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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medalphabet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский алфавит</journal-title><trans-title-group xml:lang="en"><trans-title>Medical alphabet</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2078-5631</issn><issn pub-type="epub">2949-2807</issn><publisher><publisher-name>ООО «Альфмед»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medalphabet-1043</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group></article-categories><title-group><article-title>Раннее назначение генно-инженерной биологической терапии пациентам с псориазом</article-title><trans-title-group xml:lang="en"><trans-title>Early appointment of biological therapy of psoriasis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Круглова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kruglova</surname><given-names>L. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хотко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Hotko</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрий</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Petriy</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ ДПО «Центральная государственная медицинская академия» Управления делами Президента Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central State Medical Academy of the Administrative Department of the President of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ «Клинический кожно-венерологический диспансер» Минздрава Краснодарского края</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Dermatovenerologic Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>05</day><month>03</month><year>2019</year></pub-date><volume>1</volume><issue>7</issue><issue-title>Дерматология</issue-title><fpage>25</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Круглова Л.С., Хотко А.А., Петрий М.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Круглова Л.С., Хотко А.А., Петрий М.А.</copyright-holder><copyright-holder xml:lang="en">Kruglova L.S., Hotko A.A., Petriy M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-alphabet.com/jour/article/view/1043">https://www.med-alphabet.com/jour/article/view/1043</self-uri><abstract><p>Статья носит обзорный характер и содержит актуальную информацию о применении генно-инженерных препаратов у пациентов с псориазом, псориатическим артритом в проекции концепции раннего назначения биологической терапии. Приводятся данные о целесообразности раннего назначения генно-инженерных препаратов для улучшения прогноза течения заболевания и повышения качества жизни.</p></abstract><trans-abstract xml:lang="en"><p>The article is of a review nature and contains up-to-date information on the use of genetically engineered drugs in patients with psoriasis, psoriatic arthritis in the projection of the concept of early prescription of biological therapy. The data on the feasibility of early use of genetically engineered drugs to improve the prognosis of the disease and improve the quality of life.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>псориаз</kwd><kwd>псориатический артрит</kwd><kwd>коморбидность</kwd><kwd>генно-инженерные препараты</kwd><kwd>устекинумаб</kwd><kwd>раннее назначение генно-инженерных препаратов</kwd></kwd-group><kwd-group xml:lang="en"><kwd>psoriasis</kwd><kwd>psoriatic arthritis</kwd><kwd>comorbidity</kwd><kwd>genetically engineered drugs</kwd><kwd>ustekinumab</kwd><kwd>early prescription of genetically engineered drugs</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
