medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2020-16-51-53medalphabet-1614Research ArticleСтатьиЗуд беременных: причины и коррекция состоянийPruritus gravidarum: causes and correction of conditionsДворянковаЕ. В.DvoryankovaE. V.

д.м.н., в.н.с.

НевозинскаяЗ. А.NevozinskayaZ. A.

к.м.н., врач-дерматовенеролог

КорсунскаяИ. М.KorsunskayaI. M.

д.м. н, проф., зав. лабораторией

ФГБУН «Центр теоретических проблем физико-химической фармакологии» Российской академии наукРоссияCentre for Theoretical Problems of Physicochemical PharmacologyRussian FederationГБУЗ г. Москвы «Московский научно-практический центр дерматовенерологии и косметологии» Департамента здравоохранения г. МосквыРоссияMoscow Scientific and Practical Centre for Dermatovenereology and CosmetologyRussian Federation202021092020016Современная гинекология (2)5153Copyright © Дворянкова Е.В., Невозинская З.А., Корсунская И.М., 20202020Дворянкова Е.В., Невозинская З.А., Корсунская И.М.Dvoryankova E.V., Nevozinskaya Z.A., Korsunskaya I.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/1614

Кожный зуд может встречаться у до 20% беременных. В работе рассматриваются наиболее частые причины развития этого неприятного симптома у женщин, ожидающих ребенка, такие как полиморфный и атопический дерматиты, внутрепечоночный холестаз, пемфигоид. Приводятся современные эпидемиологические данные, описаны особенности клинической картины каждой нозологии, и даны рекомендации по эффективной терапии данных состояний.

Itching sensation can occur in up to 20% of pregnant women. The paper considers the most common causes of the development of this unpleasant symptom in women expecting a baby, such as polymorphic and atopic dermatitis, intrahepatic cholestasis, pemphigoid. Modern epidemiological data are presented, the clinical features of each nosology are described, and recommendations for effective treatment of these conditions are given.

зуд беременныхполиморфный дерматит беременныхпемфигоид беременныхатопический дерматит беременныхвнутрипеченочный холестазpruritus gravidarumpregnant polymorphic dermatitispregnant pemphigoidpregnant atopic dermatitisintrahepatic cholestasisReferencesMeta N, Chen K, Kroumpouzos G. Skin disease in pregnancy: the approach of the obstetric medicine physician. Clin Dermatol 2016; 34: 320–6.Meta N, Chen K, Kroumpouzos G. Skin disease in pregnancy: the approach of the obstetric medicine physician. Clin Dermatol 2016; 34: 320–6.Bechtel M, Plotner A. Dermatoses of pregnancy. Clin Obstet Gynecol 2015; 58: 104–11.Bechtel M, Plotner A. Dermatoses of pregnancy. Clin Obstet Gynecol 2015; 58: 104–11.Rudolph CM, Al-Fares S, Vaughan-Jones SA, et al. Polymorphic eruption of pregnancy: clinicopathology and potential trigger factors in 181 patients. Br J Dermatol 2006; 154: 54–60.Rudolph CM, Al-Fares S, Vaughan-Jones SA, et al. Polymorphic eruption of pregnancy: clinicopathology and potential trigger factors in 181 patients. Br J Dermatol 2006; 154: 54–60.Lambert J. Pruritus in female patients. Biomed Res Int 2014; 2014: 1–6.Lambert J. Pruritus in female patients. Biomed Res Int 2014; 2014: 1–6.Vaughan-Jones SA, Hern S, Nelson-Piercy C, et al. A prospective study of 200 women with dermatoses of pregnancy correlating clinical findings with hormonal and immunopathological profiles. Br J Dermatol 1999; 141: 71–81.Vaughan-Jones SA, Hern S, Nelson-Piercy C, et al. A prospective study of 200 women with dermatoses of pregnancy correlating clinical findings with hormonal and immunopathological profiles. Br J Dermatol 1999; 141: 71–81.Ambrose-Rudolf CM. Dermatoses of pregnancy to diagnosis, fetal risk, and therapy. Ann Dermatol 2011; 23: 265–75.Ambrose-Rudolf CM. Dermatoses of pregnancy to diagnosis, fetal risk, and therapy. Ann Dermatol 2011; 23: 265–75.Beard MP, Millington GW. Recent developments in the specific dermatoses of pregnancy. Clin Exp Dermatol 2012; 37: 1–14.Beard MP, Millington GW. Recent developments in the specific dermatoses of pregnancy. Clin Exp Dermatol 2012; 37: 1–14.Lehrhoff S, Pomeranz MK. Specific dermatoses of pregnancy and their treatment. Dermatol Ther 2015; 26: 274–84.Lehrhoff S, Pomeranz MK. Specific dermatoses of pregnancy and their treatment. Dermatol Ther 2015; 26: 274–84.Ambrose-Rudolph CM, Mu llegger RR, VaughanJones SA, et al. The specific dermatoses of pregnancy revisited and reclassified: results of a retrospective two-center study on 505 pregnant patients. J Am Acad Dermatol 2006; 54: 395–404.Ambrose-Rudolph CM, Mu llegger RR, VaughanJones SA, et al. The specific dermatoses of pregnancy revisited and reclassified: results of a retrospective two-center study on 505 pregnant patients. J Am Acad Dermatol 2006; 54: 395–404.Dixon PH. The pathophysiology in intrahepatic cholestasis of pregnancy. Clin Res Hepatol Gastroenterol 2016; 40 (2): 141–53.Dixon PH. The pathophysiology in intrahepatic cholestasis of pregnancy. Clin Res Hepatol Gastroenterol 2016; 40 (2): 141–53.Lammert F, Marschall HU, Matern S. Intrahepatic cholestasis of pregnancy, molecular pathogenesis, diagnosis, and management. J Hepatol 2000; 33: 1012–21.Lammert F, Marschall HU, Matern S. Intrahepatic cholestasis of pregnancy, molecular pathogenesis, diagnosis, and management. J Hepatol 2000; 33: 1012–21.Bergman H, Melamed N, Koren G. Pruritus in pregnancy: treatment of dermatoses unique to pregnancy. Can Fam Physician 2013; 59 (12): 1290–4.Bergman H, Melamed N, Koren G. Pruritus in pregnancy: treatment of dermatoses unique to pregnancy. Can Fam Physician 2013; 59 (12): 1290–4.Geenes V, Chappell LC, Seed PT, et al. Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-controlled study. Hepatology 2014; 59: 1482–91.Geenes V, Chappell LC, Seed PT, et al. Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-controlled study. Hepatology 2014; 59: 1482–91.Lehrhoff S, Pomeranz MK. Specific dermatoses of pregnancy and their treatment. Dermatol Ther 2015; 26: 274–84.Lehrhoff S, Pomeranz MK. Specific dermatoses of pregnancy and their treatment. Dermatol Ther 2015; 26: 274–84.

The authors declare that there are no conflicts of interest present.