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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2021-26-43-46</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2180</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СОВРЕМЕННАЯ ГИНЕКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MODERN GYNECOLOGY</subject></subj-group></article-categories><title-group><article-title>Оптимизация лечебно-диагностических подходов и возможности прогнозирования степени риска нарушения микробиоты влагалища</article-title><trans-title-group xml:lang="en"><trans-title>Optimization of therapeutic and diagnostic approaches and possibility of predicting degree of risk of violation of vaginal microbiota</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8670-4516</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хурасева</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Khuraseva</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хурасева Анна Борисовна, доктор медицинских наук, доцент, профессор кафедры акушерства и гинекологии ИНО</p><p>Курск </p><p>SPIN: 5905–9909,</p><p>Researcher ID: ААВ‑6828–2020</p></bio><bio xml:lang="en"><p>Khuraseva Anna B., DM Sci, associate professor, professor at Dept of Obstetrics and Gynecology</p><p>Kursk</p><p>SPIN: 5905–9909,</p><p>Researcher ID: ААВ‑6828–2020</p></bio><email xlink:type="simple">anna_mail@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Реминная</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Reminnaya</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Реминная Татьяна Викторовна, заочный аспирант кафедры акушерства и гинекологии ИНО</p><p>Курск </p></bio><bio xml:lang="en"><p>Reminnaya Тatiana V., correspondence graduate student of Dept of Obstetrics and Gynecology</p><p>Kursk</p></bio><email xlink:type="simple">kololoka@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Курский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kursk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>24</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>26</issue><issue-title>Современная гинекология (2)</issue-title><fpage>43</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хурасева А.Б., Реминная Т.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Хурасева А.Б., Реминная Т.В.</copyright-holder><copyright-holder xml:lang="en">Khuraseva A.B., Reminnaya T.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2180">https://www.med-alphabet.com/jour/article/view/2180</self-uri><abstract><sec><title>Цель</title><p>Цель. Оптимизация эффективности диагностики и прогнозирования степени риска нарушения микробиоты влагалища.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Были обследованы 572 пациентки с жалобами на обильные выделения из половых путей и (или) неприятный запах. Все женщины наблюдались в соответствии с анамнестическими, клиническими, лабораторными критериями.</p></sec><sec><title>Результаты и выводы</title><p>Результаты и выводы. При обследовании пациенток полученные результаты анамнестических, клинических и лабораторных признаков оценивались по балльной системе с учетом их информативности и вероятности влияния на микробиом влагалища. На основании анализа данных был предложен способ прогнозирования степени риска нарушения микробиоты влагалища. Способ позволяет осуществлять персонифицированный лечебно-диагностический подход и позволяет как можно раньше прогнозировать риск нарушения микробиоты влагалища.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Goal</title><p>Goal. Optimization of the effectiveness of diagnosis and prediction of the degree of risk of violation of the vaginal microbiota.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 572 patients were examined with complaints of copious discharge from the genital tract and/or an unpleasant smell. All women were observed in accordance with anamnestic, clinical, and laboratory criteria.</p></sec><sec><title>Results and conclusions</title><p>Results and conclusions. When examining patients, the results of anamnestic, clinical and laboratory signs were evaluated according to a point system, taking into account their informative value and the probability of influencing the vaginal microbiome. Based on the data analysis, a method for predicting the degree of risk of violation of the vaginal microbiota was proposed. The method allows for a personalized therapeutic and diagnostic approach and allows predicting the risk of violation of the vaginal microbiota as early as possible.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>дисбиоз</kwd><kwd>микробиота</kwd><kwd>вагинальная среда</kwd><kwd>оценка микробиоценоза</kwd></kwd-group><kwd-group xml:lang="en"><kwd>dysbiosis</kwd><kwd>microbiota</kwd><kwd>vaginal environment</kwd><kwd>assessment of microbiocenosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бондаренко К. Р., Доброхотова Ю. Э., Новик М.Ю. Возможности профилактики поздних акушерских осложнений путем коррекции эндогенной микробиоты. Медицинский алфавит. 2017. Т3. 23 (320). 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