Материалы и методы

medalphabet

Медицинский алфавит

Medical alphabet

2078-56312949-2807

ООО «Альфмед»

10.33667/2078-5631-2021-2-24-37

medalphabet-1915

Research Article

Статьи

Заболевание пародонта – местная антисептическая терапия: проблема эффективности. Обзор литературы

Periodonal desiease – local antiseptic therapy: problem of efficiency. Literature review

https://orcid.org/0000-0002-7257-5503

Хабадзе

З. С.

Khabadze

Z. S.

к.м.н., доцент кафедры терапевтической стоматологии,

Москваморд

Candidate of Medical Sciences, Associate Professor of the Department of Therapeutic Dentistry,

Moscow

https://orcid.org/0000-0003-1926-7162

Генералова

Ю. А.

Generalova

Y. A.

студент,

Москва

student,

Moscow

https://orcid.org/0000-0003-0168-8129

Шубаева

В. С.

Shubaeva

V. S.

студент,

Москва

student,

Moscow

https://orcid.org/0000-0002-4471-2128

Абдулкеримова

С. М.

Abdulkerimova

S. M.

врач-стоматолог,

Москва

dentist,

Moscow

https://orcid.org/0000-0002-0179-4717

Бакаев

Ю. А.

Bakaev

Y. A.

врач-стоматолог,

Москва

dentist,

Moscow

https://orcid.org/0000-0002-9878-7045

Морданов

О. С.

Mordanov

O. S.

врач-стоматолог,

Москва

dentist,

Moscow

Mordanov19@gmail.com

Российский университет дружбы народовРоссияRussian Peoples’ Friendship UniversityRussian Federation

Частная стоматологическая практикаРоссияPrivate dental practiceRussian Federation

2021

25032021

Стоматология (1)

2437

2021

Хабадзе З.С., Генералова Ю.А., Шубаева В.С., Абдулкеримова С.М., Бакаев Ю.А., Морданов О.С.

Khabadze Z.S., Generalova Y.A., Shubaeva V.S., Abdulkerimova S.M., Bakaev Y.A., Mordanov O.S.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.med-alphabet.com/jour/article/view/1915

Целью данной обзорной статьи является анализ актуальных данных относительно применения антисептических средств в терапии пародонтита, развития резистентности пародонтопатогенов к антисептическим агентам на примере хлоргексидина, цетилпиридиния хлорида и гексетидина. Пародонтопатогены являются неотъемлемой частью комменсальной микрофлоры полости рта, но в определенных условиях и под влиянием этиологических факторов их количество начинает прогрессивно расти, что повышает риск инициации заболеваний пародонта посредством возникновения агрессивной биопленки на зубах.

Материалы и методы

Материалы и методы. Было произведено изучение публикаций в электронных базах данных PubMed и Google Scholar в ходе систематического обзора литературы. Включены статьи, содержание которых касается данных по антисептическим агентам, а именно – хлоргексидину, цетилпиридиния хлориду и гексетидину, а также их влияния на пародонтопатогены и возможности развития у них резистентности относительно данных антисептиков.

Результаты

Результаты. В ходе обзора было рассмотрено 127 статей. После анализа литературы по критериям включения итоговое количество составило 94 публикации.

Выводы

Выводы. Исходя из проанализированных данных, мы пришли к выводу, что антисептическая обработка полости рта и зон поражения при пародонтите является неотъемлемой частью терапии данного воспалительного заболевания как дополнение к протоколу механической обработки. Особую активность в отношении пародонтопатогенов показал хлоргексидин в местных формах доставки.

The purpose of this review article is to analyze the current data on the use of antiseptics in the treatment of periodontitis, development of resistance of periodontopathogens to antiseptic agents using the example of chlorhexidine, cetylpyridinium chloride and hexetidine. Periodontal pathogens are an integral part of the commensal microflora of the oral cavity, but under certain conditions and under the influence of etiological factors, their number begins to progressively grow, which increases the risk of initiation of periodontal diseases through the formation of aggressive biofilm on the teeth.

Materials and methods

Materials and methods. Тhe study of publications was produced in the electronic databases such as PubMed and Google Scholar in the course of a systematic review of the literature. Included articles contain information about antiseptic agents which are chlorhexidine, cetylpyridinium chloride and hexetidine, as well as their effect on periodontopathogens and the possibility of developing resistance in them against these antiseptics.

Results

Results. 127 articles were viewed during the review. After analyzing the literature for inclusion criteria, the total number of publications has become 94.

Conclusions

Conclusions. Аccording to the analyzed data, we have found that antiseptic treatment of the oral cavity and lesions in periodontitis is an integral part of the treatment of this inflammatory disease, as an addition to the mechanical treatment protocol. Chlorhexidine in local forms of delivery has shown particular activity against periodontopathogens.

пародонтитрезистентность пародонтопатогеновхлоргексидинцетилпиридиния хлоридгексетидин

marginal periodontitisresistance of periodontal pathogenschlorhexidinecetylpyridinium chloridehexetidine

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The authors declare that there are no conflicts of interest present.