<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-17</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Современные возможности методов нейровизуализации в исследовании двигательной системы и в клинической практике</article-title><trans-title-group xml:lang="en"><trans-title>Modern possibilities of neuroimaging methods in the motor control system research and in clinical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Екушева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ekusheva</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Moscow State Medical University n.a. I.M. Sechenov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>19</day><month>01</month><year>2017</year></pub-date><volume>1</volume><issue>2</issue><issue-title>Неврология и психиатрия</issue-title><fpage>18</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Екушева Е.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Екушева Е.В.</copyright-holder><copyright-holder xml:lang="en">Ekusheva E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/17">https://www.med-alphabet.com/jour/article/view/17</self-uri><abstract><p>Двигательная система отличается сложной организацией, при этом анализ и понимание интегративных механизмов, лежащих в основе осуществления разнообразных моторных актов, продолжают оставаться актуальными и до конца не решенными проблемами. В статье обсуждаются наиболее распространенные методы исследования двигательной системы, преимущества использования и различные диагностические возможности.</p></abstract><trans-abstract xml:lang="en"><p>Motor system characterized by the complex organization, with the analysis and understanding of integrative mechanisms underlying the implementation of a variety of motor acts continue to be valid until the end of the unsolved problems. The article discusses the most common methods of investigation of the motor system, in particular, how they work, and the advantages of using different diagnostic possibilities.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>двигательная система</kwd><kwd>магнитно-резонансная томография</kwd><kwd>транскраниальная магнитная стимуляция</kwd><kwd>позитронно-эмиссионная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>motor system</kwd><kwd>magnetic resonance imaging</kwd><kwd>transcranial magnetic stimulation</kwd><kwd>positron emission tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Никитин С.С., Куренков А.А. Магнитная стимуляция в диагностике и лечении болезней нервной системы: руководство для врачей / С.С. Никитин, А.А. Куренков. - М.: САШКО, 2003. - 378 с.</mixed-citation><mixed-citation xml:lang="en">Никитин С.С., Куренков А.А. Магнитная стимуляция в диагностике и лечении болезней нервной системы: руководство для врачей / С.С. Никитин, А.А. Куренков. - М.: САШКО, 2003. - 378 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Haas B. Motor Control. In: T. Everett, C. Kell (eds.). Human Movement. Edinburgh: Churchill, Livingstone. 2010: 47-60.</mixed-citation><mixed-citation xml:lang="en">Haas B. Motor Control. In: T. Everett, C. Kell (eds.). Human Movement. Edinburgh: Churchill, Livingstone. 2010: 47-60.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Bonaiuti D., Grimaldi M. Neuroimaging: a new challenge in neurorehabilitation of stroke patients. Eura. Medicophys. 2007; 43 (2): 215-219.</mixed-citation><mixed-citation xml:lang="en">Bonaiuti D., Grimaldi M. Neuroimaging: a new challenge in neurorehabilitation of stroke patients. Eura. Medicophys. 2007; 43 (2): 215-219.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Добрынина А.А. Возможности функциональной и структурной нейровизуализации в изучении восстановления двигательных функций после ишемического инсульта. Анналы неврологии. 2011; 5 (3): 53-61.</mixed-citation><mixed-citation xml:lang="en">Добрынина А.А. Возможности функциональной и структурной нейровизуализации в изучении восстановления двигательных функций после ишемического инсульта. Анналы неврологии. 2011; 5 (3): 53-61.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Меллер Т.Б., Райф Э. Укладки и режимы при магнитно-резонансной томографии. Пер. с нем. Под общ. ред. Ш.Ш. Шотемора. - М.: МЕДпресс-информ, 2008. - 232 с.</mixed-citation><mixed-citation xml:lang="en">Меллер Т.Б., Райф Э. Укладки и режимы при магнитно-резонансной томографии. Пер. с нем. Под общ. ред. Ш.Ш. Шотемора. - М.: МЕДпресс-информ, 2008. - 232 с.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Труфанов Г.Е. Лучевая диагностика. М.: ГЭОТАР-Медиа, 2011. - 416 с.</mixed-citation><mixed-citation xml:lang="en">Труфанов Г.Е. Лучевая диагностика. М.: ГЭОТАР-Медиа, 2011. - 416 с.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Moser E., Meyerspeer M., Fischmeister F. et. al. Windows on the human body - in vivo highfield magnetic resonance research and applications in medicine and psychology. Sensors (Basel). 2010; 10 (6): 5724-5757.</mixed-citation><mixed-citation xml:lang="en">Moser E., Meyerspeer M., Fischmeister F. et. al. Windows on the human body - in vivo highfield magnetic resonance research and applications in medicine and psychology. Sensors (Basel). 2010; 10 (6): 5724-5757.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Copen W.A., Lev M.H. Acute ischemic stroke: an evidence-based approach. Eds. by D.G. Greer. Willey-Liss; 2007: 3-39.</mixed-citation><mixed-citation xml:lang="en">Copen W.A., Lev M.H. Acute ischemic stroke: an evidence-based approach. Eds. by D.G. Greer. Willey-Liss; 2007: 3-39.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Jang S.H. The role of the corticospinal tract in motor recovery in patients with a stroke: а review. Neuro Rehabilitation. 2009; 24 (3): 285-290.</mixed-citation><mixed-citation xml:lang="en">Jang S.H. The role of the corticospinal tract in motor recovery in patients with a stroke: а review. Neuro Rehabilitation. 2009; 24 (3): 285-290.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Perez M.A., Cohen L G. The corticospinal system and transcranial magnetic stimulation in stroke. Top. Stroke Rehabil. 2009; 16 (4): 254-269.</mixed-citation><mixed-citation xml:lang="en">Perez M.A., Cohen L G. The corticospinal system and transcranial magnetic stimulation in stroke. Top. Stroke Rehabil. 2009; 16 (4): 254-269.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Stinear C.M., Barber P.A., Smale P.R. et.al. Functional potential in chronic stroke patients depends on corticospinal tract integrity. Brain. 2007; 130: 170-180.</mixed-citation><mixed-citation xml:lang="en">Stinear C.M., Barber P.A., Smale P.R. et.al. Functional potential in chronic stroke patients depends on corticospinal tract integrity. Brain. 2007; 130: 170-180.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Lee J.S., Han M-K., Kim S.H. et al. Fiber tracking by diffusion tensor imaging in corticospinal tract stroke: Topographical correlation with clinical symptoms. Neuro Image. 2005; 26: 771-776.</mixed-citation><mixed-citation xml:lang="en">Lee J.S., Han M-K., Kim S.H. et al. Fiber tracking by diffusion tensor imaging in corticospinal tract stroke: Topographical correlation with clinical symptoms. Neuro Image. 2005; 26: 771-776.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Basser P.J., Pierpaoli C. Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J. Magn. Reson. B. 1996; 111: 209-219.</mixed-citation><mixed-citation xml:lang="en">Basser P.J., Pierpaoli C. Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J. Magn. Reson. B. 1996; 111: 209-219.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Konishi J., Yamada K., Kizu O. et al. MR tractography for the evaluation of functional recovery from lenticulostriate infarcts. Neurology. 2005; 64: 108-113.</mixed-citation><mixed-citation xml:lang="en">Konishi J., Yamada K., Kizu O. et al. MR tractography for the evaluation of functional recovery from lenticulostriate infarcts. Neurology. 2005; 64: 108-113.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Bruno A.A. Motor recovery in stroke. In: Physical Medicine and Rehabilitation. M. J. Klein et al. (eds.). Medicine; 2002: 452-489.</mixed-citation><mixed-citation xml:lang="en">Bruno A.A. Motor recovery in stroke. In: Physical Medicine and Rehabilitation. M. J. Klein et al. (eds.). Medicine; 2002: 452-489.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Deichmann R., Nöth U., Weiskopf N. The basic of functional magnetic resonance imaging. EEG-fMRI. Physiological basis, technique and applications. Eds. Mulert C., Lemieux L. Springer-Verlag Berlin Heidelberg, 2010: 39-62.</mixed-citation><mixed-citation xml:lang="en">Deichmann R., Nöth U., Weiskopf N. The basic of functional magnetic resonance imaging. EEG-fMRI. Physiological basis, technique and applications. Eds. Mulert C., Lemieux L. Springer-Verlag Berlin Heidelberg, 2010: 39-62.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Schmuel A. Locally measured neuronal correlates of functional MRI signals. EEG-fMRI. Physiological basis, technique and applications. Eds. Mulert C., Lemieux L. Springer-Verlag Berlin Heidelberg, 2010: 63-82.</mixed-citation><mixed-citation xml:lang="en">Schmuel A. Locally measured neuronal correlates of functional MRI signals. EEG-fMRI. Physiological basis, technique and applications. Eds. Mulert C., Lemieux L. Springer-Verlag Berlin Heidelberg, 2010: 63-82.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ward N.S. Future perspectives in functional neuroimaging in stroke recovery. Eura. Medicophys. 2007; 43: 285-294.</mixed-citation><mixed-citation xml:lang="en">Ward N.S. Future perspectives in functional neuroimaging in stroke recovery. Eura. Medicophys. 2007; 43: 285-294.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Matthews P.M., Honey G.D., Bullmore E.T. Applications of fMRI in translational medicine and clinical practice. Nat. Rev. Neurosci. 2006; 7: 732-744.</mixed-citation><mixed-citation xml:lang="en">Matthews P.M., Honey G.D., Bullmore E.T. Applications of fMRI in translational medicine and clinical practice. Nat. Rev. Neurosci. 2006; 7: 732-744.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Logothetis N.K. What we can do and what we cannot do with fMRI. Nature. 2008; 453 (12): 869-878.</mixed-citation><mixed-citation xml:lang="en">Logothetis N.K. What we can do and what we cannot do with fMRI. Nature. 2008; 453 (12): 869-878.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Rossini P.M., Burke D., Chen R. et al. Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee. Clinical Neurophysiology. 2015; 126: 1071-1107.</mixed-citation><mixed-citation xml:lang="en">Rossini P.M., Burke D., Chen R. et al. Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee. Clinical Neurophysiology. 2015; 126: 1071-1107.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Romero J.R., Anschel D., Sparing R., Gangitano M., Pascual-Leone A., Subthreshold low frequency repetitive transcranial magnetic stimulation selectively decreases facilitation in the motor cortex. Clin. Neurophysiol. 2002; 113(1): 101-107.</mixed-citation><mixed-citation xml:lang="en">Romero J.R., Anschel D., Sparing R., Gangitano M., Pascual-Leone A., Subthreshold low frequency repetitive transcranial magnetic stimulation selectively decreases facilitation in the motor cortex. Clin. Neurophysiol. 2002; 113(1): 101-107.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Екушева Е.В. Использование транскраниальных ответов для анализа степени вовлечения верхнего мотонейрона в патологический процесс у больных рассеянным склерозом. Врач-аспирант. 2011; 1.1 (44): 153-161.</mixed-citation><mixed-citation xml:lang="en">Екушева Е.В. Использование транскраниальных ответов для анализа степени вовлечения верхнего мотонейрона в патологический процесс у больных рассеянным склерозом. Врач-аспирант. 2011; 1.1 (44): 153-161.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Talelli P., Rothwell J. Does brain stimulation after stroke have a future? Curr. Opin. Neurol. 2006; 19: 543-550.</mixed-citation><mixed-citation xml:lang="en">Talelli P., Rothwell J. Does brain stimulation after stroke have a future? Curr. Opin. Neurol. 2006; 19: 543-550.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Shimizu T., Hosaki A., Hino T. et al. Motor cortical disinhibition in the unaffected hemisphere after unilateral cortical stroke. Brain. 2002; 125: 1896-1907.</mixed-citation><mixed-citation xml:lang="en">Shimizu T., Hosaki A., Hino T. et al. Motor cortical disinhibition in the unaffected hemisphere after unilateral cortical stroke. Brain. 2002; 125: 1896-1907.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Дамулин И.В. Особенности структурной и функциональной организации головного мозга. Журнал невр. и психиатр. им. Корсакова. 2016; 11: 163-168.</mixed-citation><mixed-citation xml:lang="en">Дамулин И.В. Особенности структурной и функциональной организации головного мозга. Журнал невр. и психиатр. им. Корсакова. 2016; 11: 163-168.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Bestmann S., Swayne O., Blankenburg F.et.al. Dorsal premotor cortex exerts state-dependent causal influences on activity in contralateral primary motor and dorsal premotor cortex. Cereb. Cortex. 2008; 18 (6): 1281-1291.</mixed-citation><mixed-citation xml:lang="en">Bestmann S., Swayne O., Blankenburg F.et.al. Dorsal premotor cortex exerts state-dependent causal influences on activity in contralateral primary motor and dorsal premotor cortex. Cereb. Cortex. 2008; 18 (6): 1281-1291.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
