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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2021-9-97-100</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2051</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕВМАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RHEUMATOLOGY</subject></subj-group></article-categories><title-group><article-title>Эффективность микронидлинга аутологичной  плазмы с клетками у пациентов с атрофическими  рубцами постакне</article-title><trans-title-group xml:lang="en"><trans-title>Efficacy of autologous plasma microneedling with cells in patients with  post-acne atrophic scars</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0850-3238</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Талыбова</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Talybova</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Талыбова Алия Пашаевна,к. м. н., врач-дерматовенеролог, врач-косметолог</p></bio><bio xml:lang="en"><p>Talybova Aliya P., PhD Med, dermatovenerologist, cosmetologist</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3437-5233</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грязева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gryazeva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Грязева Наталья Владимирона, к. м. н., доцент кафедры дерматовенерологии и косметологии.</p><p>SPIN-код: 1309–4668</p></bio><bio xml:lang="en"><p>Gryazeva Natalia V.,PhD Med, associate prof. at Department of Dermatovenerology and Cosmetology</p><p>SPIN code: 1309–4668</p></bio><email xlink:type="simple">tynrik@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy of the Presidential Administration of the Russian Federation, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>АО «Институт пластической хирургии и косметологии», Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Plastic Surgery and Cosmetology, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>25</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>9</issue><issue-title>Дерматология (1)</issue-title><fpage>97</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Талыбова А.П., Грязева Н.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Талыбова А.П., Грязева Н.В.</copyright-holder><copyright-holder xml:lang="en">Talybova A.P., Gryazeva N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2051">https://www.med-alphabet.com/jour/article/view/2051</self-uri><abstract><p>Цель исследования:изучить эффективность микронидлинга с аутологичной плазмой с клетками у пациентов с различными фенотипами атрофических рубцов постакне. В 1А группу (n = 32) вошли пациенты с атрофическими рубцами постакне: ice pick – 12 пациентов; boxcar – 11; rolling – 9 пациентов. Группу 1В составили 34 пациента с рубцами ice pick – 12; boxcar – 12; rolling – 10 пациентов. В группе 1А пациентам проводилась процедура микронидлинга. В группе 1В микронидлинг проводился с аутологичной плазмой с клетками. Для оценки эффективности методов терапии в работе использовалась модифицированная для рубцов постакне шкала IGA (Investigators Global Assessment), адаптированная для рубцов постакне, – Assessment of the Psychological and Social Effects of Acne (APSEA). Специальные методы включали ультразвуковое исследование с помощью ультразвукового сканера IU 22. Конечный результат при различных фенотипах рубцов постакне показал преимущества разработанного комплекса при АР boxcar и rolling и несколько более низкую при ice pick. Рекомендуемый курс терапии составляет три процедуры, проводимые раз в 4 недели.</p></abstract><trans-abstract xml:lang="en"><p>Objective: to studythe effectiveness of autologous plasma-cell microneedling in patients with different phenotypes of post-acne atrophic scars. Group 1A (n = 32) included patients with post – acne atrophic scars: ice pick – 12 patients; boxcar – 11; rolling – 9 patients. Group 1B consisted of 34 patients with scars ice pick – 12; boxcar – 12; rolling – 10 patients. In group 1A, patients underwent a microneedling procedure. In group 1B, microneedling was performed with autologous plasma with cells. To evaluate the effectiveness of the therapy methods, we used the IGA (Investigators Global Assessment) scale modified for post-acne scars, adapted for post-acne scars by the Assessment of the Psychological and Social Effects of Acne (APSEA). Special methods included ultrasound examination using an ultrasound scanner IU 22. The end result for different post-acne scar phenotypes showed the advantages of the developed complex for boxcar and rolling AR and slightly lower for ice pick. The recommended course of therapy is three procedures performed once in 4 weeks.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>атрофические рубцы постакне</kwd><kwd>микронидлинг</kwd><kwd>аутологичная плазма с клетками</kwd></kwd-group><kwd-group xml:lang="en"><kwd>post-acne atrophic scars</kwd><kwd>microneedling</kwd><kwd>autologous plasma with cells.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Акне и розацеа. Под редакцией Кругловой Л. С. 2021. 207 с.</mixed-citation><mixed-citation xml:lang="en">Acne and rosacea. Edited by Kruglova L. S. 2021. 207 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Tremblay JF. Plasma skin regeneration (PSR) in the treatment of acne scars. J Am Acad Dermatol. 2007; 56 (Suppl 2): A7–A8.</mixed-citation><mixed-citation xml:lang="en">Tremblay JF. Plasma skin regeneration (PSR) in the treatment of acne scars. J Am Acad Dermatol. 2007; 56 (Suppl 2): A7–A8.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Потекаев Н. Н., Круглова Л. С. Лазер в дерматологии и косметологии. Москва. МДВ. 2018. 280 с.</mixed-citation><mixed-citation xml:lang="en">Potekaev N. N., Kruglova L. S. Laser in dermatology and cosmetology. Moscow. MDV. 2018. 280 p.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Singh A, Yadav S. Microneedling: advances and widening horizons. Indian Dermatol Online J. 2016; 7: 244–254.</mixed-citation><mixed-citation xml:lang="en">Singh A, Yadav S. Microneedling: advances and widening horizons. Indian Dermatol Online J. 2016; 7: 244–254.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">El-Domyati M, Barakat M, Awad S, et al. Microneedling therapy for atrophic acne scars: an objective evaluation. J Clin Aesthet Dermatol. 2015; 8: 36–42.</mixed-citation><mixed-citation xml:lang="en">El-Domyati M, Barakat M, Awad S, et al. Microneedling therapy for atrophic acne scars: an objective evaluation. J Clin Aesthet Dermatol. 2015; 8: 36–42.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Fabbrocini G, De Vita V, Pastore F. The use of skin needling for eutectic mixture of local anesthetics delivery. Dermat Ther. 2011; 2: 188–192.</mixed-citation><mixed-citation xml:lang="en">Fabbrocini G, De Vita V, Pastore F. The use of skin needling for eutectic mixture of local anesthetics delivery. Dermat Ther. 2011; 2: 188–192.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Marx RE. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg. 2004; 62: 489–496.</mixed-citation><mixed-citation xml:lang="en">Marx RE. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg. 2004; 62: 489–496.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med. 2006; 32: 289–299</mixed-citation><mixed-citation xml:lang="en">Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med. 2006; 32: 289–299</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
