<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-140</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Альфа-тета континуум: нейрофизиологические механизмы генерации</article-title><trans-title-group xml:lang="en"><trans-title>Alpha-theta continuum: underlying neurophysiological mechanism</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Александров</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleksandrov</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чухловин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chukhlovin</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павловская</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlovskaya</surname><given-names>M. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костенко</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostenko</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Архипова</surname><given-names>Н. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Arkhipova</surname><given-names>N. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский научно-исследовательский нейрохирургический институт им. профессора А.Л. Поленова (филиал ФГБУ СЗФМИЦ им. В.А. Алмазова)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scienific Research Institute of Neurosurgery</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>07</day><month>05</month><year>2017</year></pub-date><volume>1</volume><issue>14</issue><issue-title>Современная функциональная диагностика</issue-title><fpage>46</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Александров М.В., Чухловин А.А., Павловская М.Е., Костенко И.А., Архипова Н.Б., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Александров М.В., Чухловин А.А., Павловская М.Е., Костенко И.А., Архипова Н.Б.</copyright-holder><copyright-holder xml:lang="en">Aleksandrov M.V., Chukhlovin A.A., Pavlovskaya M.E., Kostenko I.A., Arkhipova N.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/140">https://www.med-alphabet.com/jour/article/view/140</self-uri><abstract><p>Таламо-кортикальное взаимодействие в современной нейрофизиологии рассматривается как ключевой механизм генерации суммарной биоэлектрической активности. Согласно «таламической» теории генерации альфа-ритма частота залповой активности нейронов таламуса зависит от уровня поляризации их мембран. Накопленные к настоящему времени данные позволяют считать, что в основе генерации как альфа-ритма, так и тета-диапазона частот на ЭЭГ лежат единые механизмы. При гиперполяризации мембран таламических пейсмейкеров они меняют частоту разрядной активности с 10-12 Гц на 4-7 Гц. В результате на суммарной ЭЭГ регистрируется замедление доминирующей активности. Диапазон частот от 4 до 13 Гц может рассматриваться как «альфа-тета континуум)).</p></abstract><trans-abstract xml:lang="en"><p>Thalamo-cortical interactions within the framework of contemporary neurophysiology are to be regarded as the key mechanism of integral bioelectrical activity generation. According to the “thalamic” theory of alpha-rhythm generation, the frequency of burst-activity in thalamic neurons depends on their level of membrane polarization. The findings accumulated to date allow us to attribute the generation of alpha-rhythm and the theta-range oscillations on EEG to the same mechanisms. While hyperpolarized thalamic pacemaker neurons alter the frequency of their discharge activity from 10-12 Hz to 4-7 Hz. Consequently the overall EEG-activity demonstrates the decrease in frequency of predominant activity. The range of oscillation frequency between 4 and 13 Hz might be considered an “alpha-theta continuum”.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>биоэлектрическая активность головного мозга</kwd><kwd>электроэнцефалография</kwd><kwd>альфа-ритм</kwd><kwd>таламус</kwd></kwd-group><kwd-group xml:lang="en"><kwd>brain electrical activity</kwd><kwd>electroencephalography</kwd><kwd>EEG</kwd><kwd>alpha-rhythm</kwd><kwd>thalamus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Александров М. В., Иванов А. О., Бондаренко И. Ю. Состояние электрической активности мозга при острых отравлениях нейротоксикантами // Военно-медицинский журнал. - 2002. - № 3. - С. 4-9.</mixed-citation><mixed-citation xml:lang="en">Александров М. В., Иванов А. О., Бондаренко И. Ю. Состояние электрической активности мозга при острых отравлениях нейротоксикантами // Военно-медицинский журнал. - 2002. - № 3. - С. 4-9.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Александров М. В., Александрова Т.В Системность и специфичность действия психотропным средств на биоэлектрическую активность головного мозга при острых отравлениях // Вестник клинической нейрофизиологии. - 2016. - № 1. - С. 27-39.</mixed-citation><mixed-citation xml:lang="en">Александров М. В., Александрова Т.В Системность и специфичность действия психотропным средств на биоэлектрическую активность головного мозга при острых отравлениях // Вестник клинической нейрофизиологии. - 2016. - № 1. - С. 27-39.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Adrian E. D., Matthews B. H. The Berger rhythm: potential changes from the occipital lobes in man // Brain. - 1934. - Vol. 57. - P. 355-385.</mixed-citation><mixed-citation xml:lang="en">Adrian E. D., Matthews B. H. The Berger rhythm: potential changes from the occipital lobes in man // Brain. - 1934. - Vol. 57. - P. 355-385.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Andersen P., Andersson S. A. Physiological basis of the alpha rhythm. New York: Century Crofts, 1968-428 р.</mixed-citation><mixed-citation xml:lang="en">Andersen P., Andersson S. A. Physiological basis of the alpha rhythm. New York: Century Crofts, 1968-428 р.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Gastaut H. Some aspects of neurophysiological basis of conditioned reflexes and behaviour // Neurological basis of behaviour / Ed. By Wolstenholme GEW, O’Connor C. M. - London: Churchill, 1958. - P. 255-276.</mixed-citation><mixed-citation xml:lang="en">Gastaut H. Some aspects of neurophysiological basis of conditioned reflexes and behaviour // Neurological basis of behaviour / Ed. By Wolstenholme GEW, O’Connor C. M. - London: Churchill, 1958. - P. 255-276.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hughes S. W. and Crunelli V. Thalamic Mechanisms of EEG Alpha Rhythms and Their Pathological Implications // Neuroscientist. - 2005. - Vol. 11, N 4. - P. 357-372.</mixed-citation><mixed-citation xml:lang="en">Hughes S. W. and Crunelli V. Thalamic Mechanisms of EEG Alpha Rhythms and Their Pathological Implications // Neuroscientist. - 2005. - Vol. 11, N 4. - P. 357-372.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Niedermeyer E. Alpha rhythms as physiological and abnormal phenomena // Int. J. Psychophysiol. - 1997. - Vol. 26, N 1-3. - P. 31-49.</mixed-citation><mixed-citation xml:lang="en">Niedermeyer E. Alpha rhythms as physiological and abnormal phenomena // Int. J. Psychophysiol. - 1997. - Vol. 26, N 1-3. - P. 31-49.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Llinas R. R., Ribary U., Jeanmonod D., Kronberg E., Mitra P. P. Thalamocortical dysrhythmia: a neurological and neuropsychiatric syndrome characterized by magnetoencephalography // Proc / Natl. Acad. Sci. USA. - 1999 - Vol. 96 (26). - P. 15222-15227.</mixed-citation><mixed-citation xml:lang="en">Llinas R. R., Ribary U., Jeanmonod D., Kronberg E., Mitra P. P. Thalamocortical dysrhythmia: a neurological and neuropsychiatric syndrome characterized by magnetoencephalography // Proc / Natl. Acad. Sci. USA. - 1999 - Vol. 96 (26). - P. 15222-15227.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Longo V. G. Behavioural and electroencephalographic effects of atropin and related compounds // Pharmacol. Rev. - 1966. - Vol. 18, N 2. - P. 965-996.</mixed-citation><mixed-citation xml:lang="en">Longo V. G. Behavioural and electroencephalographic effects of atropin and related compounds // Pharmacol. Rev. - 1966. - Vol. 18, N 2. - P. 965-996.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Lopes da Silva F. H., van Lierop T. H., Schrijer C. F., van Leeuwen W. S. Organization of thalamic and cortical alpha rhythms: spectra and coherences // Electroencephalogr. Clin. Neurophysiol. - 1973. - Vol. 35, N 6. - P. 627-639.</mixed-citation><mixed-citation xml:lang="en">Lopes da Silva F. H., van Lierop T. H., Schrijer C. F., van Leeuwen W. S. Organization of thalamic and cortical alpha rhythms: spectra and coherences // Electroencephalogr. Clin. Neurophysiol. - 1973. - Vol. 35, N 6. - P. 627-639.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
