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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2020-2-20-23</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-1427</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Современные факторы риска и особенности терапии онихомикоза</article-title><trans-title-group xml:lang="en"><trans-title>Modern risk factors and features of treatment of onychomycosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сакания</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Sakania</surname><given-names>L. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-дерматолог</p><p>г. Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пирузян</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Piruzyan</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н.</p><p>г. Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корсунская</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Korsunskaya</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., проф.</p><p>г. Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ г. Москвы «Московский научно-практический центр дерматовенерологии и косметологии» Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Scientific and Practical Centre for Dermatovenereology and Cosmetology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУН «Центр теоретических проблем физико-химической фармакологии» Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Centre for Theoretical Problems of Physicochemical Pharmacology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>12</day><month>06</month><year>2020</year></pub-date><volume>0</volume><issue>2</issue><issue-title>Современная поликлиника</issue-title><fpage>20</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сакания Л.Р., Пирузян А.Л., Корсунская И.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Сакания Л.Р., Пирузян А.Л., Корсунская И.М.</copyright-holder><copyright-holder xml:lang="en">Sakania L.R., Piruzyan A.L., Korsunskaya I.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/1427">https://www.med-alphabet.com/jour/article/view/1427</self-uri><abstract><p>Онихомикоз является широко распространенным заболеванием ногтей, вызванным дерматофитами, дрожжами и недерматофитами. Факторами риска развития онихомикоза могут выступать различные соматические состояния, к примеру диабет, возраст, особенности образа жизни. Часто онихомикоз встречается у спортсменов. Так, по некоторым данным, у 60,7 % футболистов наблюдается данное заболевание. Причиной повышенного риска развития онихомикозов у спортсменов является ношение неподходящей обуви, частое использование синтетической одежды и обуви, сохраняющей пот, травмы ногтевых пластин. Предпочтение стоит отдавать системной терапии. Лечение может занимать до 18 месяцев, что обусловлено медленным отрастанием здоровой ногтевой пластинки. Из системных препаратов широко применяется итраконазол. Препарат может назначаться по схеме пульс‑терапии, и положительная динамика наблюдается уже через 2 месяца применения.</p></abstract><trans-abstract xml:lang="en"><p>Onychomycosis is a widespread nail disease caused by dermatophytes, yeast and non‑dermatophytes. Risk factors for the development of onychomycosis can be various somatic conditions, for example diabetes, age, lifestyle features. Often onychomycosis occurs in athletes. According to some reports, 60.7 % of football players have this disease. The reason for the increased risk of developing onychomycosis in athletes is wearing unsuitable shoes, the frequent use of synthetic clothing and sweat‑preserving shoes, and injuries to the nail plates. Preference should be given to systemic therapy. Treatment can take up to 18 months, due to the slow regrowth of a healthy nail plate. Of the systemic drugs, itraconazole is widely used. The drug can be prescribed according to the scheme of pulse therapy, and positive dynamics is observed after 2 months of use.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>онихомикоз</kwd><kwd>факторы риска</kwd><kwd>системная терапия</kwd><kwd>итраконазол</kwd></kwd-group><kwd-group xml:lang="en"><kwd>onychomycosis</kwd><kwd>risk factors</kwd><kwd>systemic therapy</kwd><kwd>itraconazole</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Smith E. B. History of antifungals. J. Am. Acad. Dermatol. 1990; 23: 776–778. DOI: 10.1016/0190–9622(90)70286-Q.</mixed-citation><mixed-citation xml:lang="en">Smith E. B. History of antifungals. J. Am. Acad. Dermatol. 1990; 23: 776–778. DOI: 10.1016/0190–9622(90)70286-Q.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Neumann H. A. 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