<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-151</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Возможности лучевой терапии в лечении пациентов с метастатическим поражением позвонков, вызывающим компрессию спинного мозга</article-title><trans-title-group xml:lang="en"><trans-title>Potential of radiotherapy in treatment of patients with metastatic vertebral lesions, causing compression of spinal cord</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачев</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkachyov</surname><given-names>S. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романов</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanov</surname><given-names>D. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимошкина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Timoshkina</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Валиев</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Valiev</surname><given-names>A. K.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Назаренко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nazarenko</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глебовская</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Glebovskaya</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трофимова</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Trofimova</surname><given-names>O. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисова</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisova</surname><given-names>T. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федосеенко</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedoseenko</surname><given-names>D. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведев</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedev</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Российский онкологический научный центр имени Н.Н. Блохина» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Oncological Scientific Centre n.a. N.N. Blokhin</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский научно-исследовательский институт имени П.А. Герцена - филиал ФГБУ «Национальный медицинский исследовательский радиологический центр» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute n.a. P.A. Herzen - a Branch of National Medical Radiological Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>25</day><month>05</month><year>2017</year></pub-date><volume>1</volume><issue>16</issue><issue-title>Диагностика и онкотерапия</issue-title><fpage>42</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ткачев С.И., Романов Д.С., Тимошкина Е.В., Валиев А.К., Назаренко А.В., Глебовская В.В., Трофимова О.П., Борисова Т.Н., Федосеенко Д.И., Медведев С.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Ткачев С.И., Романов Д.С., Тимошкина Е.В., Валиев А.К., Назаренко А.В., Глебовская В.В., Трофимова О.П., Борисова Т.Н., Федосеенко Д.И., Медведев С.В.</copyright-holder><copyright-holder xml:lang="en">Tkachyov S.I., Romanov D.S., Timoshkina E.V., Valiev A.K., Nazarenko A.V., Glebovskaya V.V., Trofimova O.P., Borisova T.N., Fedoseenko D.I., Medvedev S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/151">https://www.med-alphabet.com/jour/article/view/151</self-uri><abstract><p>Синдром компрессии спинного мозга - тяжелое осложнение метастатического поражения позвоночного столба у онкологических больных. Отсутствие специфического лечения или неэффективность такого лечения ведут к развитию нарушения чувствительной и двигательной функций конечностей, нарушения функции тазовых органов, выраженного болевого синдрома. Своевременно проведенный курс дистанционной лучевой терапии в самостоятельном режиме или составе комплексной терапии позволяет предотвратить инвалидизацию пациента и значительно повысить качество его жизни. В данной статье приведены два примера успешного лечения пациентов с синдромом компрессии спинного мозга с применением дистанционной лучевой терапии в составе комплексного лечения.</p></abstract><trans-abstract xml:lang="en"><p>Spinal cord compression syndrome is a serious complication of metastatic lesions of the spine in patients with cancer. No specific treatment or ineffectiveness of such treatment lead to the development of sensory disturbances and motor functions of limbs, pelvic organ dysfunction, severe pain syndrome. Timely conducted course of external beam radiotherapy in separate mode or complex therapy prevents the patient s disability, and significantly improve the quality of life. This article provides two examples of the successful treatment of patients with spinal cord compression syndrome with the use of external beam radiation therapy as part of comprehensive treatment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>компрессия спинного мозга</kwd><kwd>дистанционная лучевая терапия</kwd><kwd>восстановление функции нижних конечностей</kwd></kwd-group><kwd-group xml:lang="en"><kwd>spinal cord compression</kwd><kwd>external beam radiotherapy</kwd><kwd>efficiency</kwd><kwd>lower limbs function recover</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">А. К. Валиев, Э. Р. Мусаев, Е. А. Сушенцов, К. А. Борзов. Чрескожная вертебропла-стика при метастатическом поражении позвоночника. Саркомы костей, мягких тканей и опухоли кожи. 2009, № 1, стр. 23-27.</mixed-citation><mixed-citation xml:lang="en">А. К. Валиев, Э. Р. Мусаев, Е. А. Сушенцов, К. А. Борзов. Чрескожная вертебропла-стика при метастатическом поражении позвоночника. Саркомы костей, мягких тканей и опухоли кожи. 2009, № 1, стр. 23-27.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">В. М. Моисеенко, Н. Н. Блинов. Современная тактика лечения больных злокачественными новообразованиями с метастазами в кости (пособие для врачей). СПб., 1996.</mixed-citation><mixed-citation xml:lang="en">В. М. Моисеенко, Н. Н. Блинов. Современная тактика лечения больных злокачественными новообразованиями с метастазами в кости (пособие для врачей). СПб., 1996.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">R. E. Coleman. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin. Cancer Res. 2006; 12 (20 suppl.) 6243s-6249s.</mixed-citation><mixed-citation xml:lang="en">R. E. Coleman. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin. Cancer Res. 2006; 12 (20 suppl.) 6243s-6249s.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">А. С. Жабина. Роль бисфосфонатов для профилактики и лечения метастазов в кости. Практическая онкология. Т. 12, № 3. - 2011.</mixed-citation><mixed-citation xml:lang="en">А. С. Жабина. Роль бисфосфонатов для профилактики и лечения метастазов в кости. Практическая онкология. Т. 12, № 3. - 2011.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">W. Boogerd, J. J. van der Sande. Diagnosis and treatment of spinal cord compression in malign.</mixed-citation><mixed-citation xml:lang="en">W. Boogerd, J. J. van der Sande. Diagnosis and treatment of spinal cord compression in malign.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">K. Tomita, N. Kawahara, T. Kobayashi, et al. Surgical strategy for spinal metastases. Spine (Phila. Pa. 1976). 2001 Feb 1; 26 (3): 298-306.</mixed-citation><mixed-citation xml:lang="en">K. Tomita, N. Kawahara, T. Kobayashi, et al. Surgical strategy for spinal metastases. Spine (Phila. Pa. 1976). 2001 Feb 1; 26 (3): 298-306.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Metastatic Spinal Cord Compression. Diagnosis and Management of Patients at Risk of or with Metastatic Spinal Cord Compression. NICE Clinical Guidelines, No. 75. National Collaborating Centre for Cancer (UK). Cardiff (UK): National Collaborating Centre for Cancer (UK); 2008 Nov. ISBN-13: 978-0-9558265-1-1.</mixed-citation><mixed-citation xml:lang="en">Metastatic Spinal Cord Compression. Diagnosis and Management of Patients at Risk of or with Metastatic Spinal Cord Compression. NICE Clinical Guidelines, No. 75. National Collaborating Centre for Cancer (UK). Cardiff (UK): National Collaborating Centre for Cancer (UK); 2008 Nov. ISBN-13: 978-0-9558265-1-1.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">R. Patchell, P. A. Tibbs, W. F. Regine et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomized trial. Lancet 366. 2005. 643-648.</mixed-citation><mixed-citation xml:lang="en">R. Patchell, P. A. Tibbs, W. F. Regine et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomized trial. Lancet 366. 2005. 643-648.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
