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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2021-41-20-26</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2417</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБОЗРЕНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>«Долгий ковид» (постковидный синдром): механизм возникновения, диагностика и реабилитация</article-title><trans-title-group xml:lang="en"><trans-title>‘Long Covid’ (post-covid syndrome): Mechanism of occurrence, diagnosis and rehabilitation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чой</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Choi</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чой Ен Джун, д.м.н., врач высшей категории, главный врач</p><p>Москва</p></bio><bio xml:lang="en"><p>Choi Yong Joon, DM Sci (habil.), physician of superior expert category, chief physician of the Centre</p><p>Moscow</p></bio><email xlink:type="simple">info@drchoi.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Центр европейской и восточной медицины (ООО «Доктор Чой»)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Centre of European and Oriental Medicine (‘Dr. Choi’ Co.)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>09</day><month>01</month><year>2022</year></pub-date><volume>0</volume><issue>41</issue><issue-title>Обозрение (1)</issue-title><fpage>20</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чой Е.Д., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Чой Е.Д.</copyright-holder><copyright-holder xml:lang="en">Choi E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2417">https://www.med-alphabet.com/jour/article/view/2417</self-uri><abstract><p>Статья посвящена изучению актуальной проблемы современного человечества–борьбе с пандемией, вызванной новой коронавирусной инфекцией, а именно изучению механизма развития «долгого ковида» (постковидного синдрома), новому клинико-лабораторному методу его диагностики, вопросам лекарственной и немедикаментозной реабилитации пациентов, перенесших COVID‑19. В работе описывается этиопатогенез постковидного синдрома (ПС), отличительными особенностями которого является поражение сердечно-сосудистой, дыхательной, нервной, пищеварительной, иммунной систем организма, ЛОР-органов и опорно-двигательного аппарата. Для диагностики постковидного синдрома впервые в РФ апробирован монохромный анализатор наночастиц (МАН), позволяющий определять патофизиологические сдвиги в системе гомеостаза. Установлено, что метод МАН имеет высокую диагностическую чувствительность (78%), а сдвиги в системе гомеостаза при постковидном синдроме являются статистически значимыми (р &lt; 0,001). Принципиально важным моментом данного исследования является то, что разработан алгоритм неинвазивной диагностики ПС по слюне (ротоглоточным смывам), основанный на обнаружении высокого вклада в рассеяние лазерного излучения в среднечастотном диапазоне спектра на наночастицах размером от 119 до 121 нм. Также особое внимание в статье уделяется лекарственным и немедикаментозным методам лечения пациентов с «долгим ковидом», испытывающих на себе последствия перенесенной новой коронавирусной инфекции. Установлено, что наилучший эффект оказывает комплексное лечение, сочетающее методы традиционной европейской школы (медикаментозная терапия с применением сердечно-сосудистых препаратов, ноотропных средств, хондропротекторов, витаминов и минеральных комплексов, гормонов, гепатопротекторов, биостимуляторов, седативных и противовоспалительных средств и других препаратов) и немедикаментозные методы восстановительного лечения, практикуемые восточной медициной (иглорефлексотерапия, гирудотерапия, массаж, остеопатия и т.д.).</p></abstract><trans-abstract xml:lang="en"><p>The article is devoted to the study of an urgent problem of modern humanity – the fight against a pandemic caused by a new coronavirus infection, namely: the study of the mechanism of development of ‘long Covid’ (post-covid syndrome), a new clinical and laboratory method of its diagnosis, issues of drug and non-drug rehabilitation of patients who have suffered COVID‑19. The paper describes the etiopathogenesis of post-covid syndrome (PS), the distinctive features of which are the defeat of the cardiovascular, respiratory, nervous, digestive, immune systems of the body, ENT organs and musculoskeletal system. For the diagnosis of post-covid syndrome, a monochrome nanoparticle analyzer (MAN) has been tested for the first time in the Russian Federation, which allows determining pathophysiological shifts in the homeostasis system. It was found that the MAN method has a sufficiently high diagnostic sensitivity (78%), and shifts in the homeostasis system in post-covid syndrome are statistically significant (p &lt; 0.001). A fundamentally important point of this study is that an algorithm has been developed for noninvasive diagnosis of PS by saliva (oropharyngeal flushes), based on the detection of a high contribution to the scattering of laser radiation in the mid-frequency range of the spectrum on nanoparticles ranging in size from 119 to 121 nm. The article also pays special attention to medicinal and non-medicinal methods of treatment of patients with ‘long Covid’ experiencing the consequences of a new coronavirus infection. It has been established that the best effect is provided by complex treatment combining methods of the traditional European school (drug therapy with the use of cardiovascular drugs, nootropic agents, chondroprotectors, vitamins and mineral complexes, hormones, hepatoprotectors, biostimulants, sedatives and anti-inflammatory drugs and other drugs) and non-drug methods of restorative treatment practiced by Oriental medicine (acupuncture, hirudotherapy, massage, osteopathy, etc.).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID‑19</kwd><kwd>«долгий ковид»</kwd><kwd>постковидный синдром</kwd><kwd>монохромный анализ наночастиц</kwd><kwd>диагностика</kwd><kwd>лечение</kwd><kwd>реабилитация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID‑19</kwd><kwd>‘long Covid’</kwd><kwd>post-covid syndrome</kwd><kwd>monochrome analysis of nanoparticles</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd><kwd>rehabilitation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Покровский ВИ, Киселев ОИ, Назаров ПГ. 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