medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2021-9-94-96medalphabet-2050Research ArticleРЕВМАТОЛОГИЯRHEUMATOLOGYФормирование гранулем после введения дермального наполнителя на основе поликапролактона (клинический случай)Granuloma formation after injection of polycaprolactone dermal filler (case report)https://orcid.org/0000-0002-8813-9132ИконниковаЕ. В.IkonnikovaE. V.

Иконникова Евгения Владимировна,доцент кафедры дерматовенерологии и косметологии

Ikonnikova Evgeniya V.,associate prof. at Dermatovenereology and Cosmetology Dept

evikonnikova@bk.ruhttps://orcid.org/0000-0002-5044-5265КругловаЛ. С.KruglovaL. S.

Круглова Лариса Сергеевна, д. м. н., проф., зав. кафедрой дерматовенерологии и косметологии, проректор по учебной работе

Kruglova Larisa S.,DM Sci, prof., head of Dept of Dermatovenereology and Cosmetology. vice-rector for Academic Affairs

kruglovals@mail.ruФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента России, МоскваРоссияCentral State Medical Academy of the Administrative Department of the President of Russia, MoscowRussian Federation20212506202109Дерматология (1)9496Copyright © Иконникова Е.В., Круглова Л.С., 20212021Иконникова Е.В., Круглова Л.С.Ikonnikova E.V., Kruglova L.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/2050

Представлен случай клинического наблюдения пациента с гранулематозной реакцией, развившейся в области обеих носослезных борозд после введения филлера на основе поликапролактона (PCL). PCL применяется в косметологии в качестве наполнителя и стимулятора синтеза коллагена. Он является биосовместимым и биоразлагаемым полимером, имеет подтвержденный профиль безопасности. Однако, как и при введении других видов филлеров, в ряде случаев он способен вызвать гранулематозную реакцию разной степени выраженности. Клиническое наблюдение этого случая представляет интерес для практикующих дерматологов, косметологов и пластических хирургов.

A case of clinical observation of a patient with a granulomatous reaction developing in the region of both nasolacrimal grooves after the injection of a filler based on polycaprolactone (PCL) is presented. PCL is used in cosmetology as a filler and collagen synthesis stimulator. It is a biocompatible and biodegradable polymer with a proven safety profile. However, as with the introduction of other types of fillers, in some cases it can cause a granulomatous reaction of varying severity. The clinical observation of this case is of interest to practicing dermatologists, cosmetologists and plastic surgeons.

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The authors declare that there are no conflicts of interest present.