medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2019-3-32(407)-41-43medalphabet-1384Research ArticleСтатьиБезопасен ли 2‑феноксиэтанол при использовании в медицине и парфюмерно‑косметической продукции?Is 2-phenoxyethanol safe when used in medicine and cosmetics?МельниковаО. А.MelnikovaO. A.

д. фарм. н., проф., кафедра управления и экономики фармации

г. Екатеринбург

Ekaterinburg

ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава РоссииРоссияUral State Medical UniversityRussian Federation201923012020332Обозрение4143Copyright © Мельникова О.А., 20202020Мельникова О.А.Melnikova O.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/1384

В статье рассматриваются вопросы, связанные с использованием консерванта 2-феноксиэтанола в медицине и косметологии. Описывается область применения данного вещества в различных видах медицинских, фармацевтических и косметических товаров, его нахождение в природе в таких растениях, как авокадо, зеленый чай. Рассматриваются физические свойства 2-феноксиэтанола, механизм его действия. Обосновывается его содержание в товарах в дезинфицирующих средствах и кожных антисептиках (2 %) и парфюмерно-косметической продукции (1 %). Разбираются возможные проблемы безопасности при использовании данного вещества. Показано отсутствие раздражающего действия на кожу, отсутствие аллергических реакций на слизистую оболочку глаз, отсутствие случаев контактной аллергии и фотосенсибилизации, отсутствие токсичности и гемолитического эффекта.

This article discusses issues related to the use of the preservative 2-phenoxyethanol in medicine and cosmetology. The scope of this substance in various types of medical, pharmaceutical and cosmetic products, its presence in nature, in plants such as avocados, green tea, is described. The physical properties of 2-phenoxyethanol and its mechanism of action are considered. It substantiates its content in goods in disinfectants and skin antiseptics (2 %) and perfumes and cosmetics (1 %). Potential safety issues with this substance are discussed. The absence of irritating effects on the skin, the absence of allergic reactions to the mucous membrane of the eyes, the absence of contact allergies and photosensitization, the absence of toxicity and hemolytic effect have been shown.

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The authors declare that there are no conflicts of interest present.