medalphabetМедицинский алфавитMedical alphabet2078-56312949-2807ООО «Альфмед»10.33667/2078-5631-2019-2-17(392)-43-48medalphabet-1281Research ArticleСтатьиХимиолучевая терапия немелкоклеточного рака легкого: наиболее частые осложнения лечения и методы борьбы с нимиChemotherapy of Non-Small Cell Lung Cancer: Most Frequent Complications of Treatment and Methods of Dealing with themДеньгинаН. В.DenginaN. V.

к. м. н.

МитинТ. В.MitinT. V.

к. м. н., отделение радиационной медицины 

Department of Radiation Medicine

ЧерныхМ. В.ChernykhM. V.

к. м. н.

ГУЗ «Областной клинический онкологический диспансер», г. УльяновскРоссияRegional Clinical Cancer Centre, UlyanovskRussian FederationОрегонский университет здоровья и науки, г. ПортлендСоединённые Штаты АмерикиOregon Health & Science University, PortlandUnited StatesОнкорадиологический центр на базе ГБУЗ МО «Подольская городская клиническая больница», г. ПодольскРоссияOncoradiological Centre of Podolsk City Clinical Hospital, PodolskRussian Federation201927112019217Диагностика и онкотерапия4348Copyright © Деньгина Н.В., Митин Т.В., Черных М.В., 20192019Деньгина Н.В., Митин Т.В., Черных М.В.Dengina N.V., Mitin T.V., Chernykh M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-alphabet.com/jour/article/view/1281

Химиолучевая терапия является краеугольным камнем в лечении больных местнораспространенным немелкоклеточным раком легкого (НМРЛ). Тем не менее, по данным официальной статистики, в России подобное лечение проводится крайне редко, несмотря на то, что первичный местнораспространенный рак легкого выявляется у трети больных. Одной из наиболее частых причин, препятствующих более широкому применению метода, считается высокая токсичность химиолучевого лечения больных с опухолями внутригрудных локализаций. В данном обзоре приведены наиболее частые варианты осложнений и методы их профилактики и борьбы с ними.

Chemoradiotherapy is the cornerstone in the treatment of patients with locally advanced lung cancer. However, according to official statistics in Russia, such treatment is extremely rare, despite the fact that the primary locally advanced lung cancer is detected in more than 30 % of cases. One of the most frequent obstacles for the wider use of chemoradiotherapy is its high toxicity for patients with intrathoracic tumors. This review presents the most common complications and methods for their prevention, treatment and control.

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The authors declare that there are no conflicts of interest present.