medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2021-35-48-51medalphabet-2360Research ArticleСТОМАТОЛОГИЯDENTISTRYРоль адипокинов в регуляции моторной активности толстой кишки у лиц с избыточной массой тела и ожирениемRole of adipokines in regulation of colonic motor activity in overweight and obese individualshttps://orcid.org/0000-0002-0238-4664ФедоринМ. М.FedorinМ. М.

Федорин Максим Михайлович - ординатор кафедры факультетской терапии и гастроэнтерологии, инспектор управления по развитию регионального здравоохранения и медицинской деятельности

Fedorin Maksim M. - resident at Dept of Faculty Therapy and Gastroenterology

mail.maxim.f@gmail.comhttps://orcid.org/0000-0002-6581-7017ЛивзанМ. А.LivzanM. A.

Ливзан Мария Анатольевна - доктор медицинских наук, профессор, ректор, зав. кафедрой факультетской терапии и гастроэнтерологии

Livzan Maria A. - DM Sci (habil.), professor, rector, head of Dept of Faculty Therapy and Gastroenterology

mlivzan@yandex.ruhttps://orcid.org/0000-0001-9370-4768ГаусО. В.GausO. V.

Гаус Ольга Владимировна - кандидат медицинских наук, доцент кафедры факультетской терапии и гастроэнтерологии

Gaus Olga V. - PhD Med, associate professor at Dept of Faculty Therapy and Gastroenterology

gaus_olga@bk.ruФГБОУ ВО Омский государственный медицинский университет Минздрава РоссииРоссияOmsk State Medical UniversityRussian Federation202118122021035Практическая гастроэнтерология (3)4851Copyright © Федорин М.М., Ливзан М.А., Гаус О.В., 20212021Федорин М.М., Ливзан М.А., Гаус О.В.Fedorin М.М., Livzan M.A., Gaus O.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/2360

Увеличение доли населения, страдающей от избыточной массы тела или ожирения, сегодня принимает характер пандемии. В литературе стали появляться сообщения об имеющихся ассоциациях у лиц с нарушениями моторики толстой кишки и индексом массы тела выше 25 кг/м2. Настоящая публикация подготовлена с целью систематизации данных о возможных механизмах формирования нарушений моторики толстой кишки у лиц с избыточной массой тела и ожирением, в том числе путем изменения секреции и функции адипокинов. Поиск литературы проводился в системах Embase, PubMed и Google Scholar по ключевым словам «регуляция моторики толстой кишки», «адипокины», «желудочно-кишечные гормоны», «кишечная микробиота», «избыточная масса тела», «ожирение», «висцеральный жир».

The increasing proportion of the population suffering from overweight or obesity is now taking on the character of a pandemic. In the literature, there have begun to appear reports of associations in individuals with impaired colonic motility and a body mass index above 25 kg/m2. The present publication was prepared to systematize data on possible mechanisms of colonic motility disorders in overweight and obese individuals, including through changes in adipokine secretion and function. The literature search was performed in Embase, PubMed, and Google Scholar, using the key words ‘colon motility regulation’, ‘adipokines’, ‘gastrointestinal hormones’, ‘intestinal microbiota’, ‘overweight’, ‘obesity’, ‘visceral fat’.

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The authors declare that there are no conflicts of interest present.