medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2021-21-101-114medalphabet-2211Research ArticleЭНДОКРИНОЛОГИЯENDOCRINOLOGYПробиотики: настоящее и будущееProbiotics: present and futurehttps://orcid.org/0000-0003-3220-0333НикитинаЕ. А.NikitinaE. A.

Никитина Елена Александровна – кандидат медицинских наук, доцент кафедры диетологии и клинической нутрициологии.

Москва.

Elena A. Nikitina - PhD Med, assistant professor at Dept of Dietetics and Clinical Nutritiology.

Moscow.

nikitina-ea1@rudn.ruhttps://orcid.org/0000-0002-4689-3591ОрловаС. В.OrlovaS. V.

Орлова Светлана Владимировна – доктор медицинских наук, профессор, заведующая кафедрой диетологии и клинической нутрициологии.

Москва.

Svetlana V. Orlova - DM Sci, professor, head of Dept of Dietetics and Clinical Nutritiology.

Moscow.

rudn_nutr@mail.ruОрловаА. А.OrlovaA. A.

Орлова Анастасия Алексеевна - студентка медицинского института.

Москва.

Anastasia A. Orlova - student of Institute of Medicine.

Moscow.

1032202909@rudn.ruРоссийский университет дружбы народовРоссияPeoples' Friendship University of RussiaRussian Federation202125092021021Диетология и нутрициология (1)101114Copyright © Никитина Е.А., Орлова С.В., Орлова А.А., 20212021Никитина Е.А., Орлова С.В., Орлова А.А.Nikitina E.A., Orlova S.V., Orlova A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/2211

Адекватное взаимодействие между макроорганизмом и микробиотой лежит в основе правильного обмена веществ, роста и развития человека. Микробиом представляет собой совокупность микроорганизмов, тесно связанную с организмом человека и оказывающую всестороннее влияние на его здоровье и функционирование. Дополнительное введение пробиотиков может способствовать целенаправленной коррекции метаболических нарушений, воспалительной реакции, иммунного ответа и устойчивости к действию неблагоприятных факторов. Вместе с тем необходимо учитывать, что эффективность пробиотика зависит от выбранного штамма микроорганизма, формы, дозы и длительности применения. Данный обзор посвящен современным данным о роли пробиотиков в профилактике и комплексной терапии соматических заболевания.

Adequate interaction between macroorganism and microbiota underlies the correct metabolism, growth and development of а human. The microbiome is a collection of microorganisms that is closely related to the human body and has a comprehensive impact on its health and function. Additional administration of probiotics can assist targeted correction of metabolic disorders, inflammation, immune response, and resistance to adverse factors. At the same time, it must be considered that the effectiveness of a probiotics depend on the selected strain of the microorganism, form, dose and duration of use. This review is devoted to current data on the role of probiotics in the prevention and adjuvant therapy of somatic diseases.

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The authors declare that there are no conflicts of interest present.