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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2021-23-21-28</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2198</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СОВРЕМЕННАЯ ПОЛИКЛИНИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MODERN POLYCLINIC</subject></subj-group></article-categories><title-group><article-title>Неизвестное об известном: Lactobacillus plantarum. Вчера, сегодня, завтра</article-title><trans-title-group xml:lang="en"><trans-title>Unknown Known: Lactobacillus plantarum. Yesterday, Today, Tomorrow</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3220-0333</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елена Александровна Никитина, к. м. н., доцент кафедры диетологии и клинической нутрициологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Elena A. Nikitina, PhD, Assistant Professor of Department of Dietetics and Clinical Nutritiolog</p><p>Moscow</p></bio><email xlink:type="simple">mikitima-ea1@rudm.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4689-3591</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Светлана Владимировна Орлова, д. м. н., профессор, зав. кафедрой диетологии и клинической нутрициологии</p><p>Москва</p></bio><bio xml:lang="en"><p>Svetlana V. Orlova, DM Sci, Prof., Head of Department of Dietetics and Clinical Nutritiology</p><p>Moscow</p></bio><email xlink:type="simple">rudm_mutr@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4058-1706</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сергей Сергеевич Иванов, аспирант кафедры хирургической стоматологии и челюстно-лицевой хирургии Медицинского института</p><p>Москва</p></bio><bio xml:lang="en"><p>Sergey S. Ivanov, Postgraduate Student, Department of Surgical Dentistry and Maxillofacial Surgery of Institute of Medicine</p><p>Moscow</p></bio><email xlink:type="simple">1032133151@rudn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анастасия Алексеевна Орлова, студентка Медицинского института</p><p>Москва</p></bio><bio xml:lang="en"><p>Anastasia A. Orlova, Institute of Medicine student</p><p>Moscow</p></bio><email xlink:type="simple">1032202909@rudn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов» (РУДН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Рeoples’ Friendship University of Russia (RUDN University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>26</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>23</issue><issue-title>Современная поликлиника (3)</issue-title><fpage>21</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никитина Е.А., Орлова С.В., Иванов С.С., Орлова А.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Никитина Е.А., Орлова С.В., Иванов С.С., Орлова А.А.</copyright-holder><copyright-holder xml:lang="en">Nikitina E.A., Orlova S.V., Ivanov S.S., Orlova A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2198">https://www.med-alphabet.com/jour/article/view/2198</self-uri><abstract><p>Адекватное взаимодействие между макроорганизмом и микробиотой лежит в основе правильного обмена веществ и в целом здоровья человека. Пробиотики позволяют проводить целенаправленную коррекцию отдельных метаболических процессов, снижая риск развития заболеваний или повышая эффективность лекарственной терапии. Lactobacillus plantarum демонстрирует высокую эффективность в коррекции нарушений микробиоты, улучшении обмена веществ, регуляции воспаления и иммунитета. Проводится непрерывный поиск новых штаммов микроорганизмов, оказывающих иммунокоррегирующее и метаболическое действие.</p></abstract><trans-abstract xml:lang="en"><p>Adequate interaction between the macroorganism and the microbiota is the basis for proper metabolism and overall human health. Probiotics allow for targeted correction of individual metabolic processes, reducing the risk of developing diseases or increasing the effectiveness of drug therapy. Lactobacillus plantarum demonstrates high efficiency in correcting microbiota disorders, improving metabolism, regulating inflammation and immunity. A continuous search is carried out for new strains of microorganisms that have an immunocorregulating and metabolic effect.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>L. plantarum</kwd><kwd>пробиотики</kwd><kwd>микробиота</kwd><kwd>микробиоценоз</kwd><kwd>обмен веществ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>L. plantarum</kwd><kwd>probiotics</kwd><kwd>microbiota</kwd><kwd>microbiome</kwd><kwd>metabolism</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Публикация выполнена при поддержке Программы стратегического академического лидерства РУДН</funding-statement><funding-statement xml:lang="en">This publication was supported by Peoples’ Friendship University of Russia Strategic Academic Leadership Program</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">FAO/WHO Food and Agriculture Organization of the United Nations/World Health Organization Guidelines for the Evaluation of Probiotics in Food. 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