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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2021-9-12-15</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-2029</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group></article-categories><title-group><article-title>Оценка качества жизни пациентов с акне тяжелой степени</article-title><trans-title-group xml:lang="en"><trans-title>Assessment of quality of life in patients with severe acne</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3437-5233</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Грязева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gryazeva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Грязева Наталья Владимировна, к. м. н., доцент кафедрыдерматовенерологии и косметологии</p></bio><bio xml:lang="en"><p> Gryazeva Natalia V., PhD Med, associate prof. at Dept of Dermatovenerology and Cosmetology</p></bio><email xlink:type="simple">tynrik@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4672-697X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тамразова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tamrazova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Тамразова Анаит Вардановна, ординатор кафедры дерматовенерологии и косметологии</p></bio><bio xml:lang="en"><p> Tamrazova Anahit V., resident of Dept of Dermatovenerology and Cosmetology</p></bio><email xlink:type="simple">anaittamrazova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента России<country>Россия</country></aff><aff xml:lang="en">Central State Medical Academy of the Administrative Department of the President of Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>23</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>9</issue><issue-title>Дерматология (1)</issue-title><fpage>11</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Грязева Н.В., Тамразова А.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Грязева Н.В., Тамразова А.В.</copyright-holder><copyright-holder xml:lang="en">Gryazeva N.V., Tamrazova A.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/2029">https://www.med-alphabet.com/jour/article/view/2029</self-uri><abstract><p>Вульгарные угри являются распространенным заболеванием, поражающим до 85 % подростков. Локализация дерматоза в косметически значимых зонах, длительность течения и формирование симптомов постакне оказывают высокую психоэмоциональную нагрузку и негативно сказываются на качестве жизни. Ввиду того что акне поражает самую уязвимую и зависимую от социальной оценки возрастную группу, крайне важно не пропустить психологические отклонения, такие как тревога, депрессия и суицидальные мысли. В данном обзоре представлены виды диагностических шкал для оценки качества жизни пациентов с акне, патогенез и факторы риска образования рубцов – главного фактора, влияющего на самооценку пациентов с вульгарными угрями, а также предложены новые способы комбинированной терапии с использование кортикостероидов и изотретиноина при лечении тяжелых форм.</p></abstract><trans-abstract xml:lang="en"><p>Acne vulgaris is a common disease affecting up to 85 % of adolescents. Localization of dermatosis in cosmetically signifiant areas, the duration of the therapy and the formation of post-acne symptoms have a high psycho-emotional load and negatively affect the quality of life. Due to the fact that acne affects the most vulnerable and socially sensitive age group, it is imperative not to overlook psychological abnormalities such as anxiety, depression and suicidal thoughts. This review presents the types of diagnostic scales for assessing the quality of life of patients with acne, pathogenesis and risk factors for scar formation – the main factor affecting the self-esteem of patients with acne vulgaris, and also proposed new methods of combination therapy with the use of corticosteroids and isotretinoin in the treatment of severe forms.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>акне</kwd><kwd>тяжелые формы акне</kwd><kwd>качество жизни</kwd><kwd>ДИКЖ</kwd><kwd>рубцы</kwd><kwd>изотретиноин</kwd><kwd>кортикостероиды</kwd><kwd>преднизолон</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acne</kwd><kwd>severe acne</kwd><kwd>quality of life</kwd><kwd>DLQI</kwd><kwd>acne scars</kwd><kwd>isotretinoin</kwd><kwd>corticosteroids</kwd><kwd>prednisolone</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Strauss JS, Krowchuk DP, Leyden JJ, Lucky AW, Shalita AR, Siegfried EC et al.; American Academy of Dermatology / American Academy of Dermatology Association. 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