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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2020-38-21-24</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-1886</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Возможности магнитно-резонансной томографии в уточнении степени злокачественности хондросаркомы костей</article-title><trans-title-group xml:lang="en"><trans-title>Role of magnetic resonance imaging in prediction of chondrosarcoma of bone grade</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федорова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., н.с.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кочергина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kochergina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., проф., в.н.с.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блудов</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Bludov</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., н.с.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Булычева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Boulycheva</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., врач-патоморфолог</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сушенцов</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sushentsov</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., зав. отделением онкоортопедии</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Спирина</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Spirina</surname><given-names>O. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-рентгенолог</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щипахина</surname><given-names>Я. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchipakhina</surname><given-names>Ya. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., н.с.</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Неред</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nered</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-рентгенолог</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Centre of Oncology n.a. N.N. Blokhin</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина» Минздрава России; ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Centre of Oncology n.a. N.N. Blokhin; Russian Medical Academy of Continuous Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Сеть медицинских центров ООО «Медскан»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medscan Co.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>22</day><month>01</month><year>2021</year></pub-date><volume>0</volume><issue>38</issue><issue-title>Диагностика и онкотерапия (4)</issue-title><fpage>21</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Федорова А.В., Кочергина Н.В., Блудов А.Б., Булычева И.В., Сушенцов Е.А., Спирина О.Г., Щипахина Я.А., Неред А.С., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Федорова А.В., Кочергина Н.В., Блудов А.Б., Булычева И.В., Сушенцов Е.А., Спирина О.Г., Щипахина Я.А., Неред А.С.</copyright-holder><copyright-holder xml:lang="en">Fedorova A.V., Kochergina N.V., Bludov A.B., Boulycheva I.V., Sushentsov E.A., Spirina O.G., Shchipakhina Y.A., Nered A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/1886">https://www.med-alphabet.com/jour/article/view/1886</self-uri><abstract><p>Цель. Определить диагностическую ценность стандартной МРТ в уточнении степени злокачественности хондросарком костей на предоперационном этапе. Материалы и методы. Были проанализированы данные МРТ без внутривенного контрастирования 70 пациентов с хондросаркомами (по 35 пациентов в группах низко- и высокозлокачественных хондросарком). Вычислялись весовые коэффициенты информативности отдельно для «обучающей» и «экзаменационной» выборок, на основе которых создавалось «решающее правило» для разграничения групп низко- и высокозлокачественных хонодросарком. Результаты. Чувствительность метода составила 87,0 %, специфичность – 95,6 %, точность – 91,3 %. Заключение. Магнитно-резонансная томография является высокоинформативным методом предсказания степени злокачественности хондросарком на предоперационном этапе ведения пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Purpose. Determining the diagnostic value of magnetic resonance imaging in the accurate definition of chondrosarcoma of bone grade at the pre-surgery examination. Material and methods. We analyzed examination data (magnetic resonance imaging with no contrast enhancement) of 70 patients with chondrosarcoma (35 patients with low-grade chondrosarcoma and 35 patients with high grade chondrosarcoma). Informative weighted coefficients were determined separately for ‘learning’ and ‘examination’ samples. On the basis of weighted coefficients, the decisive rule was created for differentiation between low-grade and high-grade chondrosarcoma. Results. The sensitivity of the method was 87.0%, specificity was 95.6%, total correct classification was 91.03%. Conclusion. Magnetic resonance imaging is a highly informative method for prediction of chondrosarcoma grade at the pre-surgery examination.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>опухоли костей</kwd><kwd>хондросаркома</kwd><kwd>магнитно-резонансная томография</kwd><kwd>степень злокачественности</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bone tumor</kwd><kwd>chondrosarcoma</kwd><kwd>magnetic resonance imaging</kwd><kwd>grade</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Douis H. The imaging of cartilaginous bone tumours. II. Chondrosarcoma. H. Douis, A. Saifuddin. Skeletal Radiol. 2013. Vol. 42 (5). P. 611–626.</mixed-citation><mixed-citation xml:lang="en">Douis H. The imaging of cartilaginous bone tumours. II. Chondrosarcoma. H. Douis, A. Saifuddin. Skeletal Radiol. 2013. Vol. 42 (5). 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