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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2020-24-91-93</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-1796</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTURE</subject></subj-group></article-categories><title-group><article-title>Микроциркуляторные и вегетативные изменения у детей с разными фенотипами аллергического ринита</article-title><trans-title-group xml:lang="en"><trans-title>Microcirculatory and vegetative changes in children with different phenotypes of allergic rhinitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Татаурщикова</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tataurschikova</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., проф., зав. кафедрой медико-социальной адаптологии ФНМО,</p><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бережанский</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Berezhansky</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-педиатр,</p><p>г. Одинцово</p></bio><bio xml:lang="en"><p>Odintsovo, Moscow Region</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинский институт ФГАОУ ВО «Российский университет дружбы народов»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ МО «Одинцовская областная больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Odintsovo Regional Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2020</year></pub-date><volume>0</volume><issue>24</issue><issue-title>Дерматология (2)</issue-title><fpage>91</fpage><lpage>93</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Татаурщикова Н.С., Бережанский П.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Татаурщикова Н.С., Бережанский П.В.</copyright-holder><copyright-holder xml:lang="en">Tataurschikova N.S., Berezhansky P.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/1796">https://www.med-alphabet.com/jour/article/view/1796</self-uri><abstract><p>Микроциркуляторные и вегетососудистые механизмы имеют важное патогенетическое значение в развитии аллергического воспаления.</p><p>Цель нашего исследования состояла в оценке капилляроскопии и вариабельности сердечного ритма у детей с аллергическим ринитом (АР) в зависимости от наличия коморбидной патологии. Все дети были распределены на три группы: основную – 29 детей с АР в сочетании с герпетической инфекцией и (или) наличием патогенной микрофлоры в мазках из носоглотки в количестве более 106 , группу сравнения – 23 ребенка с АР, контрольную – 26 здоровых детей. Увсех детей с АР имелись выраженные изменения в микроциркуляторном русле, которые варьировали, в зависимости от наличия сопутствующей патологии, наряду с реактивными изменениями вегетативных регуляторных систем в сторону увеличения доминирования центральных механизмов регуляции и преобладания парасимпатического тонуса. У детей с АР с сопутствующей патологией не отмечено выраженного парасимпатического влияния в отличие от детей с АР и детей без сопутствующей патологии, что следует учитывать при составлении плана персонифицированного лечения и реабилитации. </p></abstract><trans-abstract xml:lang="en"><p>Microcirculation mechanisms and vegetative-vascular mechanisms have an important pathogenetic significance in the development of allergic inflammation.</p><p>The purpose of our study was to assess capillaroscopy and heart rate variability in children with allergic rhinitis (AR), depending on the presence of comorbid pathology. All children were divided into three groups: the main group – 29 children with AR in combination with herpes infection or the presence of pathogenic microflora in nasopharyngeal swabs in the amount of more than 106, the comparison group – 23 children with AR, the control group – 26 healthy children. All children with AR had pronounced changes in the microvasculature, which varied depending on the presence of concomitant pathology, along with reactive changes in autonomic regulatory systems towards an increase in the dominance of central regulation mechanisms and the predominance of parasympathetic tone. Children with AR and concomitant pathology did not have a pronounced parasympathetic effect, in contrast to children with AR and children without concomitant pathology, which should be taken into account when drawing up a plan for personalized treatment and rehabilitation. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>аллергический ринит</kwd><kwd>микроциркуляция</kwd><kwd>вегетативная нервная система</kwd></kwd-group><kwd-group xml:lang="en"><kwd>allergic rhinitis</kwd><kwd>microcirculation</kwd><kwd>autonomic nervous system</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Akdis C. A., Hellings P. W., Agache I. Global atlas of allergic rhinitis and chronic rhinosinusitis. 2015, 422.</mixed-citation><mixed-citation xml:lang="en">Akdis C. A., Hellings P. W., Agache I. 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