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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-253</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Полипрагмазия или ЭСТ? Сравнительная характеристика побочных эффектов у больных с резистентной шизофренией</article-title><trans-title-group xml:lang="en"><trans-title>Polypharmacy or ECT? Side effects profile comparison in patients with resistant schizophrenia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зубов</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zubov</surname><given-names>D. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБУ «Национальный медицинский исследовательский центр психиатрии и неврологии имени В.М. Бехтерева» Минздрава России</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>09</day><month>07</month><year>2017</year></pub-date><volume>2</volume><issue>21</issue><issue-title>Больница — все для ЛПУ</issue-title><fpage>52</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зубов Д.С., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Зубов Д.С.</copyright-holder><copyright-holder xml:lang="en">Zubov D.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/253">https://www.med-alphabet.com/jour/article/view/253</self-uri><abstract><p>Работа посвящена анализу выраженности и частоты встречаемости побочных эффектов у пациентов, страдающих терапевтически резистентной шизофренией. При помощи шкалы UKU проведено сравнение спектра и степени выраженности побочных эффектов между двумя группами пациентов: получающих комплексную электросудорожную терапию (ЭСТ) и антипсихотики и только медикаментозное лечение. Выявлено, что у пациентов, получающих комплексную терапию ЭСТ и антипсихотиками, определенные группы побочных эффектов имеют меньшую степень выраженности и большую степень редукции в процессе терапии по сравнению с пациентами, получающими только медикаментозное лечение.</p></abstract><trans-abstract xml:lang="en"><p>The data about treatment resistant paranoid schizophrenia patients getting electroconvulsive therapy (ECT) together with antipsychotic agents and about the patients receiving combined antipsychotics treatment only is observed in the article. The side effects spectrum is analyzed with the help of UKU standardized scale. Patients getting combined ECT and antipsychotics treatment have less intensity and greater reduction of some specific side effects groups during the course of antipsychotic treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>электросудорожная терапия</kwd><kwd>антипсихотические средства</kwd><kwd>побочные эффекты</kwd><kwd>переносимость</kwd><kwd>безопасность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>electroconvulsive therapy</kwd><kwd>antipsychotic agents</kwd><kwd>side effects</kwd><kwd>tolerability</kwd><kwd>safety</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">McGrath J., Saha S., Chant D. et al. Schizophrenia: a concise overview of incidence, prevalence, and mortality. // Epidemiologic Reviews. - 2008. - Vol. 30. - P. 67-76.</mixed-citation><mixed-citation xml:lang="en">McGrath J., Saha S., Chant D. et al. 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