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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2021-26-37-42</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2179</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СОВРЕМЕННАЯ ГИНЕКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MODERN GYNECOLOGY</subject></subj-group></article-categories><title-group><article-title>Применение нифуратела в лечении цистита у женщин</article-title><trans-title-group xml:lang="en"><trans-title>Аpplication of nifuratel in treatment of cystitis in women</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельник</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnik</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мельник Екатерина Григорьевна, кандидат медицинских наук, доцент кафедры акушерства, гинекологии с курсом дерматовенерологии</p><p>Краснодар </p></bio><bio xml:lang="en"><p>Melnik Ekaterina G., PhD Med, associate professor at Dept of Obstetrics, Gynecology with a Course of Dermatovenerology</p><p>Krasnodar</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НОЧУ ВО «Кубанский медицинский институт»,</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuban Medical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>24</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>26</issue><issue-title>Современная гинекология (2)</issue-title><fpage>37</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мельник Е.Г., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Мельник Е.Г.</copyright-holder><copyright-holder xml:lang="en">Melnik E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2179">https://www.med-alphabet.com/jour/article/view/2179</self-uri><abstract><p>Цистит – самая распространенная патология мочевыводящих путей у женщин как у нас в стране, так и за рубежом. На высокую частоту встречаемости данного заболевания у женщин в популяции оказывают влияние анатомические, физиологические особенности женского организма, нарушения личной и половой гигиены, отягощенный акушерско-гинекологическим анамнез (ОАГА) и др. В действующих отечественных и зарубежных рекомендациях по диагностике и лечению цистита у женщин отмечено, что в подавляющем большинстве случаев (до 80% случаев) возбудителем цистита является Escherichia coli, чувствительная к препаратам нитрофуранового ряда.</p><sec><title>Цель работы</title><p>Цель работы. На клинических примерах продемонстрировать эффективность использования нифуратела (Нифурател-СЗ, «Северная звезда», Россия) у женщин с циститом различных возрастных групп. В первом клиническом примере показана высокая результативность применения нитрофурана у женщины активного репродуктивного возраста с ОАГА, во втором – у подростка с острым воспалительным процессом, в третьем – у пациентки постменопаузального периода с сопутствующей полиорганной патологией.</p></sec><sec><title>Заключение</title><p>Заключение. Нифурател (Нифурател-СЗ, «Северная звезда», Россия) зарекомендовал себя высокоэффективным и безопасным лекарственным средством с широким диапазоном антибактериального действия у пациенток с циститом разных возрастных групп.</p></sec></abstract><trans-abstract xml:lang="en"><p>Cystitis is the most common pathology of the urinary tract in women both in our country and abroad. The high incidence of this disease in women in the population is influenced by anatomical, physiological features of the female body, violations of personal and sexual hygiene, burdened with an obstetric and gynecological (OAG) history, etc. In the current domestic and foreign recommendations for the diagnosis and treatment of cystitis in women, it is noted that in the vast majority of cases (up to 80% cases), the causative agent of cystitis is Escherichia coli, sensitive to nitrоfuran drugs.</p><sec><title>The purpose of the work</title><p>The purpose of the work. To demonstrate the effectiveness of the use of nifuratel (Nifuratel-SZ, Northern Star Co., Russia) in women with cystitis of various age groups using clinical examples. In the first clinical example, the high effectiveness of the use of nitrоfuran was shown in a woman of active reproductive age with OAG, in the second, in a teenager with an acute inflammatory process, in the 3rd-in a postmenopausal patient with concomitant multiple organ pathology.</p></sec><sec><title>Conclusion</title><p>Conclusion. Nifuratel (Nifuratel-SZ, Northern Star Co., Russia) has proven to be a highly effective and safe drug with a wide range of antibacterial effects in patients with cystitis of different age groups.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>цистит</kwd><kwd>женщины</kwd><kwd>нифурател</kwd><kwd>эффективность</kwd><kwd>безопасность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cystitis</kwd><kwd>women</kwd><kwd>nifuratel</kwd><kwd>efficacy</kwd><kwd>safety</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шипицына Е.В., Хуснутдинова Т.А., Савичева А.М., Айвазян Т.А. Инфекции мочевыводящих путей в акушерстве и гинекологии. Журнал акушерства и женских болезней. 2015; LXIV (выпуск 6): 91–104.</mixed-citation><mixed-citation xml:lang="en">Shipitsyna E.V., Khusnutdinova T.A., Savicheva A.M., Ayvazyan T.A. Urinary tract infections in obstetrics and gynecology. 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