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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-249</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Влияние ожирения на содержание витамина D в сыворотке крови беременных</article-title><trans-title-group xml:lang="en"><trans-title>Influence of obesity on content of vitamin D in blood serum of pregnant women</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терехина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Teryokhina</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Падруль</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Padrul</surname><given-names>M. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>E. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБОУ ВО «Пермский государственный медицинский университет имени академика Е. А. Вагнера» Минздрава России</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ГБУЗ ПК «Медсанчасть № 9 имени М.А. Тверье»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>09</day><month>07</month><year>2017</year></pub-date><volume>2</volume><issue>21</issue><issue-title>Больница — все для ЛПУ</issue-title><fpage>37</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Терехина Н.А., Падруль М.М., Макарова Е.Л., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Терехина Н.А., Падруль М.М., Макарова Е.Л.</copyright-holder><copyright-holder xml:lang="en">Teryokhina N.A., Padrul M.M., Makarova E.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/249">https://www.med-alphabet.com/jour/article/view/249</self-uri><abstract><p>В сыворотке крови 65 беременных выявлен низкий уровень витамина D при ожирении. Самое значимое снижение наблюдалось при андроидном типе III степени ожирения в зимнее время года. Уменьшение биодоступности гормона D при увеличении жирового депо способствует развитию инсулинорезистентности, гестационного сахарного диабета и формированию значимых осложнений для матери и плода в результате срыва компенсаторных возможностей организма. Определение содержания витамина D в сыворотке крови беременных с ожирением имеет значение для прогнозирования осложнений матери и плода.</p></abstract><trans-abstract xml:lang="en"><p>In the blood serum of 65 pregnant women a low level of vitamin D in obesity was revealed. The most significant decrease was observed in the android type of grade 3 obesity in a winter season. Reduction of D hormone bioavailability with an increase in fat depot promotes the development of insulin resistance, gestational diabetes and the formation of significant complications for mother and fetus as a result of failure of the compensatory capacity of the organism. Determination of vitamin D in the blood serum of pregnant women with obesity is important for predicting complications of mother and fetus.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>витамин D</kwd><kwd>беременность</kwd><kwd>ожирение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vitamin D</kwd><kwd>pregnancy</kwd><kwd>obesity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Макарова Е.А., Терехина Н.А., Падруль М.М. Статус адипокинов в сыворотке крови беременных с ожирением / Клиническая лабораторная диагностика. - 2015. - № 9. - С. 61-62.</mixed-citation><mixed-citation xml:lang="en">Макарова Е.А., Терехина Н.А., Падруль М.М. Статус адипокинов в сыворотке крови беременных с ожирением / Клиническая лабораторная диагностика. - 2015. - № 9. - С. 61-62.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Макаров И.О., Боровкова Е.И. Течение беременности и родов у пациенток с ожирением / Акушерство и гинекология. - 2011. - № 1. - С. 23-28.</mixed-citation><mixed-citation xml:lang="en">Макаров И.О., Боровкова Е.И. Течение беременности и родов у пациенток с ожирением / Акушерство и гинекология. - 2011. - № 1. - С. 23-28.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Chen T.C., Holick M.F. et al. Factors that influence the cutaneous synthesis and dietary sources of vitamin D / Arch. Biochem. Biophys. - 2007. - Apr 15. - V. 460 (2). - P. 213-217.</mixed-citation><mixed-citation xml:lang="en">Chen T.C., Holick M.F. et al. Factors that influence the cutaneous synthesis and dietary sources of vitamin D / Arch. Biochem. Biophys. - 2007. - Apr 15. - V. 460 (2). - P. 213-217.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Calcium and Vitamin D / Washington, DC. - National Academy Press. - 2010.</mixed-citation><mixed-citation xml:lang="en">Institute of Medicine, Food and Nutrition Board. Dietary Reference Intakes for Calcium and Vitamin D / Washington, DC. - National Academy Press. - 2010.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Lewis S., Lucas R.M., Halliday J., Ponsonby A.L. Vitamin D deficiency and pregnancy: From preconception to birth / Molecular Nutrition and Food Research. - 2010. - V.54. - № 8. - P. 1092-1102.</mixed-citation><mixed-citation xml:lang="en">Lewis S., Lucas R.M., Halliday J., Ponsonby A.L. Vitamin D deficiency and pregnancy: From preconception to birth / Molecular Nutrition and Food Research. - 2010. - V.54. - № 8. - P. 1092-1102.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Liu N.Q., Kaplan A.T., Lagishetty V. et al. Vitamin D and the regulation of placental inflammation / Journal of Immunology. - 2011. - Vol. 186. - V. 10. - P. 5968-5974.</mixed-citation><mixed-citation xml:lang="en">Liu N.Q., Kaplan A.T., Lagishetty V. et al. Vitamin D and the regulation of placental inflammation / Journal of Immunology. - 2011. - Vol. 186. - V. 10. - P. 5968-5974.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Merewood A., Mehta S.D., Chen T.C., Bauchner H., Holick M.F. Association between vitamin D deficiency and primary cesarean section / Journal Clin. Endocrinol. Metab. - 2009. - V. 94 (3). - P. 940-945.</mixed-citation><mixed-citation xml:lang="en">Merewood A., Mehta S.D., Chen T.C., Bauchner H., Holick M.F. Association between vitamin D deficiency and primary cesarean section / Journal Clin. Endocrinol. Metab. - 2009. - V. 94 (3). - P. 940-945.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Ozturk C., Atamaz F.C., Akkurt H., Akkoc Y. Pregnancy-associated osteoporosis presenting severe vertebral fractures / Journal Obstet. Gynaecol. Res. - 2014. - Jan. - V. 40 (1).- P. 288-292.</mixed-citation><mixed-citation xml:lang="en">Ozturk C., Atamaz F.C., Akkurt H., Akkoc Y. Pregnancy-associated osteoporosis presenting severe vertebral fractures / Journal Obstet. Gynaecol. Res. - 2014. - Jan. - V. 40 (1).- P. 288-292.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Wortsman J., Matsuoka L.Y., Chen T.C., Lu Z., Holick M.F. Decreased bioavailability of vitamin D in obesity / American Journal of Clinical Nutrition. - 2000. - V. 72 (3). - P. 690-693.</mixed-citation><mixed-citation xml:lang="en">Wortsman J., Matsuoka L.Y., Chen T.C., Lu Z., Holick M.F. Decreased bioavailability of vitamin D in obesity / American Journal of Clinical Nutrition. - 2000. - V. 72 (3). - P. 690-693.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
