лекарственной терапии № 10</p><p>Санкт-Петербург</p><p>SPIN: 2937–4858</p><p>Author ID: 778562</p></bio><bio xml:lang="en"><p>Belyak Natalia P., PhD Med, associate professor at Dept of Oncology, head of Cancer Drug Therapy (Chemotherapeutic) Dept No. 10</p><p>Saint Petersburg</p><p>SPIN: 2937–4858</p><p>Author ID: 778562</p></bio><email xlink:type="simple">drnpb@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2221-4088</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кутукова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kutukova</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кутукова Светлана Игоревна, к. м. н., доцент кафедры стоматологии хирургической и челюстно-лицевой хирургии, врач-онколог отделения противоопухолевой лекарственной терапии № 10</p><p>Санкт-Петербург</p><p>SPIN: 6735–6556</p><p>Author ID: 698363</p></bio><bio xml:lang="en"><p>Kutukova Svetlana I., PhD Med, associate professor at Dept of Surgical and Maxillofacial Surgery Dentistry, medical oncologist of Cancer Drug Therapy (Chemotherapeutic) Dept No. 10</p><p>Saint Petersburg</p><p>SPIN: 6735–6556</p><p>Author ID: 698363</p></bio><email xlink:type="simple">dr.s.kutukova@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9628-7098</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каледина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaledina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каледина Екатерина Александровна, врач-онколог отделения противоопухолевой лекарственной терапии № 10</p><p>Санкт-Петербург</p><p>SPIN: 8925–3320</p><p>Author ID: 1020115</p></bio><bio xml:lang="en"><p>Kaledina Ekaterina A., medical oncologist of Cancer Drug Therapy (Chemotherapeutic) Dept No. 10</p><p>Saint Petersburg</p><p>SPIN: 8925–3320</p><p>Author ID: 1020115</p></bio><email xlink:type="simple">kate199595@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Санкт-Петербургский государственный университет»; СПб ГБУЗ «Городской клинический онкологический диспансер»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg State University; City Clinical Oncology Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>СПб ГБУЗ «Городской клинический онкологический диспансер»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Oncology Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>СПб ГБУЗ «Городской клинический онкологический диспансер»; 3ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Oncology Centre; First Saint Petersburg State Medical University n. a. I. P. Pavlov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>30</day><month>04</month><year>2022</year></pub-date><volume>1</volume><issue>5</issue><issue-title>Диагностика и онкотерапия (1)</issue-title><fpage>7</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Андросова А.В., Орлова Р.В., Иванова А.К., Беляк Н.П., Кутукова С.И., Каледина Е.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Андросова А.В., Орлова Р.В., Иванова А.К., Беляк Н.П., Кутукова С.И., Каледина Е.А.</copyright-holder><copyright-holder xml:lang="en">Androsova A.V., Orlova R.V., Ivanova A.K., Belyak N.P., Kutukova S.I., Kaledina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2583">https://www.med-alphabet.com/jour/article/view/2583</self-uri><abstract><p>Нейроэндокринные опухоли представляют собой гетерогенную группу злокачественных новообразований. Алгоритм назначения того или иного вида лечения, в том числе системного, зависит от степени дифференцировки и распространенности опухоли на основании классификации ВОЗ (2010) и рекомендаций Европейского общества по изучению нейроэндокринных опухолей (НЭО) (ENETS, 2011). Данная нозология является относительно редкой (заболеваемость – от 2 до 5 случаев на 100 тысяч человек). Однако за последние 30 лет отмечается рост числа заболеваний НЭО на 720 %, согласно данным регистра США SEER (Surveillance, Epidemiology, and End Results). В данной статье представлены результаты анализа клинико-эпидемиологических характеристик нейроэндокринных опухолей ЖКТ у пациентов, получавших лечение в СПб ГБУЗ «ГКОД».</p></abstract><trans-abstract xml:lang="en"><p>Neuroendocrine tumors (NET) are fairly heterogenous malignant tumors. The algorithm of choosing a particular type of treatment, including systemic therapy, depends on the degree of differentiation and tumor burden based on the WHO classification (2010) and the guidelines of the European Neuroendocrine Tumor Society (ENETS, 2011). This nosology is relatively rare (the incidence is 2 to 5 per 100 thousand population).</p><p>However, over the past 30 years, there has been an increase in the number of NET diseases by 720 % according to the US SEER (Surveillance, Epidemiology, and End Results) register. This article presents the results of the analysis of the clinical and epidemiological characteristics of neuroendocrine gastrointestinal tumors in patients treated in the St. Petersburg City Clinical Oncology Centre.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нейроэндокринная опухоль</kwd><kwd>нейроэндокринный рак</kwd><kwd>нейроэндокринные опухоли</kwd><kwd>аналоги соматостатина</kwd><kwd>регистр</kwd></kwd-group><kwd-group xml:lang="en"><kwd>neuroendocrine tumor</kwd><kwd>neuroendocrine cancer</kwd><kwd>neuroendocrine tumors</kwd><kwd>somatostatin analogs</kwd><kwd>registry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Yao J. C., Hassan M., Phan A., Dagohoy C. et al. One hundred years after ‘carcinoid’: epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States. J. Clin. Oncol. 2008. 26 (18). Р: 3063–3072. 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