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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.33667/2078-5631-2019-1-9(384)-38-46</article-id><article-id custom-type="elpub" pub-id-type="custom">medalphabet-1078</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Оценка клинической эффективности препарата Деринат® в форме спрея в практике участкового терапевта</article-title><trans-title-group xml:lang="en"><trans-title>Evaluation of clinical efficacy of Derinat® in form of spray in practice of district therapist</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабкин</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Babkin</surname><given-names>A. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зуйкова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zuikova</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Красноруцкая</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasnorutskaya</surname><given-names>O. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котова</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotova</surname><given-names>Yu. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бугримов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Bugrimov</surname><given-names>D. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Катаева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kashaeva</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сизова</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Sizova</surname><given-names>N. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Воронежский государственный медицинский университет имени Бурденко» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sizova Voronezh State Medical University n. a. Burdenko</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный медико-стоматологический университет имени А. И. Евдокимова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medicine and Dentistry n. a. A. I. Evdokimov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В. И. Кулакова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Obstetrics, Gynecology and Perinatology n. a. academician V. I. Kulakov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>23</day><month>03</month><year>2019</year></pub-date><volume>1</volume><issue>9</issue><issue-title>Современная поликлиника</issue-title><fpage>38</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бабкин А.П., Зуйкова А.А., Красноруцкая О.Н., Котова Ю.А., Бугримов Д.Ю., Катаева О.В., Сизова Н.М., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Бабкин А.П., Зуйкова А.А., Красноруцкая О.Н., Котова Ю.А., Бугримов Д.Ю., Катаева О.В., Сизова Н.М.</copyright-holder><copyright-holder xml:lang="en">Babkin A.P., Zuikova A.A., Krasnorutskaya O.N., Kotova Y.A., Bugrimov D.Y., Kashaeva O.V., Sizova N.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/1078">https://www.med-alphabet.com/jour/article/view/1078</self-uri><abstract><p>Широкое распространение во всем мире острых респираторных заболеваний является актуальной проблемой в здравоохранении. Выраженная полиэтиологичность респираторных заболеваний не позволяет ограничиться применением только специфических вакцинных препаратов и диктует необходимость использования для борьбы с ними различных неспецифических средств, стимулирующих естественную резистентность организма человека. Главным фармакологическим действием натрия дезоксирибонуклеата является стимуляция фагоцитирующей активности Т-хелперов и 7-киллеров, повышения функциональной активности нейтрофилов и моноцитов/макрофагов, обеспечивающих процессы регенерации и репарации в эпителиальном компоненте противовирусной защиты организма. На основании вышеизложенного изучение клинической эффективности препарата Деринат® в форме спрея в терапии ОРВИ представляется актуальным.</p></abstract><trans-abstract xml:lang="en"><p>The widespread worldwide spread of acute respiratory diseases is an urgent problem in health care. Expressed polyetiology of respiratory diseases does not allow to limit the use of specific vaccine preparations and dictates the need to use to combat them a variety of non-specific means that stimulate the natural resistance of the human body. The main pharmacological action of sodium deoxyribonucleate is the stimulation of phagocytic activity of T-helpers and T-killers, increasing the functional activity of neutrophils and monocytes/ macrophages, providing regeneration and repair processes in the epithelial component of antiviral protection of the body. Based on the above, the study of the clinical efficacy of Derinat® in the form of spray in the treatment of acute respiratory viral infections is relevant.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ОРВИ</kwd><kwd>деринат</kwd><kwd>спрей</kwd><kwd>натрия дезоксирибонуклеат</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute respiratory viral infections</kwd><kwd>Derinat®</kwd><kwd>spray</kwd><kwd>sodium desoxyribonucleate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
