medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2020-20-30-33medalphabet-1650Research ArticleСтатьиНеоадъювантная терапия рака молочной железы. Значение резидуальной болезниNeoadjuvant therapy for breast cancer. Value of residual diseaseКоваленкоЕ. И.KovalenkoE. I.

Кандидат медицинских наук, старший научный сотрудник онкологического отделения лекарственных методов лечения (химиотерапевтического) № 1.

Москва

Moscow

АртамоноваЕ. В.ArtamonovaE. V.

Доктор медицинских наук, профессор, зав. онкологическим отделением лекарственных методов лечения (химиотерапевтическим) № 11, профессор кафедры онкологии и лучевой терапии.

Москва

Russian National Research Medical University n.a. N.I. Pirogov

ФГБУ «Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина» Минздрава РоссииРоссияNational Medical Research Centre of Oncology n.a. N.N. BlokhinRussian FederationФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н. И. Пирогова» Минздрава РоссииРоссияMoscowRussian Federation202010102020020Диагностика и онкотерапия (2)3033Copyright © Коваленко Е.И., Артамонова Е.В., 20202020Коваленко Е.И., Артамонова Е.В.Kovalenko E.I., Artamonova E.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/1650

Лекарственное лечение является неотъемлемой частью комплексного подхода при раннем и местнораспространенном раке молочной железы. В статье рассмотрены основные цели и принципы неоадъювантной химиотерапии при различных подтипах рака молочной железы, взаимосвязь между полной патоморфологической регрессией и отдаленными результатами, подходы к терапии резидуальной болезни. Унифицированная оценка остаточной опухоли по системе RCB после проведенной неоадъювантной химиотерапии позволяет четко выделить прогностические группы пациентов с различным ответом на лечение и в свою очередь планировать им дополнительную лекарственную терапию.

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The authors declare that there are no conflicts of interest present.