medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2020-19-6-10medalphabet-1705Research ArticleСтатьиСиндром старческой астении у пациентов с ишемической болезнью сердцаFrailty syndrome in patients with coronary artery diseaseКривошаповаК. Е.KrivoshapovaK. E.

к.м.н., н.с. лаборатории коморбидности при сердечно-сосудистых заболеваниях

г. Кемерово

ВегнерЕ. А.VegnerE. A.

аспирант кафедры кардиологии и сердечно-сосудистой хирургии

г. Кемерово

ТерентьеваН. А.TerentyevaN. A.

аспирант

г. Кемерово

МасенкоВ. Л.MasenkoV. L.

к.м.н., н.с. лаборатории лучевых методов диагностики

г. Кемерово

ГригорьеваИ. И.GrigoryevaI. I.

аспирант кафедры пропедевтики внутренних болезней

г. Кемерово

КоковА. Н.KokovA. N.

зав. лабораторией лучевых методов диагностики

г. Кемерово

БаздыревЕ. Д.BazdyrevE. D.

д.м.н., зав. лабораторией эпидемиологии сердечно-сосудистых заболеваний отдела оптимизации медицинской помощи при сердечно-сосудистых заболеваниях

г. Кемерово

РаскинаТ. А.RaskinaT. A.

д.м.н., проф., зав. кафедрой пропедевтики внутренних болезней

г. Кемерово

БарбарашО. Л.BarbarashO. L.

д.м.н., проф., чл.-корр. РАН, директор; зав. кафедрой кардиологии и сердечно-сосудистой хирургии

г. Кемерово

ФГБНУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»РоссияResearch Institute for Complex Issues of Cardiovascular DiseasesRussian FederationФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава РоссииРоссияKemerovo State Medical UniversityRussian FederationФГБНУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»; ФГБОУ ВО «Кемеровский государственный медицинский университет» Минздрава РоссииРоссияResearch Institute for Complex Issues of Cardiovascular Diseases; Kemerovo State Medical UniversityRussian Federation202002112020119Коморбидные состояния (1)610Copyright © Кривошапова К.Е., Вегнер Е.А., Терентьева Н.А., Масенко В.Л., Григорьева И.И., Коков А.Н., Баздырев Е.Д., Раскина Т.А., Барбараш О.Л., 20202020Кривошапова К.Е., Вегнер Е.А., Терентьева Н.А., Масенко В.Л., Григорьева И.И., Коков А.Н., Баздырев Е.Д., Раскина Т.А., Барбараш О.Л.Krivoshapova K.E., Vegner E.A., Terentyeva N.A., Masenko V.L., Grigoryeva I.I., Kokov A.N., Bazdyrev E.D., Raskina T.A., Barbarash O.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/1705

Цель исследования. Оценить частоту выявления и клинические особенности пациентов с синдромом старческой астении (ССА) при стабильной ишемической болезни сердца (ИБС). Материал и методы. В представленной работе проанализированы данные 387 пациентов, поступивших в клинику с целью проведения планового первичного коронарного шунтирования. Анализировались клинические, анамнестические данные, результаты инструментальных методов исследования. Первичный скрининг преастении и ССА у пациентов перед проведением хирургического вмешательства был произведен с помощью опросника «Возраст не помеха». Статистическая обработка результатов исследования проводилась с помощью пакета программ IBM SPSS Statistics 26.0.0. Различия считались статистически значимыми при р ≤ 0,050. Результаты. У 19% пациентов с ИБС и многососудистым поражением коронарного русла перед проведением открытой реваскуляризации миокарда выявляется ССА, при этом 58% пациентов имеют критерии преастении. Наличие данных состояний ассоциировалось с такими факторами риска, как пожилой и старческий возраст (р = 0,003), женский пол (р = 0,001), сахарный диабет второго типа (р = 0,006), а также с такими коморбидными состояниями, как церебральный атеросклероз (р = 0,020), нарушения ритма сердца (р = 0,050). Выводы. Полученные в настоящем исследовании результаты свидетельствуют о более высоком уровне коморбидности «хрупких» пациентов.

Aim. To assess the prevalence of frailty and describe clinical features of frail patients with stable coronary artery disease (CAD). Methods. 387 patients admitted to the hospital for elective primary coronary artery bypass grafting (CABG) were recruited in the study. Clinical data, demographic data, and the results of the instrumental examinations were collected for each subject. The primary screening of prefrailty and frailty in patients before the surgery was performed using the ’Age is not a hindrance’ questionnaire. The results were processed using the IBM SPSS Statistics 26.0.0 software package. A value of p ≤ 0.050 was considered statistically significant. Results. Frailty was found in 19% of patients with coronary artery disease and multivessel coronary artery disease before open myocardial revascularization, while 58% of patients had prefrailty. The presence of frailty and prefrailty was associated with older and advanced age (p = 0.003), female sex (p = 0.001), type 2 diabetes mellitus (p = 0.006), as well as with comorbidities, including cerebral atherosclerosis (p = 0.020), and heart rhythm disturbances (p = 0.050). Conclusion. The results obtained in this study are consistent with other studies reporting higher levels of comorbidities among frail patients.

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The authors declare that there are no conflicts of interest present.