References

medalphabet

Медицинский алфавит

Medical alphabet

2078-56312949-2807

ООО «Альфмед»

medalphabet-158

Research Article

Статьи

Роль антимюллерова гормона в женской репродукции

Role of anti-müllerian hormone in female reproduction

Кузнецова

И. В.

Kuznetsova

I. V.

noemail@neicon.ru

Драпкина

Ю. С.

Drapkina

Yu. S.

noemail@neicon.ru

ФГБОУ ВО «Первый Московский государственный медицинский университет имени И. М. Сеченова» Минздрава РоссииРоссияFirst Moscow State Medical University n.a. I. M. SechenovRussian Federation

2017

01042017

210

Современная гинекология

916

2017

Кузнецова И.В., Драпкина Ю.С.

Kuznetsova I.V., Drapkina Y.S.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.med-alphabet.com/jour/article/view/158

Антимюллеров гормон (АМГ) является одним из наиболее изучаемых в настоящее время биологически активных соединений. Его роль в процессах женской репродукции признается весьма значительной, но конкретные функции, механизмы их осуществления и регуляция образования самого АМГ остаются предметом исследований. В клинической практике определение уровней АМГ применимо в контексте предсказания ответа яичников на стимуляцию в программах вспомогательных репродуктивных технологий, а также для прогнозирования преждевременной овариальной недостаточности у женщин, подвергающихся терапии, потенциально токсичной для яичников. Одним из перспективных направлений является оценка уровня АМГ как способ прогнозирования и диагностики синдрома поликистозных яичников. Лекарственная терапия может оказать существенное влияние на синтез и секрецию АМГ. В качестве средства, прямо и опосредованно позитивно воздействующих на уровень АМГ выделяются аналоги гонадолиберина.

Anti-müllerian hormone (AMH) is one of the most studied at the present time biologically active compounds. Its role in the processes of female reproduction is recognized as very significant, but specific functions, mechanisms for their implementation and regulation of the formation of the AMH itself remain the subject of research. In clinical practice, the determination of AMH levels is applicable in the context of predicting the response of ovaries to stimulation in assisted reproductive technology programs, as well as for predicting premature ovarian failure in women undergoing therapy potentially toxic to the ovaries. One of the promising areas is the assessment of the level of AMH as a method for predicting and diagnosing the polycystic ovary syndrome. Drug therapy can have a significant effect on the synthesis and secretion of AMH. As an agent directly and indirectly positively affecting the level of AMH, gonadoliberin analogues are isolated.

антимюллеров гормонфолликулогенезовуляцияовариальный резервконтролируемая индукция овуляцииожирениесиндром поликистозных яичниковпреждевременная недостаточность яичниковэндометриозаналоги гонадолиберина

anti-müllerian hormonefolliculogenesisovulationovarian reservecontrolled induction of ovulationobesitypolycystic ovary syndromepremature ovarian failureendometriosisgonadoliberin analogues

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The authors declare that there are no conflicts of interest present.