medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2021-21-22-26medalphabet-2185Research ArticleЭНДОКРИНОЛОГИЯENDOCRINOLOGYИммунонутриентные свойства лактоферрина и его защитная роль при новой коронавирусной инфекции COVID-19Immune properties of lactoferrin and its protective role in new coronavirus infection COVID-19https://orcid.org/0000-0002-4689-3591ОрловаС. В.OrlovaS. V.

Орлова Светлана Владимировна – доктор медицинских наук, профессор, заведующая кафедрой диетологии и клинической нутрициологии.

Москва.

Svetlana V. Orlova - DM Sci, prof., head of Dept of Dietetics and Clinical Nutritiology.

Moscow.

rudn_nutr@mail.ruhttps://orcid.org/0000-0003-3220-0333НикитинаЕ. А.NikitinaE. A.

Никитина Елена Александровна - кандидат медицинских наук, доцент кафедры диетологии и клинической нутрициологии.

Москва.

Elena A. Nikitina - PhD Med, assistant professor at Dept of Dietetics and Clinical Nutritiology.

Moscow.

nikitina-ea1@rudn.ruПрокопенкоЕ. В.ProkopenkoE. V.

Прокопенко Елена Валерьевна - врач-эндокринолог, диетолог, врач-методолог медицинского департамента.

Москва.

Elena V. Prokopenko - endocrinologist, nutritionist, methodologist of Medical Dept.

Moscow.

elvprokopenko@gmail.comВолковаЛ. Ю.VolkovaL. Yu.

Волкова Людмила Юрьевна – кандидат медицинских наук, старший преподаватель отдела организационно-методического управления и анализа качества медицинской помощи.

Москва.

Lyudmila Y. Volkova - PhD Med, senior lecturer at Dept of Organizational and Methodological Management and Analysis of Quality of Medical Care.

Moscow.

lvolkova2912@yandex.ruВодолазкаяА. Н.VodolazkayaA. N.

Водолазкая Ангелина Николаевна - врач диетолог-эндокринолог медицинского центра.

Москва.

Angelina N. Vodolazkaya - nutritionist-endocrinologis.

Moscow.

drvodolazkaya@gmail.comРоссийский университет дружбы народовРоссияPeoples' Friendship University of RussiaRussian FederationООО «МС Груп»РоссияMS GroupRussian FederationНациональный медицинский исследовательский центр терапии и профилактической медицины Минздрава РоссииРоссияNational Medical Research Centre for Therapy and Preventive MedicineRussian FederationООО «Эль-Клиник»РоссияEl-ClinicRussian Federation202125092021021Диетология и нутрициология (1)2226Copyright © Орлова С.В., Никитина Е.А., Прокопенко Е.В., Волкова Л.Ю., Водолазкая А.Н., 20212021Орлова С.В., Никитина Е.А., Прокопенко Е.В., Волкова Л.Ю., Водолазкая А.Н.Orlova S.V., Nikitina E.A., Prokopenko E.V., Volkova L.Y., Vodolazkaya A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/2185

Тысячи исследований были проведены для изучения нового коронавируса SARS-CoV-2, его инфекционных свойств, путей передачи и всего, что связано с клиническими проявлениями и тяжестью COVID-19, особенно потенциальными методами лечения. Лактоферрин -представитель семейства трансферринов, который синтезируется эпителиальными клетками внутренних желез млекопитающих и широко представлен в различных секреторных жидкостях, таких как молоко, слюна, слезы, секрет носовых желез. Лактоферрин является одним из компонентов врожденного гуморального иммунитета, регулирует функции иммунокомпетентных клеток и является белком острой фазы воспаления. Лактоферрин обладает выраженными антиоксидантным и противовоспалительным свойствами. В данном обзоре оценивается возможность использования лактоферрина в программах иммунокорригирующей диетотерапии при вирусных заболеваниях в том числе новой коронавирусной инфекции COVID-19.

Thousands of studies have been conducted to study the new SARS-CoV-2 coronavirus, its infectious properties, transmission routes and all associated with the clinical manifestations and severity of COVID-19, especially with potential treatments. Lactoferrin is a member of the transferrin family, which is synthesized by epithelial cells of mammalian internal glands and is widely present in various secretory fluids such as milk, saliva, tears, and nasal secretions. Lactoferrin is one of the components of the innate humoral immunity, regulates the functions of immunocompetent cells and is a acute phase protein. Lactoferrin has strong antioxidant and anti-inflammatory properties. This review assesses the possibility of using lactoferrin as a supplement in immunocorrective therapy programs for viral diseases, including the novel coronavirus infection COVID-19.

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The authors declare that there are no conflicts of interest present.