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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-15</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Особенности медикаментозной терапии болевого синдрома у пациентов с терминальной почечной недостаточностью, получающих терапию хрониогемодиализом</article-title><trans-title-group xml:lang="en"><trans-title>Features of medication therapy of pain syndrome in patients with end-stage renal disease receiving treatment with chronic hemodialysis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прилепская</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Prilepskaya</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дурова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Durova</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Тюменский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>19</day><month>01</month><year>2017</year></pub-date><volume>1</volume><issue>2</issue><issue-title>Неврология и психиатрия</issue-title><fpage>9</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Прилепская О.А., Дурова М.В., Лебедев И.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Прилепская О.А., Дурова М.В., Лебедев И.А.</copyright-holder><copyright-holder xml:lang="en">Prilepskaya O.A., Durova M.V., Lebedev I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/15">https://www.med-alphabet.com/jour/article/view/15</self-uri><abstract><p>В статье отражены основные аспекты проблемы противоболевой медикаментозной терапии пациентов с терминальной почечной недостаточностью, получающих хрониогемодиализ. Описаны основные патофизиологические механизмы воздействия лекарственных препаратов на структуры почки. Приведены критерии, которым должно отвечать лекарственное средство, назначаемое с анальгетической целью нефрологическим больным. Проанализированы возможности применения нестероидных противовоспалительных препаратов, антидепрессантов и антиконвульантов в терапии боли среди пациентов с исследуемой патологией. Представлены рекомендации зарубежных сообществ нефрологов по анальгетической терапии у больных с патологией почек.</p></abstract><trans-abstract xml:lang="en"><p>The article describes the major aspects of analgesic drug treatment of pain in patients with endstage renal failure receiving chronic hemodialysis. The basic pathophysiological mechanisms of action of drugs on kidney structure. The criteria to be met by a drug administered with the analgesic purpose of nephrology patients. The possibilities of the use of non-steroidal anti-inflammatory drugs, antidepressants and antikonvulantov in the treatment of pain in patients with the studied disease. Presented recommendations for analgesic therapy in patients with kidney disease of foreign nephrologists’ communities.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>почечная недостаточность</kwd><kwd>боль</kwd><kwd>гемодиализ</kwd><kwd>нестероидные противовоспалительные препараты</kwd><kwd>антидепрессанты</kwd><kwd>противосудорожные препараты в лечении боли</kwd></kwd-group><kwd-group xml:lang="en"><kwd>renal failure</kwd><kwd>pain</kwd><kwd>hemodialysis</kwd><kwd>non-steroidal anti-inflammatory drugs</kwd><kwd>antidepressants</kwd><kwd>anticonvulsants in treatment of pain</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Данилов Ан.Б., Данилов А.Б. Управление болью: биосоциальный подход. 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