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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-186</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Антидепрессанты в профилактике мигрени</article-title><trans-title-group xml:lang="en"><trans-title>Antidepressants in prevention of migraine</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаров</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarov</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Филатова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Filatova</surname><given-names>E. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет имени И. М. Сеченова (Сеченовский университет)» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Moscow State Medical University n.a. I. M. Sechenov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>16</day><month>05</month><year>2017</year></pub-date><volume>2</volume><issue>15</issue><issue-title>Неврология и психиатрия</issue-title><fpage>33</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Макаров С.А., Филатова Е.Г., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Макаров С.А., Филатова Е.Г.</copyright-holder><copyright-holder xml:lang="en">Makarov S.A., Filatova E.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/186">https://www.med-alphabet.com/jour/article/view/186</self-uri><abstract><p>В обзоре представлена современная информация о хронической мигрени и её лечении при помощи антидепрессантов. Обсуждаются механизмы анальгетического действия антидепрессантов. Подробно излагаются материалы об эффективности отдельных представителей антидепрессантов разных групп. Рассматриваются национальные рекомендации по лечению хронической мигрени в разных странах (Соединенных Штатах Америки, Европе, России).</p></abstract><trans-abstract xml:lang="en"><p>The review presents current information on chronic migraine and its treatment with antidepressants. The mechanisms of analgesic action of antidepressants are discussed. Details of the effectiveness of individual representatives of antidepressants of different groups. National recommendations on chronic migraine treatment in different countries (United States of America, Europe, Russia) are considered</p></trans-abstract><kwd-group xml:lang="ru"><kwd>антидепрессанты</kwd><kwd>хроническая мигрень</kwd></kwd-group><kwd-group xml:lang="en"><kwd>antidepressants</kwd><kwd>chronic migraine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Buse DC, Manack AN, Fanning KM, et al. Chronic migraine prevalence, disability, and sociodemographic factors: Results from the American Migraine Prevalence and Prevention Study. Headache 2012; 52: 1456-1470.</mixed-citation><mixed-citation xml:lang="en">Buse DC, Manack AN, Fanning KM, et al. Chronic migraine prevalence, disability, and sociodemographic factors: Results from the American Migraine Prevalence and Prevention Study. 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