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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2021-9-59-62</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2041</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОСМЕТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>КОСМЕТОЛОГИЯ</subject></subj-group></article-categories><title-group><article-title>Эффективность микронидлинга в коррекции  инволютивных изменений кожи</article-title><trans-title-group xml:lang="en"><trans-title>Effectiveness of microneedling in correction of involutive skin changes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1898-678X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авагумян</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Avagumyan</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Авагумян Мария Армаисовна,врач-дерматовенеролог, косметолог</p></bio><bio xml:lang="en"><p>Avagumyan Maria A. dermatovenerologist, cosmetologist</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1681-0273</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гресь</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gres</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гресь София Николаевна, врач-дерматовенеролог, косметолог, ассистент кафедры общественного здоровья, здравоохранения и гигиены</p></bio><bio xml:lang="en"><p>Gres Sofia N., dermatovenerologist, cosmetologist, assistant at Dept of Public Health, Health and Hygiene</p></bio><email xlink:type="simple">89104679102@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинский научно-образовательный центр (университетская клиника) ФГБОУ ВО «Московский государственный &#13;
университет имени М. В. Ломоносова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Research and Educational Centre (University Clinic) of Moscow State University n. a. M. V. Lomonosov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>25</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>9</issue><issue-title>Дерматология (1)</issue-title><fpage>59</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Авагумян М.А., Гресь С.Н., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Авагумян М.А., Гресь С.Н.</copyright-holder><copyright-holder xml:lang="en">Avagumyan M.A., Gres S.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2041">https://www.med-alphabet.com/jour/article/view/2041</self-uri><abstract><p>В клинической практике, как правило, у пациентов с инволютивными изменениями отмечается фотоповреждение на фоне физиологического старения, что должно учитываться при выборе метода коррекции. Перспективным можно считать микронидлинг, в том числе с применением PRP и гиалуроновой кислоты.</p><sec><title>Материал и методы</title><p>Материал и методы. Под наблюдением находилось 50 пациентов, которые были разделены на три группы: первая группа – 18 пациентов получали микронидлинг и PRP; вторая группа – 17 человек применяли микронидлинг гиалуроновой кислоты, третья группа – 15 пациентов получали микронидлинг. Проводили четыре процедуры с интервалом 4 недели.</p></sec><sec><title>Результаты исследования</title><p>Результаты исследования.Совокупная оценка регресса клинической симптоматики с учетом индекса дерматологического статуса показала преимущества микронидлинга PRP: в среднем по группе индекс снизился на 86 %. Во второй группе в среднем по группе индекс снизился на 56 %, в третьей группе – 41 %.</p></sec><sec><title>Выводы</title><p>Выводы. Микронидлинг – эффективная безопасная методика коррекции инволютивных изменений кожи лица, в том числе при сочетании с признаками фотостарения. Для повышения эффективности микронидлинга рекомендуется непосредственно после процедуры применение аутологичной плазмы с клетками в методике накожного нанесения.</p></sec></abstract><trans-abstract xml:lang="en"><p>In clinical practice, as a rule, patients with involutive changesas well havea photodamage, it should be considered when choosing a method of correction. Microneedling, including the use of PRP and hyaluronic acid, arevery promising methods.</p><sec><title>Material and methods</title><p>Material and methods. There were 50 patients under observation, who were divided into three groups: 1st group – 18 patients received microneedling and PRP, 2nd group – 17 people used microneedling of hyaluronic acid, 3rd group – 15 patients received microneedling. Four procedures were performed with an interval of 4 weeks.</p></sec><sec><title>Results</title><p>Results. According to dermatological status index, PRP microneedlingshowed the effectiveness, the index decreased by 86 % in the group. In group 2, the average index for the group decreased by 56 %, in group 3–41 %.</p></sec><sec><title>Conclusions</title><p>Conclusions.Microneedling is an effective safe method for correcting involutive changes in the skin of the face, combined with signs of photoaging. To increase the effectiveness of microneedling, it is recommended to use autologous plasma with cells directly after the procedure applicationinto the form or the film.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инволютивные изменения кожи</kwd><kwd>фотостарение</kwd><kwd>микронидлинг</kwd><kwd>PRP</kwd><kwd>гиалуроновая кислота</kwd></kwd-group><kwd-group xml:lang="en"><kwd>involutive skin changes</kwd><kwd>photoaging</kwd><kwd>microneedling</kwd><kwd>PRP</kwd><kwd>hyaluronic acid</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Пaccватер Р. Свободнopaдикальная тeopия стapeния. Кocметика и мeдицинa. 1998. № 2. С. 7–13.</mixed-citation><mixed-citation xml:lang="en">Pasvater R. Free radical theory of aging. Cosmetics and medicine. 1998. No. 2. 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